Total 46 Others level Science / R&D / Research job vacancies in CB2 3HH

Your new company
You will be joining a world leading research institute based in the Cambridge area - who have a wide range of partnerships within academia and pharmaceutical & biotech companies - focusing on research within cancer.
The institution has invested heavily in equipment and lab upgrades and fosters a highly collaborative and friendly work environment, where you will be working with leading experts within cancer and biological research.They also offer very generous benefits, a flexible approach to working and make significant investment into the training and development of their staff, so there will be a number of opportunities to develop new and advance existing skills.


Your new role
You will be joining a prestigious research group working with some of the leading scientists in the genetics field carrying out research work to identify new approaches to tackle cancer.
Main responsibilities will include:

• Lead innovative research in molecular biology to uncover fundamental mechanisms related to genetic and protein functions in cancer.
• Investigate interactions between modified bases and proteins, focusing on their impact on genome functions like transcription and chromatin organisation.
• Develop new techniques to study the dynamics of modified bases and their binding proteins, utilising chemical and genetic approaches.
• Analyse genetic/genomic and other omics data sets to provide insights and use these to design future experiments.
• Explore genetic targets for synthetic lethality opportunities in cancer.
• Manage your own research projects while collaborating with others, ensuring meticulous record-keeping and resource management.
• Share your findings through presentations and publications, and help to mentor PhD students.

What you'll need to succeed
As well as strong communication and organisational skills, you should have:

• A PhD (or be nearing completion) in molecular biology, biochemistry, cancer genomics, or related fields, or significant equivalent experience
• Proficiency in molecular biology techniques, including RNA/DNA analysis, PCR, protein analysis, and western blotting.
• Advanced cloning skills, with experience in genetic engineering, vector construction, and CRISPR/Cas9 systems.
• Expertise in recombinant protein design and expression, utilising systems like E. coli, along with purification methods such as FPLC and mass spectrometry.
• Familiarity with genomic technologies like ChIP-seq, RNA-seq, and single-cell methods, preferably within oncology research, though this is not essential.

It would be an advantage to have good data analysis skills and experience using programming / scripting languages such as Python and/or R, along with tools like MATLAB and Bioconductor, however training can be provided.

What you'll get in return
An exciting opportunity to work with one of the leading research institutes in the country, excellent career and skills development, a great working atmosphere and the chance to make a real impact on cancer research.


What you need to do now
If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call me on 0203 465 0057.
If this job isn't quite right for you but you are looking for a new position, please contact us for a confidential discussion on your career.

Keywords: biology, biologist, molecular, cell, gene, expression, editing, CRISPR, Cas9, recombinant, protein, NGS, genetic, genomic, cancer, cloning, vector, RNAseq, ChIPseq, research, science, pharmaceutical, biotech, drug, discovery, development, R&D, R, python

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. Please note:- Internal applicants on permanent contracts can only apply for this post as a secondment and must have the approval of your current line manager before applying. As per Home Office guidelines, please be aware that, unfortunately, the Trust is unable to offer sponsorship for this particular position. This vacancy will close at midnight on 15th September 2024 Interviews are due to be held on 26th September 2024 Benefits to you At Cambridge University Hospitals, we want to do all we can to support good working days. We offer development opportunities and a wide range of benefits, including on-site leisure facilities, shopping concourse and day nurseries. Our good work programme currently includes providing reduced cost Stagecoach bus travel to and from Cambridge University Hospital site. Park and Ride bus journeys between Babraham Road and Trumpington sites are free, as is the route to and from Cambridge train station and our hospitals. We also subsidise the cost of parking on site for eligible staff. On CUH campus, hot food is available 24/7 and at a reduced cost for colleagues. Recently we launched the first of our staff pod break spaces. Located in the Deakin Centre, we have a purpose-created colleague-only caf, with free tea and coffee, a break space and private outside area for colleagues to rest, refuel and recharge. Just one of the ways we are working hard to support good working days at CUH. CUH is committed to assisting employees in achieving a good work-life balance irrespective of role or personal circumstances. Flexible arrangements may include, but are not limited to, part-time working, job-share, term-time working and flexible start and finish times. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. Due to Home Office immigration rules, a full time permanent vacancy cannot be filled by individuals on a Student visa. Therefore, please be advised that if you are a Student visa holder, we will not be able to offer you a full time permanent contract unless you have:- applied for a Graduate visa- or you will have successfully completed your course and have applied for a Graduate visa before the anticipated start date of your employment- or the Trust has agreed that they will Sponsor you as a Skilled Worker and you will complete your studies within 3 months of the anticipated start date of employment. This vacancy will close at midnight on 6th November 2024 Interviews are due to be held week commencing 18th November 2024 Benefits to you At Cambridge University Hospitals, we want to do all we can to support good working days. We offer development opportunities and a wide range of benefits, including on-site leisure facilities, shopping concourse and day nurseries. Our good work programme currently includes providing reduced cost Stagecoach bus travel to and from Cambridge University Hospital site. Park and Ride bus journeys between Babraham Road and Trumpington sites are free, as is the route to and from Cambridge train station and our hospitals. We also subsidise the cost of parking on site for eligible staff. On CUH campus, hot food is available 24/7 and at a reduced cost for colleagues. Recently we launched the first of our staff pod break spaces. Located in the Deakin Centre, we have a purpose-created colleague-only caf, with free tea and coffee, a break space and private outside area for colleagues to rest, refuel and recharge. Just one of the ways we are working hard to support good working days at CUH. CUH is committed to assisting employees in achieving a good work-life balance irrespective of role or personal circumstances. Flexible arrangements may include, but are not limited to, part-time working, job-share, term-time working and flexible start and finish times. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces.

Detailed job description and main responsibilities This post will be based within the Acute Conditions Research Team, supporting research studies within various disciplines including but not exclusively, Anaesthetics, ICU, Surgery, ED/Trauma, MSK and Stroke.You will be working as part of our small, friendly team, responsible for identifying, recruiting and supporting patients throughout their research journey. The post is primarily based at Blackburn Royal Teaching Hospital. However, the post holder may also be expected to support trials at Burnley General Teaching Hospital and other Trust sites, to meet the needs of our patients and studies. Therefore flexibility is an essential attribute. Most of the research activity is undertaken Monday to Friday within normal office hours. However, research activity times may also vary and early starts (7:30 onwards) or late finishes (after 5pm) may be required to accommodate studies involving morning theatre lists & late running clinics. This will always be on a planned basis & a flexible working policy is in place.Our team ethos is to maximize the potential of our own, individual skills. We support each other to be the best we can be. Every member of our team is of equal importance and we welcome new ideas. Our focus is always on providing the best possible care for research participants in East Lancashire.

Please refer to the attached job description and person specification for full details of responsibilities To interpret and analyse data from a variety of sources (including psychological articles, intervention manuals/protocols, training materials, and case studies) and integrate these with theoretical and therapeutic models and complex factors concerning historical and developmental processes that shape individuals, families, and communities. To develop psychological frameworks of parenting skills and features of parent-child interactions that integrate information from available literature within a coherent framework that draws upon psychological theory and evidence, and that incorporates interpersonal, societal, cultural and biological factors. To co-lead focus groups and consultations with practitioners across NHS and third sector services (e.g., health visitors, clinical psychologists, psychotherapists, occupational therapists, social workers) to gain insights through sharing experiences of evidence-based practice and integrating learning. To co-lead focus groups and consultations with caregivers of young children in public and patient involvement initiatives that aim to co-produce guidance for cross-service use. To exercise autonomous professional responsibility for project outputs (e.g., service frameworks, literature reviews, reports, and guidance) in line with service guidelines and under the overall co-ordination of the Principal Investigators. To communicate, in a skilled and sensitive manner, to other practitioners, service users, and other key stakeholders as appropriate. To attend and contribute to team meetings and discussions. To work in partnership with other disciplines and to maintain links with Statutory and non-statutory and primary care agencies as appropriate. To contribute to the reduction of risk in areas of responsibility. To produce project reports and notes in a timely manner and to provide management information in line with Trust policies and procedures in a timely manner.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. Please note:- Internal applicants on permanent contracts can only apply for this post as a secondment and must have the approval of your current line manager before applying. This vacancy will close at midnight on 1st September 2024 Interviews are due to be held on 20th September 2024 Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces. For further details / informal visits contact: Marie Baker Business Support Officer - East GMSA egmsa@nnuh.nhs.uk

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on 1st September 2024 Interviews will be held at the end of September/beginning of October. Due to recent changes in Immigration and Sponsorship rules, only those with at least two years relevant NHS experience in this role will currently meet the required salary threshold for Sponsorship. If you will require Sponsorship and you currently have a Visa under which you can work, but it is due to expire before you have been able to gain two years relevant NHS experience to meet the required salary threshold, the Trust will not be able to Sponsor you.Due to Home Office immigration rules, a full time permanent vacancy cannot be filled by individuals on a Student visa. Therefore, please be advised that if you are a Student visa holder, we will not be able to offer you a full time permanent contract unless you have:- applied for a Graduate visa- or you will have successfully completed your course and have applied for a Graduate visa before the anticipated start date of your employment- or the Trust has agreed that they will Sponsor you as a Skilled Worker and you will complete your studies within 3 months of the anticipated start date of employment Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered. We welcome applications from the Armed Forces.

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


Applications are invited for the post of Clinical Research Fellow (Core) in Otolaryngology (ENT) and Digital Health Technologies at Addenbrooke's Hospital, part of Cambridge University Hospitals NHS Foundation Trust.

This post is available asap until 5 August 2025.

This post is primarily clinically based and will allow the candidate to achieve proficiency in many core aspects of Ear, Nose and Throat surgery. Candidates should have >2 years experience of practicing medicine. This post will enable the individual build their portfolio towards a competitive advantage with Core Surgical, ST3 applications or alternative routes to progression to higher surgical training / experience.



Substantial time is allocated for the development of clinical research in digital health technologies. This includes the application of technologies such as mixed reality, extended reality, Artificial Intelligence, etc in education, training and clinical care. The candidate will have a dedicated educational supervisor for the placement with specific goals and a career development plan. The research aspects of the job benefits from the support of the CUH digital health and simulation centre.



Please note that these posts do not carry Postgraduate Dean’s approval or training recognition.

This post may be suitable for those wishing to undertake an “F3” role.

Full Registration and a Licence to Practice with the General Medical Council at time of application is required.

The applicant must have demonstrable skills in listening, reading, writing and speaking in English that enable effective communication about medical topics with patients and colleagues, as set out in the GMC’s Good Medical Practice (2013). Non-UK applicants must possess the IELTS/OET exam before obtaining a GMC licence to practice.

Applications from job seekers who require skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website.

It is a requirement for skilled worker applicants, applying for entry clearance into the UK, to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) will also be subject to this requirement.

Cambridge University Hospitals NHS Foundation Trust is an Equal Opportunities Employer.

The post holder will be expected to take part in a full-shift rolling rota that provides a balanced combination of consultant supervised, firm based teaching with clinical work covering the ward, referrals from A&E and ENT emergency clinics. You will rotate through sub-specialty firms in Head and Neck, Rhinology, Paediatric ENT and Otology, Cochlear Implantation and Skull Base surgery. You are also required to attend the department’s medical audit, morbidity and mortality meetings and the in-house continuing medical education programme. The individual will be expected to complete a robust research project in digital health including publication in a peer review journal. This will be among other research goals. There will be opportunities to deliver teaching as part of a faculty on digital technology.



Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.


This advert closes on Wednesday 21 Aug 2024

The post holder will be expected to take part in a full-shift rolling rota that provides a balanced combination of consultant supervised, firm based teaching with clinical work covering the ward, referrals from A&E and ENT emergency clinics. You will rotate through sub-specialty firms in Head and Neck, Rhinology, Paediatric ENT and Otology, Cochlear Implantation and Skull Base surgery. You are also required to attend the departments medical audit, morbidity and mortality meetings and the in-house continuing medical education programme. The individual will be expected to complete a robust research project in digital health including publication in a peer review journal. This will be among other research goals.There will be opportunities to deliver teaching as part of a faculty on digital technology. Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. If you require sponsorship for a Visa to work in the UK, to avoid disappointment, please check you are not applying from a Red list country - Code of practice for the international recruitment of health and social care personnel in England - GOV.UK (www.gov.uk) Closing date is midnight on 26 August 2024 Interviews are due to be held on 12 September 2024 Why choose Cambridge University Hospitals? Our values and reputation for outstanding care Opportunities to experience a range of specialities Career and development opportunities Preceptorship and mentoring programmes delivered by a dedicated clinical education support team Research experience and opportunities Lovely location and quality of life Excellent schools/colleges and transport links (road, rail and air) Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered. We welcome applications from the Armed Forces.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. Please note:- Internal applicants on permanent contracts can only apply for this post as a secondment and must have the approval of your current line manager before applying. If you require sponsorship for a Visa to work in the UK, to avoid disappointment, please check you are not applying from a Red list country - Code of practice for the international recruitment of health and social care personnel in England - GOV.UK (www.gov.uk) Closing date is midnight on 14 August 2024 Interviews are due to be held on 22 August 2024 Why choose Cambridge University Hospitals? Our values and reputation for outstanding care Opportunities to experience a range of specialities Career and development opportunities Preceptorship and mentoring programmes delivered by a dedicated clinical education support team Research experience and opportunities Lovely location and quality of life Excellent schools/colleges and transport links (road, rail and air) Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered. We welcome applications from the Armed Forces.

You will have an opportunity to work with world leading collaborators and to develop skills in cutting-edge clinical trials, trials conduct and delivery, data analysis and statistics, writing research protocols and HRA applications, manuscript writing and presentations, for example. You will gain training in Good Clinical Practice and provide clinical support for trials, conduct trial assessments and gain skills in pharmacovigilance and study reporting. This is an excellent opportunity for individuals with an interest in research and they would be supported to develop their own research interests and encouraged to register for a higher degree. The post holder will also be required to fulfil clinical commitments within Cambridge University Hospitals NHS Foundation Trust and it is expected this would be one sessions a week by arrangement. Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


Applications are invited for the post of Clinical Research Fellow Core (ST1-2) / Higher (ST3-5/ST6+) in Respiratory Clinical Trials based in Clinical Pharmacology.

We are seeking to appoint a Clinical Research Fellow who will be embedded in a multi-disciplinary clinical research unit with strong links with the University of Cambridge, working in clinical trials, primarily in Respiratory Medicine.

The Clinical Research Fellow will be supervised by Dr Marie Fisk, COPD Researcher and Professor Ian Wilkinson, Head of the Cambridge Clinical Trials Unit at Cambridge University Hospitals NHS Foundation Trust.

This is a full-time post is available from July/August 2024 for up to three years and will involve working within the departments of Clinical Pharmacology and Respiratory Medicine, but a minimum term of 12 months may be considered by arrangement.

In order to be considered applicants must have:
• Degree in Medicine (MBBS or equivalent).
• MRCP or equivalent qualification.
• Full Registration and a Licence to Practice with the General Medical Council at point of application.

Applicants who have completed Foundation training and are either planning to apply for, or already have Core Medical or Specialist training experience (or equivalent) with interest in Respiratory Medicine, General Medicine, or Clinical Pharmacology or Cardiovascular Medicine and research would be well suited to this post.

Please note that this post does notcarry Postgraduate Dean’s approval or training recognition.

This post may be suitable for those wishing to undertake an “F3” role.

The applicant must have demonstrable skills in listening, reading, writing and speaking in English that enable effective communication about medical topics with patients and colleagues, as set out in the GMC’s Good Medical Practice (2013). Non-UK applicants must possess the IELTS/OET exam before obtaining a GMC licence to practice.

Applications from job seekers who require skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website.

It is a requirement for skilled worker applicants, applying for entry clearance into the UK, to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) will also be subject to this requirement.

Cambridge University Hospitals NHS Foundation Trust is an Equal Opportunities Employer.

You will have an opportunity to work with world leading collaborators and to develop skills in cutting-edge clinical trials, trials conduct and delivery, data analysis and statistics, writing research protocols and HRA applications, manuscript writing and presentations, for example.

You will gain training in Good Clinical Practice and provide clinical support for trials, conduct trial assessments and gain skills in pharmacovigilance and study reporting. This is an excellent opportunity for individuals with an interest in research and they would be supported to develop their own research interests and encouraged to register for a higher degree.

The post holder will also be required to fulfil clinical commitments within Cambridge University Hospitals NHS Foundation Trust and it is expected this would be one sessions a week by arrangement.

Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.


This advert closes on Wednesday 24 Jul 2024

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


Applications are invited for a Clinical Research Fellow Higher (ST3-5) in Cancer Trials with Cambridge University Hospitals NHS Foundation Trust available from 18 July 2024 for 12 months.

This is an exciting opportunity for a Physician wanting to develop their career and gain experience as a Clinical Researcher within the Cancer Directorate at CUH.

This post may be suitable for Trainees, either before or after specialist Oncology training (or equivalent) and appropriate training, according to the level of the appointee’s experience, will be offered, and monitored by a named Senior Supervisor. A knowledge of clinical trial delivery and Good Clinical Practice (GCP), relating to trials would be an advantage.

The successful applicant will work in close collaboration with Senior Investigators and research staff in the day-to-day care and management of patients on trials, receiving experimental treatment both in early and late phase settings.

This post will offer the opportunity for training in all aspects of trial delivery from conception through to completion. The appointee will attend research-orientated outpatient clinics, participating in multidisciplinary teams for the management of solid and haematological cancers. Direct participation in research and audit projects is strongly encouraged.

The successful candidate will have some experience in Oncology, combined with a desire to enhance their knowledge and skills in relation to the conduct of clinical trials in patients with cancer.

In order to be considered applicants must meet the essential criteria outlined in the person specification.

Please note that this post does not carry Postgraduate Dean’s approval or training recognition.

Full Registration and a Licence to Practice with the General Medical Council at time of application.

The applicant must have demonstrable skills in listening, reading, writing and speaking in English that enable effective communication about medical topics with patients and colleagues, as set out in the GMC’s Good Medical Practice (2013). Non-UK applicants must possess the IELTS/OET exam before obtaining a GMC licence to practice.

Applications from job seekers who require skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website.

It is a requirement for skilled worker applicants, applying for entry clearance into the UK, to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) will also be subject to this requirement.

Cambridge University Hospitals NHS Foundation Trust is an Equal Opportunities Employer.

Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.


This advert closes on Monday 1 Jul 2024

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. Closing date is midnight on 4 July 2024 Interviews are due to be held on 19 July 2024 Why choose Cambridge University Hospitals? Our values and reputation for outstanding care Opportunities to experience a range of specialities Career and development opportunities Preceptorship and mentoring programmes delivered by a dedicated clinical education support team Research experience and opportunities Lovely location and quality of life Excellent schools/colleges and transport links (road, rail and air) Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered. We welcome applications from the Armed Forces.