Total 22 job vacancies by Guys and St Thomas NHS Foundation Trust

An opportunity has arisen for an experienced and dynamic nurse leader to lead and manage the Vaccine and Trials Team and Infection Research Team.

The position is full-time (37.5 hours per week) and is a one year fixed-term contract that can be applied to as a secondment.

The successful candidate will be an expert research nurse with proven leadership skills, flexibility and excellent organisational skills. You will be supported by Head of research Workforce, R&D leads and leaders within the directorate as well a network of Research Matrons and Managers.

The post holder will lead and line manage 2 research teams, one in the Directorate of Infection and the other is the Vaccine and Trials Team within the Directorate of Research and Development.

Duties include:
• Visible professional and clinical leadership for clinical research delivery staff.
• Ensuring the highest standard of patient care, good clinical practice standards
• Ensuring excellent performance on delivery of whole research portfolio
• Being an expert resource and facilitator for researchers and the research delivery teams

Please see job description for detailed information on duties.

Guy’s and St Thomas’ NHS Foundation Trust comprises five of the UK’s best-known hospitals – Guy’s, St Thomas’, Evelina London Children’s Hospital, Royal Brompton and Harefield – as well as community services in Lambeth and Southwark, all with a long history of high-quality care, clinical excellence, research and innovation.

We are among the UK’s busiest, most successful foundation trusts. We provide specialist care for patients including heart and lung, cancer and renal services as well as a full range of local hospital and community services for people in Lambeth and Southwark.

We have a long tradition of clinical and scientific achievement and – as part of King’s Health Partners – we are one of England’s eight academic health sciences centres, bringing together world-class clinical services, teaching and research.

We have around 22,700 staff, making us one of the largest NHS Trusts in the country and one of the biggest employers locally. We aim to reflect the diversity of the communities we serve and continue to develop new and existing partnerships with local people, patients, neighbouring NHS organisations, local authorities and charitable bodies and GPs.

We strive to recruit and retain the best staff as the dedication and skills of our employees lie at the heart of our organisation and ensure that our services are of the highest quality, safe and focused on our patients.

Please see the attached job description for a detailed description of the clinical, managerial, governance, professional, research and education aspects of the role


This advert closes on Sunday 1 Dec 2024

The post holder will act as patient and participant advocate at all times, the post holder will be expected to co-ordinate research clinics and organise study related care. They will implement and evaluate strategies to identify and assist in the enrolment of research participants.

The post-holder will lead on a portfolio of research studies and perform a range of clinical assessments in line with accepted standards of practice. They will communicate proactively with the study and clinical teams to ensure good participant experience and adherence to study protocols. The post holder will be responsible for case report form completion, site file management, implementation of amendments and maintenance of databases. They will act as mentor and support for new and junior team members. They will contribute to quality assurance processes within the team. The post holder will ensure the well-being of participants by adhering to study protocols, relevant regulations and local Standard Operating Procedures (SOPs).

Guy’s and St Thomas’ NHS Foundation Trust comprises five of the UK’s best-known hospitals – Guy’s, St Thomas’, Evelina London Children’s Hospital, Royal Brompton and Harefield – as well as community services in Lambeth and Southwark, all with a long history of high-quality care, clinical excellence, research and innovation.

The Gastrointestinal Medicine and Surgery research team delivers studies across the multidisciplinary gastrointestinal department. The team is made up of Principal Investigators and Sub-investigators, Research Nurses and Clinical Research Practitioners who work together to deliver studies to high standards across both Guy’s and St Thomas’ hospital sites.

Clinical and Communication Responsibilities
• Provide excellent customer care skills to ensure patients and participants come first.
• Work within relevant regulations and ICH GCP (International Conference on Harmonisation and Good Clinical Practice) ensuring that the clinical trial protocol is adhered to at all times.
• Lead on a portfolio of trials and coordinate participation. This requires liaising with the clinical team to organise and ensure that trial specific investigations are undertaken according to the protocol, paying particular attention to accurate data collection and dissemination and version control of essential documentation.
• Devise, implement and evaluate strategies for recruiting participants into clinical studies and identify individuals potentially eligible for research studies. Gain permissions for research contacts.
• For specific studies post holder may be delegated to obtain consent from participants in line with Trust policy and research protocol.
• Organise and facilitate participant appointments and follow-up phone calls.
• Accurately perform and record observations of clinical activities required according to personal competencies and the study protocol and obtain the results including blood pressure, temperature, respirations, questionnaires, urinalysis, weight and height, and report abnormalities or changes appropriately.
• Report any adverse events or health concerns which occur whilst the participant is taking part in the study to the appropriate doctor or nurse in a timely manner, and to the appropriate principal or co-investigator.
• Liaise with pharmacy to co-ordinate the availability and dispensing of study drugs if appropriate.
• Perform tasks requiring clinical and laboratory skills, including phlebotomy, venepuncture, tissue and blood sample preparation within clinic and laboratory in line with personal competencies and approved study protocol
• Process biological samples according to personal competencies and the study-specific protocol and laboratory manual and organise the storage, shipment and documentation of samples.
• Provide ongoing support to the participant and carer whilst participating in the clinical study.
• Communicate study related information effectively with the research team and study participants and their family members. This information may be complex or sensitive, and there may be barriers to understanding.
• Communicate effectively and efficiently specialised advice pertaining to research protocols to members of the multidisciplinary team.
• Engage effectively with other departments and wards at the site/s, in order to promote a good working environment, integration of research and open channels of communication.
• Communicate with external study coordinators and sponsor representatives, nationally and internationally.
• Attend and participate in departmental meetings and help promote new ideas and methods and assist in their implementation.
• Attend and participate in multidisciplinary team meetings.
• Arrange, attend and record minutes for research and other relevant departmental meeting.
• Attend national and international study specific meetings and disseminate information to members of the multi-disciplinary team as required.

Information and data management
• Update participant study and medical records to accurately document study related activity and procedures.
• Ensure the confidentiality of verbal, written and computerised information.
• Complete case report forms in a precise and timely manner, ensuring that all the relevant clinical data in the participant’s medical notes and study file is transcribed accurately.
• Responsible for the maintenance of the Investigator Site Files.
• Aid with local study set up to ensure all applicable documents are ready to use once relevant approvals are received. Organise study set up visits, involving all relevant departments.
• Create databases, validate and maintain them and ensure their security and compliance with the data protection act.
• Update and maintain centralised database.
• Responsible for ensuring that all data queries are dealt with in a timely and efficient manner.
• Assist in the creation and maintenance of good office systems for the smooth running of the service.
• Plan, prepare documentation and participate in audit and monitoring visits.
• Implement strategies to ensure full and accurate data-set for all study participants.
• Process amendments according to standard operating procedure as received in a timely manner.
• Collate data and compile reports for the Clinical Lead, Research Managers and commercial sponsors as required.
• Provide timely information and reports to reflect recruitment of patients including timely entry to EDGE according to team processes.

Management and leadership
• Provide advice and training to colleagues as relevant to your role.
• Supervise, train or mentor new or more junior staff as required.
• Act as a role model, giving guidance, counselling and support to new and junior staff.
• Actively contribute to the teaching programme within the department.

Education and Professional development
• Take responsibility for identifying personal training and educational needs within the context of the service and those identified during the appraisal process.
• To maintain an up to date knowledge relevant to the specialty and research.
• Act in accordance with the Health Education England (HEE) Care Certificate framework standards at all times.
• Undertake an Individual Performance Review annually with your Line Manager.
• Maintain a record to reflect any training carried out pertaining to the post.

Other responsibilities
• Act always in a manner which, promotes positive working relationships and maintains the professional image of the Trust.
• Responsibly manage the control of equipment, resources and stock.
• Actively seek to develop the role to take account of changing requirements of the service.
• Ensure own actions help to maintain quality.
• To work as a member of a multi-disciplinary team.
• Work collaboratively with colleagues across R&D and wider GSTFT to facilitate the achievement of objectives and shared learning.


This advert closes on Monday 2 Dec 2024

Are you someone who can easily adapt to different settings, enjoy meeting new people, and would like to make a difference in health and social care through clinical research?

South London Regional Research Delivery Network (RRDN) is looking for an enthusiastic Research Nurse to join the Agile Workforce team.

The Research Nurse will play a key role in ensuring that any research undertaken within the Care settings department safeguards the wellbeing of the patients and is conducted according to Good Clinical Practice (GCP) and the Medicines for Human Use (Clinical Trial) Regulations 2004 and Amended Regulations 2006.

Working collaboratively with the clinical trials team and the wider multidisciplinary team in the management of research patients. They will also act as a patient advocate providing support and assistance as required and assist in the coordination and management of a portfolio of clinical research studies.

The post holder will be required to work flexibly across sites within the RDN: South London geography. The employing Trust will be Guy’s and St Thomas’ NHS Foundation Trust.

If applying as a registered nurse you must have appropriate UK professional registration.

The post holder will be responsible for delivering an agreed number of portfolios of clinical trials within the Secondary, Primary Care and Community settings across the South London region. They will work flexibly across the disciplines to ensure the success of the clinical research projects they are assigned to. The Research Nurse will play a key role in identifying opportunities to broaden the current portfolio.

The applicant must have considerable experience of working independently and have excellent organisational and time management skill.

The National Institute for Health Research (NIHR) is the nation's largest funder of health and care research. The NIHR:

● Funds, supports and delivers high quality research that benefits the NHS, public health and social care

● Engages and involves patients, carers and the public in order to improve the reach, quality and impact of research

● Attracts, trains and supports the best researchers to tackle the complex health and care challenges of the future

● Invests in world-class infrastructure and a skilled delivery workforce to translate discoveries into improved treatments and services

● Partners with other public funders, charities and industry to maximise the value of research to patients and the economy

The NIHR was established in 2006 to improve the health and wealth of the nation through research, and is funded by the Department of Health and Social Care. In addition to its national role, the NIHR supports applied health research for the direct and primary benefit of people in low- and middle-income countries, using UK aid from the UK government.

● Carry out planned care required by the clinical trials protocol for a group of volunteers without direct supervision
● Ensure the assessment, planning, implementation and evaluation of evidence based, individualised patient/volunteer care.
● Responsible for recruiting to, and following up, patients within studies. This includes both randomised clinical trials and other high quality clinical studies. The role will involve working closely with multidisciplinary clinical teams
● Act as a patient advocate enabling patients to make informed choices concerning their involvement in the clinical trials and ensuring advice and information is provided.
● Ensure there is sufficient skill mix of staff for patient safety during clinical trials and ensuring that they are carried out within the Trust and Centre's policies and clinical trial protocol.
● Assist in clinical trials including venepuncture of volunteers when necessary ensuring that they are carried out within the Trust’s policies, research governance, Medicines for Human Use (Clinical Trials Regulations) Regulations 2004 and Amended Regulations 2006 Incorporating International Conference on Harmonisation of Good Clinical Practice (ICH GCP) Data Protection Act and Human Tissue Act.
● Undertake clinical tasks such as phlebotomy, analysis of blood specimens, drug administration and clinical observation etc.
● Assist and advise staff, both registered and unregistered in the delivery of care to the volunteer.
● Ensure that written informed consent has always been obtained for any treatment provided for, or any sample or data taken from a Volunteer which will form part of a research study, in accordance with the Trust research governance arrangements and Medicines for Human Use (Clinical Trials Regulations) Regulations 2004 and Amended Regulations 2006. Incorporating International Conference on Harmonisation of Good Clinical Practice (ICH GCP)
● Have responsibility for the correct administration and custody of medicines according to Trust policy.
● Maintain all data and case report forms relating to clinical trials in accordance with the Medicines for Human Use (Clinical Trials Regulations) Regulations 2004 and Amended Regulations 2006 Incorporating International Conference on Harmonisation of Good Clinical Practice (ICH GCP) and the Research Governance Framework.
● Report any deviation from normal practice to senior staff and implement agreed changes in care programme.
● Deal with concerns raised by volunteers and visitors in a proactive manner and take remedial action as necessary.
● Act as the volunteers’ advocate.

Administration

● Plan and organise workload in order to meet studies and volunteer needs.
● Ensure that nursing practices comply with Trust policies and procedures
● Communicate effectively at all times and maintain a harmonious working environment.
● Maintain a safe environment in accordance with the Health and Safety at Work Act.
● Assist managers and senior nurses/practitioners in managing incidents, accidents and complaints in accordance with Trust policies and procedures.
● Assist in ensuring the availability of resources for volunteer care
● Ensure equipment is in good working order, and report appropriately when defective
● Participate in audits, EG those undertaken by the Medicines and Health Care Regulatory Authority (MHRA) nursing audits and clinical benchmarking exercises and suggest any change to improve standards
● Ensure the economical use of resources
● Contribute to the overall RDN CRN or departmental budget by identifying areas where cost improvements can be made
● Ensure the safe custody of volunteer’s property in accordance with Trust policies.
● Actively participate in and support the development of the clinical research facility.
● Promote and participate in the implementation of policies within the Centre and to ensure compliance with Trust, Government and EU Directives.
● Maintain accurate documentation in clinical trial documents and patient notes.
● Ensure that clinical trials are effectively archived as required.
● Assist in the process of gaining local regulatory committee approval (ethics and R&D approval).

Other

● Understand and adhere to Trust policies and procedures.
● To maintain patient confidentiality and standards of Good Clinical Practice (GCP) at all times.
● Maintain NMC registration


This advert closes on Sunday 24 Nov 2024

We are one of the largest cardiac MRI scanning centres in the UK. Our Imaging Clinical Research Facility is based in our St Thomas Hospital campus with strong research collaboration focusing on the development of novel acquisition, reconstruction and motion correction using different field strength MRI scanners. The facility is run by King’s College London, the University partner in close partnership with Guy’s & St Thomas’ NHS Foundation Trust. Clinical services are delivered to approximately 13,000 patients a year (Cardiac MRI, Perinatal MRI and the PET Centre), and were recently re-accredited in accordance with the Quality Standard for Imaging (QSI) 2021

We are looking for an experienced and enthusiastic Cardiac MRI Radiographer to join our nationally accredited clinical research imaging team. The department supports and mentors Radiographers in their personal and professional development including actively encouraging staff to attend high profile national and international seminars, conferences, presenting posters, abstracts and presentations.

We have a reputation for clinical excellence and high quality teaching and research. We are part of King’s Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King’s College London we have dedicated clinical research facilities and a National Institute for Health Research (NIHR) Biomedical Research Centre.

The main purpose of this post is to participate as a member of a multidisciplinary team within our Cardiovascular Imaging Department to deliver an efficient, effective and timely Cardiac MRI service, supporting a strong portfolio Clinical Research Imaging programmes run by the Imaging Clinical Research Facility.

The successful candidate will work with clinicians, researchers and biomedical engineers whilst performing excellent quality imaging studies in accordance with the departmental protocols.

Guy’s and St Thomas’ is among the UK’s busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

In February 2021 the Royal Brompton and Harefield joined Guy’s and St Thomas’ NHS Foundation Trust, bringing together world-leading expertise in the care and research of heart and lung disease.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS.

The commitment of our 23,500 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

The job description attached provides the detail summary of main duties and responsibilities of the job.


This advert closes on Sunday 3 Nov 2024

An opportunity has arisen for a Band 6 Children’s Clinical Research Nurse, on a 12-month fixed term basis, to join our dynamic and friendly Paediatric Genetics Research team to support and lead on the delivery of high quality, holistic care to children and young people participating in paediatric genetics research studies. Evelina London is the first children’s hospital to be rated as outstanding by the Care Quality Commission (CQC). The paediatric clinical research team continues to work to this level of excellence and all team members will have the opportunity to contribute to this work.

As a Children’s Research Nurse you will be working with the wider multidisciplinary team across commercial and non commercial studies to deliver a seamless pathway for patients participating in research trials/studies.

You will be responsible for the holistic nursing care of children / young people and their families on existing and new clinical trials and contribute to the assessment and management of their care pathways.

This will involve leading on study set up activities, screening, recruiting, educating and monitoring children and young people in studies as well the collation and documentation of study data. You will be trained to take informed consent for selected studies which do not involve a medicinal product.

We provide a comprehensive induction programme and actively encourage opportunities to develop new clinical and leadership skills . The normal working hours for the post is Monday - Friday 9am- 5pm although flexibility may be required accommodate patient visits and assessments outside of these hours.

Guy’s and St Thomas’ NHS Foundation Trust comprises five of the UK’s best known hospitals – Guy’s, St Thomas’, Evelina London Children’s Hospital, Royal Brompton and Harefield – as well as community services in Lambeth and Southwark, all with a long history of high quality care, clinical excellence, research and innovation.

We have a long tradition of clinical and scientific achievement and – as part of King’s Health Partners – we are one of England’s eight academic health sciences centres, bringing together world-class clinical services, teaching and research.

We have around 22,700 staff, making us one of the largest NHS Trusts in the country and one of the biggest employers locally. We aim to reflect the diversity of the communities we serve and continue to develop new and existing partnerships with local people, patients, neighbouring NHS organizations, local authorities and charitable bodies and GPs.

We strive to recruit and retain the best staff as the dedication and skills of our employees lie at the heart of our organization and ensure that our services are of the highest quality, safe and focused on our patients.

Comprehensive information is provided on the role and requirements within job description and person specification.


This advert closes on Wednesday 30 Oct 2024

We have an opportunity for a Research Coordinator to join our unique respiratory team at GSTT. Our research programme is at the heart of everything we do at Guy’s and St Thomas’ NHS Foundation Trust, and plays a vital role in helping us to consolidate and grow on our position as one of the UK’sleading research Trusts.

This is a unique opportunity for a Research Coordinator to help grow the clinical trials service both in terms of volume and quality and support a novel multi-site study for patients with COPD.

The post holder will be involved in ensuring that any research undertaken within the department safeguards the wellbeing of the patients and is conducted according to Good Clinical Practice (ICH GCP), Medicines for Human Use (Clinical Trial) Regulations 2004 and Research Governance Framework.

The post holder will support the senior trials manager and RAPID trials manager to ensure the smooth day to day running of this novel multi-site research study.

Guy’s & St Thomas’ (GSTFT) has been appointed host organisation for the LCRN in South London (South London CRN). Guy’s and St Thomas’ is one of the largest hospital trusts in the country, with an annual turnover of more than £1.2 billion; 2 million patient contacts a year, and employing 13,200 staff. Our hospitals have a long and proud history, dating back almost 900 years, and have been at the forefront of medical progress and innovation since they were founded. We continue to build on these traditions and have a reputation for clinical, teaching and research excellence.

We provide a full range of hospital services for our local communities and - from April 2011 – have integrated community services in Lambeth and Southwark into the Trust. We also provide specialist services for patients from further afield, including cancer, cardiac, kidney, women’s and orthopaedic services, and we are home to the Evelina Children’s Hospital. Seewww.guysandstthomas.nhs.uk.

As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends. We also have a positive approach to corporate social responsibility and are keen to engage our staff in an agenda that ranges from promoting environmental sustainability to the creation of local employment opportunities.

The post holder will be responsible for ensuring that the Study achieves its recruitment goals for a range of research studies by actively aiding clinical staff in enlisting patients. Additionally, the post holder will facilitate other site activities, which include coordinating site visits, managing intervention follow-ups, entering data, overseeing database operations, and organising protocol training as required.

The post holder will collaborate closely with a dynamic, multidisciplinary research team to execute this portfolio study.


This advert closes on Sunday 13 Oct 2024

The Royal Brompton cystic fibrosis (CF) clinical trials department comprises of clinicians, academics, allied health professionals and admin/ finance members. The Brompton adult & paediatric CF centres are made up of world leading teams carrying out global, multicentre interventional and observational studies, in both adults and children, being led by Profs Davies, Simmonds and colleagues. The Brompton is the lead site for an early-phase, multicentre trial of CFTR gene therapy led globally by Prof Eric Alton; this post has been created primarily to support this trial, whilst also working alongside the team across the CF trials portfolio.

You will be responsible for all matters relating to data collection/management, involving direct patient interactions and provision of administrative support for trial-related activities for the gene therapy study. This role requires the post holder to be able to handle a varied/extensive workload. Training will be provided in all aspects of the role.

You will support the other research taking place within the CF trials department, based at the Royal Brompton campus, close to the vibrant King’s Road, Chelsea. You will be located in an office with a multidisciplinary clinical and research team allowing for networking/learning from other healthcare professionals. We encourage/support applicants in applicable career progression as a clinical research practitioner/research nurse including attendance at courses, seminars/conferences.

Identify/recruit participants for research studies in CF/other inherited respiratory conditions
• Frontline support to study participants by phone/in clinic. Demonstrate politeness, courtesy & sensitivity. Ensure enquiries are dealt with/followed up.
• Performance & review of clinical assessments, collection/processing of participants blood or other samples
• Maintain accurate/complete records. Always demonstrate awareness/compliance with local policies, procedures, guidelines/standards
• Maintain up-to-date skills/knowledge in the field of CF/clinical trials. Attend national/international conferences continuing professional development. Develop areas of personal interest in healthcare
• Contribute in the writing of research reports/publications

Essential:

Educated to degree level in a healthcare/science-related subject or have a Professional Nursing Qualification with valid NMC registration
• Experience of working directly with patients/ study participants in a clinical setting

Good understanding of clinical terminology
• Proven experience of organisational/record keeping/time management skills. Accurate data management, knowledge of handling confidential information. An understanding of current legislation/requirements

Excellent written & oral communication skills. Computer literate.
• Work independently, effectively & flexibly as part of a team-unit. Cooperate in the accomplishment of departmental goals/organisational objectives

Trust mission

To be the leading national and international centre for the diagnosis, treatment and care of patients with heart and lung disease, creating and disseminating knowledge through research and education

Patient care

Your primary concern will be to maintain patient safety during the conduct of clinical studies. The post holder will be responsible for:
• Coordination and facilitation of clinical research projects, managing them to the relevant standards.
• Screening of case notes for recruitment of appropriate candidates and discussing with patients about the opportunity to join a relevant study.
• Coordinating and supporting medical, nursing and technical staff to successfully complete research projects and the execution of clinical trials
• Participation in the execution of clinical studies taking patient samples, testing prototype medical equipment, performing analysis on patient samples
• Facilitating the research study process including scheduling patient admissions and undertaking the relevant patient assessment, investigations and treatment in accordance with the studies protocol
Being the point of contact for study participants, giving advice on the relevant study and correlated health issues
• Ensuring that nursing/ multidisciplinary team (MDT) documentation is maintained to the Trust and GCP standards
• Introducing improved systems of research conduct and management to enable successful project delivery
• Ordering and purchase of equipment using online systems including interaction with University based staff and systems
• Trust-wide clinical research polices and protocols, insuring their implementation
• Analyse research data, ensuring consistency and accuracy. Identify key errors in data collection/entry and address or flag as necessary
Identify system errors in bespoke data management systems (e.g. electronic case report forms) and provide feedback to the respective team and study nurse
• Address recurrent data queries which may highlight system problems or data collection issues
• Assist with ensuring that study equipment has the ability to download information as required by the study protocol

During research visits, specific duties will include, although not exclusively consist of:
• Height and weight measurements
• Collection of vital signs
• Recording adverse events and changes in medication
• Performing lung function, ECGs and sweat tests
• Sputum induction and sample collection
• Collection of breath samples
• Obtain blood samples by venesection
• Administration of Quality of Life questionnaires
• Supervision of study drug dosing

Training will be provided as needed in all of the above procedures.

Communication
• Arranging and attending team meetings
• Writing and circulating summaries of monthly meetings as requested
• Have an active email account and share information appropriately
• Document all adverse incidents as required by study protocols
• Report to local, national and international project partners as required
• Report on the technical and clinical performance of the studies as required
• Participate in local, national and international meetings

People management

Coordinate the participation of nursing, practitioner and medical staff to ensure the trials are completed within the project timetable

Ensure that they themselves and others involved in a study have the correct training to undertake the procedures. Ensuring that they and the team are up to date with their mandatory training

Organise own work on an ongoing basis, arranging one-off or recurring events, including training, Site Initiation Visits and Monitoring Visits

Policy and Service Development

You will be responsible for maintaining trial data to the relevant standards required for the study. This will include:
• Maintaining Trial Master Files to Medicines and Health Regulatory Authority (MHRA) standards
• Maintaining Investigator Site Files
• Collating source data
• Electronic reporting of trial data
• Checking, filing and monitoring patient consent forms
• Creating systems for data gathering and trial conduct such as standard operating procedures (SOPs)
• Entering data onto database
• Aiding statistical analysis
• Implement the trust policies & protocols within the department

In conjunction with the lead investigator for each project and/or the senior team, you will assist with writing and make available all SOPs, policies and guidance notes that will be needed by the research team to ensure the safe conduct of the clinical trials. Trial SOPs will conform to all relevant Policies such as Infection Control, Data Protection, Human Tissue Act.

Resource management
• Manage an inventory of consumables and equipment required for specific studies
• Record the use of any materials expended by the group in the conduct of the trials
• Purchase any additional equipment needed to conduct trials
• Report expenditure accrued in the conduct of clinical trials
• Arrange reimbursement of expenses to patients participating in research studies
• To attend relevant meetings
• To undertake any necessary training and/or development

Information management

Further sections
• To ensure all mandatory training courses such as Manual handling, Fire, Resuscitation, health and safety are attended on an annual basis and the knowledge gained adhered to.
• To abide by the Trust’s core behaviours for staff and all other Trust policies including standing financial instructions, research governance, clinical governance, patient and public involvement, codes and practices, and health and safety policies
• This job description is intended as a basic guide to the scope and responsibilities of the post and is not exhaustive. It will be subject to regular review and amendment as necessary in consultation with the post holder.


This advert closes on Tuesday 8 Oct 2024

Are you a dynamic, patient-centered, and self-motivated individual looking for a new and exciting challenge? We have a great opportunity for a highly motivated Clinical Research Practitioner to join us at the National Institute for Health Research (NIHR) Clinical Research Facility (CRF) at Guy’s and St. Thomas’ NHS Foundation Trust.

This position will offer the post holder an opportunity to work closely with experienced clinical and research colleagues across a diverse portfolio of trials covering over 20 different clinical specialties including but not limited to HIV, Sickle cell disease, Diabetes, Dermatology, Nephrology and Oncology.

You will be working within a highly regulated environment of clinical research. With our MHRA Phase I accreditation of our Guy’s Unit you will contribute to team-wide improvement projects designed to ensure we maintain our accreditation status. Accordingly, you will also gain experience in quality improvement, quality assurance, monitoring, audit and inspection.

To meet the needs of the service you will be required to work at two of our Units – the Guy’s Phase I Unit and the St. Thomas’ Adults Unit.

The post holder is expected to work on shift patterns necessary to ensure patient safety and timely delivery of clinical trials.Work patterns will include day shifts, regular late and night duties, and weekends as required.Your work patterns will be agreed with your Line Manager and align with the weekly duty roster of both Units.

The post-holder will be allocated to support/lead a selection of trials and studies. The successful candidate will undertake clinical, laboratory and study management duties while ensuring patient safety and complying to Good Clinical Practice (GCP) Guidelines.

Candidates who have initiative, effective communication, and team work skills and clinical research experience are encouraged to apply.

Example of duties include but not limited to:

Clinical: phlebotomy, taking observations, recording ECGs and cannulation

Laboratory: processing, storing and shipping samples

Study management: co-lead/lead on portfolio of trials, completing eCRF/CRFs, data query resolution, ISF maintenance, coordinating patient visits and trial assessment activities, reporting of AE/SAEs, liaising with internal and external CRA/sponsors/R&D, attending Study Initiation Visits, and hosting Monitoring Visits.

The National Institute of Health Research (NIHR) Clinical Research Facility (CRF) for Experimental Medicine at Guy’s and St Thomas’ NHS Foundation Trust provides state of the art facilitates and world-leading expertise to support the NHS, universities and industry in conducting ground breaking experimental medicine studies.

The CRF is comprised of five units located across our sites – Guy’s CRF incorporating our phase I unit; St Thomas’ CRF with a unit focus on experimental and cardiometabolic research; our Imaging CRF, built around patient pathways across St Thomas’ Hospital, the Children’s CRF located within Evelina London Children’s Hospital, and the Royal Bromptom CRF. Being located across three sites in the heart of London provides us with access to the most diverse populations in the UK.

With MHRA Phase I accreditation for our Guy’s CRF unit, we are uniquely placed to deliver Phase I commercial and non-commercial patient focused studies. Our CRF is the only one in the UK with embedded Advanced Therapies Manufacturing (GMP) and immune monitoring platforms.

Please refer to the attached job description and person specification which outlines the full and detailed responsibilities of this role. More information can be gained from contacting us on the details below.






This advert closes on Sunday 29 Sep 2024

We are seeking to appoint a Research Development Officer to the Research Office of the Heart, Lung and Critical Care (HLCC) Clinical Group of Guy’s and St Thomas’ NHS Foundation Trust. The Research Development Officer will play a key role in delivering the Trust’s service for research development, assisting, and facilitating HLCC Clinical Group researchers in their research endeavours, thereby supporting the Trust to develop and grow its research business. The post is hybrid, working 2 to 3 days per week on site and working across our four hospitals (Royal Brompton Hospital, Harefield Hospital, Guy’s Hospital, St. Thomas’ Hospital) as required. Part-time working will be considered for the right candidate.



Shortlisted candidates will be notified on or before Monday 14th October with interviews expected planned for Tuesday 22nd October.

Applications which use AI assistance to support the completion of their supporting statements will be rejected.

The post holder will assist the Research Development Team by providing pre-award support on commercially funded research grants, providing administrative assistance, including costing and guidance in the development and submission of funding applications. They will also assist the Research Development Team in raising the profile of research internally and externally through various events and campaigns, highlighting the support of the Research Office to research staff and communicating research funding and training opportunities.

The R&D Department at Royal Brompton and Harefield Hospitals is part of the Guy’s & St Thomas’ NHS Foundation Trust (GSTFT). It supports the Heart Lung and Critical Care Clinical Group research and innovation activities. HLCC is one of 4 Clinical Groups at GSTFT. The role is based at Royal Brompton Hospital but travel to other sites will be a necessary part of the role. The team support a broad portfolio of research projects across the breadth of cardiac, respiratory and critical care medicine.

Assist researchers within HLCC in the preparation of commercially funded research grants.



Facilitate post-award and project set-up processes, ensuring funding information is passed on to other members of the Research Office in a timely and efficient manner.



Assist the Research Development Manager and Research Development Associate in organising and implementing research development initiatives in the Trust and promoting the Trust’s research activities to internal and external stakeholders.



Contribute to the collection of data and preparation of reports including assessment of grant submissions, grant awards, research publication outputs and other assessments of research activity, outputs and impact.



Promote the corporate image of the Trust and its research activity.



Provide costs for research grants, liaising with Finance and other Trust departments as necessary.



Act as Associate AcoRD (Attributing the costs of health and social care Research & Development) Specialist, maintaining a working knowledge of AcoRD and its application in the NHS.



Source relevant funding opportunities for researchers in the Heart, Lung and Critical Care Clinical Group.



Support the research development team with grant administration.


This advert closes on Monday 30 Sep 2024

The post holder will support the reproductive health and childbirth research portfolio at Guy's and St Thomas' NHS Foundation Trust.

Please see the attached Job Description for an Detailed job description and main responsibilities. If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)

Acting as a patient / participant advocate at all times, the post holder will provide clinical research and administrative assistance to a number of research studies taking place within the department. The post holder will be expected to support the identification of participants into studies in the field of Reproductive Health and Childbirth, and ensure that research records are accurate and up to date. The post holder will be required to verbally explain and outline research projects and gain permissions for research participation. The post holder will also undertake venepuncture and work within the department laboratories. The post holder will also provide essential administrative support to the Women’s Health team and ensure that research records and site files are accurate and up to date. The post holder will ensure the well-being of participants by adhering to research protocols and will contribute to the development and ongoing maintenance of Standard Operating Procedures (SOPs).

If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)

South London Comprehensive Local Research Network

The NIHR Comprehensive Clinical Research Network (CCRN) was established by the Department of Health to improve the speed, quality, and integration of clinical research, resulting in improved patient care. It is managed by the NIHR Clinical Research Network Coordinating Centre. The NIHR CCRN comprises 25 local research networks (CLRNs) in England, each including primary care, secondary care, tertiary care and mental health NHS service providers.

Department of Women & Children’s Health

The KCL Department of Women and Children’s Health forms the research arm of the Women’s Health Academic Centre, King’s Health Partners, to develop synchrony and excellence between clinical service, research and teaching. King’s Health Partners Academic Health Sciences Centre (AHSC) is a pioneering collaboration between one of the world’s leading research-led universities and three of London’s most successful NHS Foundation Trusts. Our AHSC is one of only five in the UK. It consists of King’s College London, and Guy’s and St Thomas’, King’s College Hospital and South London and Maudsley NHS Foundation Trusts.

Please see the attached Job Description for an Detailed job description and main responsibilities. If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)


This advert closes on Monday 16 Sep 2024

The Department of Twins Research team is seeking a highly motivated person to join their group as a Assistant Clinical Research Practitioner with experience and knowledge of working in an NHS/University research environment, along with experience of working with participants involved in multiple, large, complex studies.


Post holder will be expected to describe the studies and obtain fully informed consent from participants ensuring that any research undertaken within the department, safeguards the wellbeing of the participants and is conducted according to Good Clinical Practice (GCP). They will be expected to carry out a range of clinical assessments in line with accepted standards of practice and be competent in some clinical skills including venepuncture and cannulation.


Post holder will be required to interact & engage with participants throughout the study period, answer any questions and liaise with
multidisciplinary teams, therefore must have a professional approach to work and will be expected show initiative and work well as part of a team.
Excellent communication skills are essential and the role requires the ability to work both independently and with others to inspire trust &
confidence.


Much of the role will be conducted via clinics within GSTT, however flexibility with time and adaptability to different environments will be necessary to meet study requirements.


We reserve the right to close the vacancy early dependent on interest

Please see attached Job Description and Person Specification for more information on the role and its requirements.

TwinsUK is the UK’s largest adult twin registry and the most clinically detailed in the world.Professor Tim Spector from King’s College London set up the cohort in 1992 to investigate the incidence of osteoporosis and other rheumatologic diseases in several hundred monozygotic (identical) twins. We now have over 15,000 identical and non-identical twins from across the UK, with ages between eighteen and one hundred and our research has expanded to include multiple diseases and conditions.

There are excellent opportunities for professional and personal development as part of this role, with access to some CPD funding. We provide a comprehensive induction programme and ensure that all staff have tailored, individual personal development plans with support for further training. Opportunities for developing new research and clinical skills are available and actively encouraged.

The usual working hours for the post are Monday to Friday 9am-5pm, although the post holder may need to be flexible to accommodate participants visits and assessments outside of these hours occasionally.

TwinsUK aims to investigate the genetic and environmental basis of a range of complex diseases and conditions. Current research includes the genetics of metabolic syndrome, cardiovascular disease, the musculoskeletal system, ageing, sight as well as how the microbiome affects human health. The TwinsUK cohort is now probably the most genotyped and phenotyped in the world.

Please see attached Job Description and Person Specification for more information on the role and its requirements.


This advert closes on Tuesday 13 Aug 2024

A fantastic opportunity has arisen to join the Guy's & St Thomas' NHS Foundation Trust Finance Team as Finance Manager (Research & Development) supporting the Trust’s Research & Development function.

Guy’s and St Thomas’ is one of the top performing Trusts in the UK for undertaking pioneering clinical research. In addition to being one of the highest recruiters of participants into clinical trials and studies in England, we have an ambitious and innovative operational research agenda.

As a CCAB qualified accountant, you will have significant post qualification experience and proven finance business partnering experience. Previous experience of NHS R&D finance is desirable, although not essential. Your key attributes will include communication, leadership, planning, costing and analytical skills.

This is a key role within the R&D team and will provide leadership both the annual business planning process and monthly financial reporting. Additionally, the role will lead on the financial aspects of external R&D reporting.

The individual appointed will lead a team four providing financial support covering all aspects of R&D finance.



Act as an expert in the highly specialised area of R&D Finance.

Ensure senior managers within the R&D Directorate and other finance staff within the trust adhere to the rules regarding R&D funding.

Shape the development and direction of the R&D finance team.

Be responsible for preparing the monthly finance reports and forecasts for the directorate, and presenting these within the directorate and to more senior staff.

Lead on the accurate provision of costings for research grant applications.

Guy's and St Thomas' is among the UK's busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.

We have a reputation for clinical excellence and high-quality teaching and research. We are part of King's Health Partners, one of eight accredited UK academic health sciences centres. In partnership with King's College London we have dedicated clinical research facilities and a National Institute for Health Research (NIHR) Biomedical Research Centre.

Patients are at the heart of everything we do and we pride ourselves on ensuring the best possible patient experience as well as safe, high quality care. We are proud to have one of the lowest mortality rates in the NHS. Following a comprehensive Care Quality Commission (CQC) inspection in 2019 we maintained our overall rating of 'good'. Our adult community services achieved a rating of 'outstanding'.

The commitment of our 24,000 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2019 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

Please refer to the attached Job Description and Person Specification for a full list of role requirements and main responsibilities.


This advert closes on Monday 12 Aug 2024

Job overview

Are you an experienced and dynamic clinical research nurse who can confidently lead our research team and manage our growing portfolio of Oncology and Haemophilia Clinical Research? Then this role might be for you!

Applicants must be a registered adult nurse with evidence of continuing professional development. You should have good experience in working within the NHS, a strong clinical background and a desire and willingness to learn & develop others. Candidates must demonstrate excellent communication and interpersonal skills, and have the ability and initiative to work independently and manage a patient caseload across a variety of research studies.

We have two vacant position:

Rotational Research Nurse - this post will rotate across our Oncology and Haematology Research Team . The post holder will have opportunity to learn about different tumour groups, gain knowledge in different systemic anti-cancer therapy and research patient pathway.

Haemophilia Research Nurse

You will be looking after patient with Haemophilia and involved in managing exciting new trials especially gene therapy.
• Work within EU clinical trial directives in accordance with ICH GCP (International Conference on Harmonisation and Good Clinical Practice) ensuring that the clinical trial protocol is adhered to at all times.
• Identify patients suitable for entry into clinical trials by attending clinics (screening notes/consultant referral) and Multidisciplinary Team (MDT) meetings.
• Participate in the informed consent process acting as a resource and support to patients and their families
• Co-ordinate the research patient pathway from screening through to trial closure
• Ensures that adequate precautions are taken to minimise the risk of cross-infection in relation to the safe disposal of body fluids including blood products.
• Advise the local nursing team who administer trial drugs, be aware of and report any side effects as outlined in the protocol.
• Maintain adequate patients’ records and ensure all relevant information is documented in the patient’s medical and nursing notes.
• Responsible for accurate completion of Clinical Report Forms (CRFs).
• Responsible for the collection, co-ordination and computerisation of data generated from the clinical trials.
• Keep up to date with current practices for cannulation, phlebotomy, care of patients with Central Venous Access lines and handling and administration for cytotoxic chemotherapy.
• Act as a role model for excellence in oncology based research.

Working for your organisation

As part of Kings Health Partners, the Oncology and Haematology Clinical Trials (OHCT) team is made up of ninety plus staff members consisting of Research Nurses, Clinical Trial Practitioners, Clinical Trial Coordinators and the Safety & Support Team at Guys’ and St Thomas’ NHS Foundation Trust.

We work closely with the oncology and haematology medical teams to recruit patients to our trials and to ensure patients are monitored closely throughout. We have a large portfolio of Phase II and III trials; which are split into teams for specific tumour groups. We also have a team dedicated to early phase trials and run weekly early phase clinics in the Clinical Research Facility. We attract commercial and non-commercial trials, ranging from interventional drug or radiotherapy trials to observational studies.

Our mission statement is ‘Improving treatment choice, clinical care and outcomes for cancer patients through innovation, dedication and excellence in clinical trials’.

Detailed job description and person specification can be found in the attached documents accompanying this advert.


This advert closes on Sunday 28 Jul 2024

We have an exciting opportunity that have arisen at Guy's and St Thomas' NHS Foundation Trust.



We are looking for two enthusiastic Research Nurses to play a key role in developing a comprehensive Cardiovascular Biobank that leverages the high volume of clinical activity with King’s Health Partners (KHP).



The successful candidates will become an integral part of our KHP biobank team and will beresponsible for the assessment, planning, organisation, recruitment of research participants and collection of patient samples.



The successful individuals will be dynamic, have excellent communication and interpersonal skills, as well as an ability to work independently and flexibly. They will be strong advocates for patients and for research, able to effectively recruit participants and provide the needed support to these individuals.

The post will involve identifying patients treated at our NHS Trust hospital sites, namely, at Guy’s and St Thomas’, King’s College, Royal Brompton and Harefield Hospitals.

Typical duties will involve consenting patients prior to their hospital visit, arranging for collection of samples, collating patient related clinical data and follow up of patients.

The role will involve working closely with multidisciplinary clinical teams and liaising regularly with a dedicated Data manager to ensure comprehensive recording of sample associated data and patient follow up.

These post’s will be based atbased at GSTT/KCH and may extern to Royal Brompton Hospital and Harefield Hospital subsequently.It is a requirement of employment that the post holder be prepared to work at any additional or different location owned or served by the Trust, either on an on-going or temporary basis, according to the demands of the service and,on occasion, working outside of normal working hours. Should the need arise, this will be agreed well in advance.

The post holder will work within a team of biobank researchers and research nurses. Key relationships include Modern Matron for Research, Consultants and Junior Medical Staff, Nursing Staff, Clinical Nurse Specialists, Allied Health Professionals, Administrative and Clerical Support Staff, Professional and Technical staff. Staff within non-commercial bodies and pharmaceutical companies.

Please see the Job Description and Person Specification for detailed information regarding the responsibilities and requirements for this post.




This advert closes on Sunday 14 Jul 2024

The post holder will support the reproductive health and childbirth research portfolio at Guy's and St Thomas' NHS Foundation Trust.

Please see the attached Job Description for an Detailed job description and main responsibilities. If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)

Acting as a patient / participant advocate at all times, the post holder will provide clinical research and administrative assistance to a number of research studies taking place within the department. The post holder will be expected to support the identification of participants into studies in the field of Reproductive Health and Childbirth, and ensure that research records are accurate and up to date. The post holder will be required to verbally explain and outline research projects and gain permissions for research participation. The post holder will also undertake venepuncture and work within the department laboratories. The post holder will also provide essential administrative support to the Women’s Health team and ensure that research records and site files are accurate and up to date. The post holder will ensure the well-being of participants by adhering to research protocols and will contribute to the development and ongoing maintenance of Standard Operating Procedures (SOPs).

If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)

South London Comprehensive Local Research Network

The NIHR Comprehensive Clinical Research Network (CCRN) was established by the Department of Health to improve the speed, quality, and integration of clinical research, resulting in improved patient care. It is managed by the NIHR Clinical Research Network Coordinating Centre. The NIHR CCRN comprises 25 local research networks (CLRNs) in England, each including primary care, secondary care, tertiary care and mental health NHS service providers.

Department of Women & Children’s Health

The KCL Department of Women and Children’s Health forms the research arm of the Women’s Health Academic Centre, King’s Health Partners, to develop synchrony and excellence between clinical service, research and teaching. King’s Health Partners Academic Health Sciences Centre (AHSC) is a pioneering collaboration between one of the world’s leading research-led universities and three of London’s most successful NHS Foundation Trusts. Our AHSC is one of only five in the UK. It consists of King’s College London, and Guy’s and St Thomas’, King’s College Hospital and South London and Maudsley NHS Foundation Trusts.

Please see the attached Job Description for an Detailed job description and main responsibilities. If you require further information please contact Glen Nishku (glen.nishku@gstt.nhs.uk)


This advert closes on Sunday 30 Jun 2024