Total 116 accounts manager job vacancies in Science / R&D / Research category in The United States of America

ob Summary:

This is an individual contributor role where the Assistant Actuarial Manager will report to the Director and be responsible for contributing Asset Liability Management (ALM) related expertise to financial risk management, financial reporting and analysis, and product development to maximize value for the company. The Assistant Manager will collaborate across the Singapore team, including working directly with the Chief Actuary and will also collaborate with colleagues in our Regional Office and across the globe. The role provides excellent exposure and career development opportunities for strong candidates. This is a unique opportunity to help the Singapore business grow its presence within the High Net Worth market space while managing its profitability and risk levels. We offer a competitive benefit package and actuarial exam support.

Key Responsibilities:

• Production of ALM related quarter end deliverables such as Explanation of Investment Results (EoIR) for Drivers of Earnings (DOE), Earnings at Risk (EaR), Capital at Risk (CaR) and other management reporting requirements
• Conduct robust analysis into company financials on ALM matters and collaborate with other ALM teams, Finance, Investment and Regional/Corporate Office to implement mitigation strategies such as hedging
• Provide technical support to the pricing team on ALM matters for new product initiatives as well as inforce management for existing products
• Lead drafting of investment Portfolio Policies and Parameter (PPP) for new products and reviewing PPP for existing products
• Collaborate with other employees to build and enhance processes to ensure efficient workflows and a strong control environment
• Conduct any ad-hoc risk quantification & analysis and contribute to mitigation strategies and alternatives.
• Additional duties as may be required from time to time by Senior Management.

Job Requirements

• Minimum of 5 years of experience in Life Insurance industry
• Actuarial exam progression with a recognized international actuarial body, investment track is preferred (Eg: SOA QFI and IFoA SP5, SP6 and SA7)
• Experience with any valuation/capital framework is preferred (Eg: IFRS17, Economic Capital, RBC2, Solvency II)
• Experience and proficiency in Microsoft Office is required
• Strong technical skills and problem-solving ability, able to work in a dynamic environment
• Strong cross team collaboration skills
• Experience with Moody’s AXIS or an alternative actuarial modelling software is preferred

We offer attractive salary, group life and group medical insurance; and excellent career development opportunities to the right candidate.

We are an equal opportunity employer and welcome applications from all qualified candidates. Application forms and resume will be kept for a period of 24 months after completion of the recruitment process. (All information will be held in strict confidence and only be used for recruitment purpose).

Income's Actuarial team has been at the forefront of digitisation, innovation, and embracing the future of work. As today's business problem becoming more complex and uncertain, we acknowledge the importance of being adaptable and open to learning in solving the right problem. We adopted agile and design-thinking principles in delivering our projects at work and play a key role in enabling the organization strategic goals.

This role will expose you to how Actuarial could take customer-centric perspectives and iterative prototyping approach to solve complex problem more effectively. You will also get to apply new technology and data analytics to automate actuarial work as well as providing impactful insights to our business partners.

We are looking for a team player within the financial reporting team with the following key responsibilities:

• Key player in Par fund management including bonus investigation and recommendation, asset share study, bonus implementation and the review of Par fund management framework
• Assist team lead in Par fund related initiatives and projects
• The role will provide first hand exposure to chief actuary as well as opportunities to enhance actuarial technical knowledge and play a key role in adopting new technologies
• Participate in ad-hoc projects and tasks based on department priorities
• Ensure deliveries follows the department's best practice on risk and compliance

Requirements

• Bachelor Degree in Actuarial Science or equivalent
• Good progress in actuarial qualifications with either US, UK, or Australia Actuarial Institute or newly qualified actuary, with at least 4 to 6 years of work experience in actuarial function, with exposure to financial reporting and have par fund management expereince
• Technical, meticulous and able to apply critical thinking
• Excellent communication skills, both oral and written
• Able to work independently and collaborate with other team members and departments
• Adaptable, open to a dynamic working environment and willing to explore new ways of working
• Experience in using Prophet and data software such as Alteryx will be a plus

Company Overview:

Paratus Sciences (www.paratussciences.com) is a biotech startup dedicated to improving human health through an understanding of bat biology. We focus on identifying and developing groundbreaking therapeutics for a myriad of diseases by unlocking the secrets of the bat genome. The company received $100 million Series A financing in 2021.

In addition to powered flight, bats have evolved the ability to control inflammation, tolerate viral infection, resist cancer, accept extreme diets, and live exceptionally long lives for a mammal of their size. However, the elusive lifestyle of bats coupled with a lack of scientific tools and reagents has made the study of these extraordinary animals difficult and slow going. We are developing the tools and methods necessary to understand the extreme and unique attributes of bat biology and apply these insights to identify and develop new therapies to address some of the most challenging health issues facing humankind.

Position Overview:

Paratus Sciences is looking for an R&D Project and Operations Manager to join us at our Singapore site. Reporting to the Site Head and VP of Discovery Research, the focus for this role will be project management support for the R&D team, and managing site operations. The ideal candidate will have a background in the Life Sciences and experience in the biotech and drug discovery sector. You will collaborate closely with the Site Head and R&D team to coordinate the successful execution of R&D projects, optimize processes, and oversee operational aspects of the site. We are seeking a committed and collaborative team member who will thrive in a dynamic culture.

Responsibilities:

Project Management (primary responsibility)

• Serve as a coordinator on cross-functional teams to drive the successful execution of R&D projects.
• Develop and maintain project plans, timelines and milestones to track progress and ensure alignment with company goals.
• Facilitate communication and collaboration among team members, stakeholders, and external partners to align project goals and priorities.
• Identify and mitigate project risks, resolve issues, and ensure timely delivery of project deliverables.
• Coordinate project planning, scheduling, and milestone tracking to ensure timely delivery of project objectives.
• Create and maintain accurate and up-to-date project documentation, including project plans, meeting minutes, and progress reports.

Operations Management (secondary responsibility)

• Oversee day-to-day operational activities to ensure efficient and effective functioning of the Singapore site.
• Manage site operations, including the coordination with facilities management, IT, and corporate services.
• Develop and implement operational processes, policies, and procedures to optimize workflow and productivity.

Budget and Resource Management

• Work closely with management to develop and manage project budgets, forecasts, and expenditures.
• Monitor resource allocation and utilization to maximize efficiency and cost-effectiveness.
• Identify opportunities for cost savings and resource optimization while maintaining high-quality standards.

Qualifications and Skills:

• Bachelor's, Master’s or PhD degree in the Life Sciences or a related field; advanced degree or certification in project management (e.g., PMP) is preferred.
• Minimum of 3 years of experience in project management within the biotech industry. Experience with operations management or related roles is a nice to have.
• Proven track record of successfully managing cross-functional teams and projects from conception to completion.
• Strong organizational, analytical, and problem-solving skills with the ability to prioritize tasks and meet deadlines in a fast-paced environment.
• Excellent communication, interpersonal, and leadership skills with the ability to build effective relationships and influence stakeholders at all levels.
• Proficiency in project management methodologies, software and other relevant tools.
• Experience in budget management and reporting would be considered a plus.
• Team player with a positive, proactive, can-do attitude.

Income's Actuarial team has been at the forefront of digitisation, innovation, and embracing the future of work. As today's business problem becoming more complex and uncertain, we acknowledge the importance of being adaptable and open to learning in solving the right problem. We adopted agile and design-thinking principles in delivering our projects at work and play a key role in enabling the organization strategic goals.

This role will expose you to how Actuarial could take customer-centric perspectives and iterative prototyping approach to solve complex problem more effectively. You will also get to apply new technology and data analytics to automate actuarial work as well as providing impactful insights to our business partners.

We are looking for a team player within the financial reporting team with the following key responsibilities. The role will provide first hand exposure to chief actuary and senior management as well as opportunities to enhance actuarial technical knowledge and play a key role in adopting new technologies.

Responsibilities

• Deliver management reporting on Embedded Value (EV) and New Business Embedded Value (NBEV) and highlight insights to management
• As the Prophet Manager, the role is responsible in ensuring Prophet model governance framework is in line with industry best practice and upholding the standards for Prophet development work
• Collaborate with Finance department to deliver business planning and forecasting key financial metrics (NBEV, Insurance Operating Results) and variance analysis
• Provide guidance and review the work of team members to ensure timely and high quality deliverables
• Participate in ad-hoc projects based on department priorities
• Ensure deliveries follows the department's best practice on risk and compliance

Requirements

• Bachelor degree in Actuarial Sciance or equivalent
• Good progress in actuarial qualifications with US, UK, or Australia Actuarial Institute or newly qualified actuary
• 6 to 9 years of work experience in actuarial functions, preferably in financial reporting and Prophet modelling
• Technical, meticulous, and able to apply critical thinking
• Able to communicate in simple and concise way to stakeholders
• Able to work independently and collaborate with other team members within actuarial and other departments
• Adaptable, open to a dynamic working environment and willing to explore new ways of working
• Experience in stochastic modelling will be a plus

Responsibilities:

• Perform reconciliation on equities/products to ensure accuracy with upstream custodians.
• To identify the breaks and resolve discrepancies.
• Responsible for MAS yearly valuation reporting and Statutory Board quarterly statistic reporting.
• Perform the extraction of agent’s data for Fatca/CRS reporting and check the data extracted to ensure accuracy.
• Responsible for Signature verification and world check on transfer matters.
• Perform as checker for reconciliation performed by team-mates.
• Be the Checker for SG trade affirmation, crypto transfers and Satoshi test
• Any other tasks which may be assigned from time to time.

Requirements:

• Minimum 3 - 6 years relevant experience
• Possess critical thinking and problem solving skills
• Ability to work under independently under pressure and collaborate with internal stakeholders
• Demonstrate excellent verbal and written communication skills

We apologize that only shortlisted candidates will be contacted. Thank you

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PERSOLKELLY Singapore Pte Ltd • RCB No. 200007268E

EA Registration No. R1653100 (Goh Jia Zhen Crystal)

FocusCore is working exclusively with a leading general insurer based in Singapore. The company is looking for a Actuarial Reserving Manager to join the valuation team.

In your role as a actuarial reserving manager, your responsibilities will encompass several key areas. These include assessing and calculating reserves, particularly following the guidelines of the IFRS17 standard, as well as participating in business planning and capital management efforts. Additionally, you will provide valuable assistance to the senior stakeholders by offering insights into risks, underlying performance, and their implications for the business. Furthermore, part of your role will involve mentoring junior members of the actuarial team.

Apply if you have over 6 years of experience within the general insurance space. Actuarial reserving experience is required. Email your CV to fairuz@focuscoregroup.com

EA License 16S8145

MOM Registration: R1104997

Assistant Manager / Manager, R&D

About CorDx:

CorDx is a multi-national biotech organization focused on pushing the limits of innovation and supply in global health. With over 2,000 employees across the world, serving millions of users in over 100 countries.

CorDx is transforming the global diagnostics industry with innovative R&D solutions, a vertically integrated supply chain, and manufacturing footprints in the United States and around the world.

With nearly two decades of IVD experience, CorDx is a leader in IVD research and development, manufacturing, and supply chain. Our proprietary line of rapid diagnostic products is recognized by families and medical professionals for reliability, affordability, and rapid results.

CorDx delivers rapid testing and point-of-care medical device solutions used in the detection of infectious disease such as COVID-19, pregnancy, drugs of abuse, biomarkers, and more. CorDx is at the cutting edge of technology, artificial intelligence, and data science with the goal of delivering diagnostic solutions to some of the most critical questions in healthcare.

Job Responsibilities

• Responsible for new product development, experiment and optimize buffer composition, reagents and recipes;
• Responsible for the testing and experiments of key raw materials, able to independently plan, analyze and summarize experimental data;
• Responsible for solving technical problems encountered during the research, development & production process;
• Strictly comply with laboratory-related operation and quality management requirements
• Collaborate with cross-functional teams to meet projects goals with overall organizational objectives.
• Any other ad-hoc duties or projects as required by the management team.

Qualifications:

• Experience in IVD, clean environment production, quality system, R&D and etc;
• Expertise in the operation and maintenance of lab instruments and data systems;
• Understand the relevant requirements of the production quality system for in vitro diagnostic products;
• A bachelor's degree with 7 years of relevant experience, a master's degree with 3 years of relevant experience, or a doctorate degree with at least 1 year of relevant experience. Others are welcome to apply.
• Familiar with in vitro diagnostic products such as lateral flow immunoassay, PCR, Immunoassay etc;
• Familiar with IVD product development and commercialization life cycle;
• Systematical project management, good planning, execution and timely communication. Good presentation skills.
• Majoring in biology, medicine, laboratory science, immunology, pharmacy or quality engineering are preferred;
• Enthusiastic, proactive, and down-to-earth work attitude, strong communication & execution ability, results driven, and a team player;
• Meticulous and strong sense of responsibility; able to handle stress and tight schedule;

How to Apply:

• Please send a comprehensive resume, a cover letter (If applicable), along with your current and expected salary and send to foongying@cordx.com or apply @ My Careerfuture.
• We regret that only shortlisted candidates will be contacted

We are a renowned food establishment in Chinatown and have plans to expand to food manufacturing and processing. We are looking for a passionate individual to lead the R&D and play a pivotal role in shaping the company’s future.

**Responsibilities:**

- Collaborate with cross-functional teams to develop and optimize chemical processes for food and beverage production.

- Design, implement, and monitor production processes, ensuring efficiency, quality, and compliance with regulatory standards.

- Conduct research and experimentation to enhance product quality, shelf life, and safety.

- Evaluate raw materials and ingredients to ensure compatibility and quality standards.

- Troubleshoot and resolve technical issues related to production processes and product quality.

- Stay abreast of industry trends, technological advancements, and regulatory requirements to drive continuous improvement and innovation.

**Requirements:**

- Bachelor's degree or higher in Food Science or Chemical Engineering or a related field.

- Solid understanding of food science and chemical engineering principles and their application in the F&B industry.

- Experience working in food manufacturing or a related field is highly desirable.

- Familiarity with food safety regulations and quality assurance standards.

- Strong analytical, problem-solving, and decision-making skills.

- Excellent communication and teamwork abilities. Ability to speak, read and write both English and Mandarin is essential.

- Candidates must be prepared to travel internationally for long periods.

About the company
This is an expansion role with our client who is seeking experienced life actuaries to manage the annuity portfolio.

About the job
Collaborate with various internal and external stakeholders, including consultants, government entities, to address actuarial related projects. Develop and refine actuarial processes and work-flows, including modelling, valuation, experience studies, risk monitoring, etc. Implement regulatory frameworks and industry standards for the business. Conduct research on actuarial methodologies, and utilize data analytics for actuarial analysis and supporting actuarial initiatives.

Skills and experience required
Degree in Actuarial Science with good progression in actuarial examinations with a recognised actuarial body, and has at least 3 years of actuarial work experience in the life insurance industry. You should possess good understanding of local regulatory framework, good analytical and problem solving skills. In order to succeed, you should posses excellent communication and stakeholder management skills.

To apply online please use the 'apply' function, alternatively you may contact Lynette Lim.

(EA: 94C3609/ R1435181 )

At Enact Mortgage Insurance (Nasdaq: ACT), we understand that there’s no place like home. That’s why we bring our deep expertise, insightful offerings, and extra mile service to work every day to help lenders put more people in homes and keep them there.

We’re looking for an Actuarial Leader in Raleigh, NC to join us in fulfilling our mission, while utilizing our values of excellence, improvement, and connection. In this role, you will report to the Chief Actuary and manage/support the process for valuing reserves. The ideal candidate is a strong communicator, self-motivated, detailed-oriented, and a highly organized individual who is capable of handling multiple tasks simultaneously while maintaining a high-quality work product. This position requires interactions with multiple functions, data analysis, strong understanding of company processes, utilizing accepted actuarial standards and methodologies, and incorporating knowledge gained through on-the-job experience for continual evaluation and improvement of the reserving process.

WHY WORK AT ENACT

• We bring innovative thinking to the situations at hand
• We seek out and incorporate diverse views to strengthen our outcomes
• We work on challenging and rewarding projects
• We offer competitive benefits:
  • Hybrid work schedule (shared in-office days Tuesdays – Thursdays)
  • Generous Time Off
  • 40 Hours of Volunteer Time Off
  • Tuition Reimbursement and Student Loan Repayment
  • Paid Family Leave and Flexible Spending Accounts
  • 401k with up to 5% employer match
  • Fitness and Emotional Wellness Reimbursements

LOCATION
Enact Headquarters, Raleigh, NC – hybrid schedule

WHAT YOU WILL BE DOING

• Manages and supports actuarial function in valuing reserves for the mortgage insurance product line

• Applies traditional actuarial reserving techniques to assess reserves and conduct reviews of loss results, past and current trends to project future losses

• Lead, coach, and develop a small team of high performing actuaries. Work with each team member to deliver high quality work within their core responsibilities, continually learn about our business and industry, and expand beyond the scope of their current roles

• Develops internal and external communications, including interactions with regulatory authorities and management that will describe and support reserve changes

• Supports the development/design of new models for reserving and forecasting purposes

• Displays proficient ability to analyze SAS datasets and modeling results and test for possible data biases and errors

• Creates and reviews documentation procedures and policy documents that ensure transparent and cohesive reserving process

• Incorporates and shares best practices regarding reserving models, techniques, and research with other functions within Enact

• Responds to questions from senior leadership, auditors, consultants, and other interested parties

WHAT YOU BRING

• Bachelor’s degree in actuarial science, mathematics, statistics, or related field

• Fellow of the Casualty Actuarial Society (FCAS)

• 7+ years in finance, risk, or actuarial functions, mostly focused on reserving.

• Excellent communications skills, particularly in a collaborative cross-functional team environment including senior leaders

• Strong planning, vision setting, and organizational skills with an ability to outline initiatives and develop priorities in support of that vision.

• Critical thinking and critical thinking skills

• Proficient ability to analyze data and develop recommendations

• Attention to detail, strong focus on accuracy and ability to review actuarial processes

PREFERRED QUALIFICATIONS

• Experience with machine learning and predictive modeling

• Computer programming knowledge (such as SAS, VBA, or other programming language)

• Previous leadership experience

COMPANY
Enact is a leading publicly traded U.S. private mortgage insurance provider, offering borrower-centric products that enable lenders and other partners across the U.S. to help people responsibly achieve and maintain the dream of homeownership.

By empowering customers and their borrowers, Enact seeks to positively impact the lives of those in the communities in which it serves in a sustainable way. Headquartered in Raleigh, North Carolina, we play an active role in supporting a healthier Triangle community. We also support our colleagues’ philanthropic efforts in their home communities across the U.S.

Enact values all perspectives, characteristics and experiences, and DEI remains at the forefront of what we do. We strive to create an environment where employees can bring their full, authentic selves to work to help each other and their customers.

We are proud to be an equal opportunity employer and all hiring decisions are based on merit, qualifications, and business needs. We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics.

About the Role:

This is a key role within the Convatec Technology & Innovation (T&I) team, a group that spends $100M+ annually to discover, design, build, and launch the products that will enable the company’s future success. As the R&D Portfolio Strategy Manager, you will play a key role in helping to set the strategic direction for the Convatec innovation and new product development portfolio. You will be a trusted partner across the T&I organization to help Convatec understand where to place strategic bets on new products to drive sustainable business results.

This role will report to the Director of R&D Portfolio Strategy and will work very closely with a wide range of internal stakeholders.

Duties & Responsibilities:

Set the direction for the Convatec T&I Portfolio

• Work with the Director of R&D Portfolio Strategy, CTO, and T&I Leadership Team to help set the investment priorities for the development of new products
• Suport the strategy development and prioritization of the entire Convatec portfolio of R&D, medical/clinical, and regulatory work through the development and use of various tools and KPIs
• Conduct analyses that will help the T&I team understand the value of the Convatec innovation portfolio and make key prioritization decisions
• Evaluate project investment scenarios, identify issues, develop hypotheses and communicate insights and recommendations to key decision-makers
• Support the Convatec Technology & Innovation (T&I) strategy plan
• Coordinate and drive the innovation portfolio planning process with the help of the Director of R&D Portfolio Strategy as well as a wide range of internal stakeholders
• Conduct research and analyses on a wide variety of internal and external-facing topics and make recommendations to help Convatec focus on the resources on the most valuable activities

Engage the T&I team to advance our strategy

• Work with team members across T&I and other functions to help drive the implementation of strategic initiatives and report out on progress to leadership
• Help R&D project teams develop and review project business cases that will yield optimal return for Convatec. Review business cases with T&I leadership team and executive team to validate project viability and prioritization
• Work with Finance to ensure that our overall portfolio strategy is consistent with available resources and support the creation of investment scenario analyses
• Proactively engage innovation project teams to understand progress and update portfolio planning analytics as needed
• Facilitate discussions between the T&I team and business unit finance business partners to ensure that our innovation portfolio will meet business unit financial ambitions

Engage executive leadership

• Work with T&I leadership to develop report-out materials for periodic review by executive leadership, including CEO, CFO
• Support the production of communication materials for the Board of Directors
• React to executive-level feedback with timely and thoughtful analyses and recommendations

Serve as a leader within Convatec

• Build relationships with the T&I stakeholders in many functions, including R&D, medical/clinical, and regulatory, as well as with other stakeholders across Convatec, including Marketing, Finance, and Corporate Development / Corporate Strategy, to understand the key portfolio needs for Convatec, drivers of success, and risks to our new product development plans
• Help drive principles of analysis-based portfolio planning across the broad Convatec T&I community

About You:

Skills & Experience:

• Strategic, analytical, and critical thinking abilities
• Ability to conduct research and analyses, understand interactions between multiple factors, develop recommendations, and communicate insights to stakeholders
• Competency in developing executive communication materials, e.g., PowerPoint, white papers
• Ability to work and communicate with a wide range of functional stakeholders
• Ability to see the “big picture”, with attention to detail where necessary
• Financial modeling capabilities, including DCF modeling, NPV/IRR analysis, and scenario modeling
• Industry experience in Medtech, Pharma, or other Life Sciences is a plus

Education/Qualifications:

• Undergraduate degree, preferably in engineering, math, or science discipline
• Minimum of 5+ years' total experience with experience in corporate strategy and/or project-based finance
• Strategy consulting background (3+ years)

Working Conditions:

• Hybrid schedule
• Location: within a commutable distance to Lexington, MA / greater Boston area
• Position may require travel up to 15% within Europe or U.S.

Our products make a big difference every day. So will your contribution. The work you do will mean more, because it’ll make things better for your team, our business or our customers’ lives. It’ll inspire you to deliver to your very best. And we’ll be right behind you when you do.

This is a challenge more worthwhile.

This is work that’ll move you.

#LI-MH1

#LI-Hybrid

Beware of scams online or from individuals claiming to represent Convatec

A formal recruitment process is required for all our opportunities prior to any offer of employment. This will include an interview confirmed by an official Convatec email address.

If you receive a suspicious approach over social media, text message, email or phone call about recruitment at Convatec, do not disclose any personal information or pay any fees whatsoever. If you’re unsure, please contact us at careers@Convatec.com.

Equal opportunities

Convatec provides equal employment opportunities for all current employees and applicants for employment. This policy means that no one will be discriminated against because of race, religion, creed, color, national origin, nationality, citizenship, ancestry, sex, age, marital status, physical or mental disability, affectional or sexual orientation, gender identity, military or veteran status, genetic predisposing characteristics or any other basis prohibited by law.

Notice to Agency and Search Firm Representatives

Convatec is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Convatec employee by a third party agency and/or search firm without a valid written and signed search agreement, will become the sole property of Convatec. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.

Already a Convatec employee?

If you are an active employee at Convatec, please do not apply here. Go to the Career Worklet on your Workday home page and View "Convatec Internal Career Site - Find Jobs". Thank you!

Tissue Diagnostic Science Manager

12 Month Fixed Term Contract or Secondment

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us.

With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing ground breaking science with the latest technology to achieve breakthroughs. Backed by investment, we are seeking to deliver 6 new molecular entities by 2025.

A place built on courage, curiosity and collaboration - we make results-oriented decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team.

Pioneers of collaborative research we have built an outstanding scientific community both internally and externally. Fusing academia and industry, we have united some of the world's foremost medical centres.

Have the opportunity to build an exciting and meaningful career as part of the team committed to improving the lives of millions with cancer.

Precision Medicine and BioSamples within AstraZeneca focuses on matching medicines to those patients who will benefit from them most and delivers companion or complementary diagnostic assays that align with the drug development process and enable personalised healthcare approaches within our clinical portfolio.

As a Manager, Tissue Diagnostics Science you will use your knowledge of tissue based diagnostic assays including immuno-histochemistry (IHC), in situ hybridization (ISH) and other ground breaking technologies and approaches (multiplexing, multi-immunofluorescence, Digital pathology and artificial intelligence etc.) to provide scientific and technical expertise to deliver innovative tissue diagnostic approaches to AstraZeneca's clinical portfolio, through strategic partnerships with leading diagnostic companies.

If successful, you would be part of multidisciplinary teams implementing and delivering diagnostic tests to match the right patients to the right drugs. Specifically, you would be:

• Delivering diagnostic testing to clinical studies as agreed with project leaders including tissue (IHC, ISH assays) diagnostic test establishment in partner laboratories, establish innovative diagnostic tests (e.g. tests relying on machine learning/AI), monitor diagnostic test data for quality control, provide scientific troubleshooting when necessary and preparation of study reports with presentation at appropriate meetings.
• Accountable for the operational, scientific and regulatory aspects of establishing and controlling diagnostic tests used to identify patients who are eligible to enter drug clinical trials.
• Performing technical due diligence of potential external partners (e.g. start-up companies, diagnostic manufacturers, laboratories) in scientific area(s) of expertise.
• Leading projects across internal and external partners in a global multi-disciplinary environment, applying scientific, technical and operational expertise.
• Accountable to scout and evaluate emerging technologies in your area of expertise aligned with mid and long term strategic priorities of Precision Medicine.
• Identify opportunities, propose solutions and work across boundaries in the scientific area(s) of expertise that will enable drug development projects and diagnostics labelling.
• Generating scientific evidence from a variety of data-types (e.g. images, real-world evidence, clinical trial data) to enable companion diagnostic test selection, regulatory submissions and diagnostic test life-cycle management.
• Delivering diagnostic data work packages to enable regulatory submission and approval inclusive of studies to enable market adoption and life cycle management, including statistical data analysis.
• Building and maintaining a knowledge of current and emerging diagnostic technologies in area of expertise.
• Accountable for the delivery of scientific evidence enabling the development of new diagnostic tests, their regulatory submissions and commercial launches.
• Driving continuous improvement in the scientific area(s) of expertise, aligned to Precision Medicine strategic objectives of increasing project success, adding value to projects and delivering better medicines to patients.
• Being accountable for the time and quality of agreed work.
• Providing updates on the progress, risks and opportunities of the agreed work to the appropriate governance bodies for review, challenge and issue resolution.
• Taking on small supervisory or skills transfer / training roles

Essential Minimum

• BSc or equivalent experience in relevant subject
• Experience of working in collaborative or multi-functional initiatives
• Excellent verbal and written communication skills
• Knowledge of tissue-based biomarker assays, such as immunohistochemistry (IHC) and/or in situ hybridisation (ISH), including troubleshooting and QC
• Operational experience of clinical trial set up, documentation and QC / monitoring of tissue testing

Desirable

• Advance degree or equivalent experience in a relevant area
• An understanding of clinical and diagnostic development and commercialisation.
• Knowledge of clinical testing procedures and applicable laboratory testing regulations such as Good Clinical Practice, CAP/CLIA, Good Clinical Practice and Quality Systems Regulation.

Why we love it

If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Here we truly understand science and apply it every day to strengthen and grow our pipeline.

This role can sit at our UK, Cambridge or Poland, Warsaw locations

Cambridge Biomedical Campus (1 position); Warsaw, Poland (1 position)

Competitive Salary & Benefits

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en