Senior Laboratory Research ScientistShort summary Do you have a keen interest in biological mass spectrometry and applying state-.....
Senior Laboratory Research Scientist
Short summary
Do you have a keen interest in biological mass spectrometry and applying state-of-the-art proteomic technologies?
We have an opportunity for a talented, experienced, and motivated Senior Laboratory Research Scientist in the Proteomics Scientific Technology Platform at the Francis Crick Institute. The post holder will help us provide a world class platform to contribute towards key research in collaboration with the wider Crick scientific community. This is a lab-based position, responsible for driving forward qualitative and quantitative proteomic and clinical proteomic projects, from experimental design through sample preparation to data analysis.
The Proteomics STP houses a broad range of mass spectrometers including a Thermo Scientific Orbitrap Eclipse Tribrid with FAIMS and ETD, Exploris 480, Q Exactive UHMR, Bruker timsTOF Ultra and Pro2, Waters Select Cyclic and SYNAPT G2Si HDMS. The role will involve setting up new experiments as collaborative projects arise using the available mass spectrometry technologies to both qualitatively and quantitatively measure proteins.
Key Responsibilities
These include but are not limited to:
• Planning of experiments, decision making about which pipeline to take, and independently executing experiments for projects.
• Performing both standard and bespoke proteomics experiments starting with sample preparation from a variety of biological sources using common biochemical methodologies for cell lysis, SDS-PAGE, in-gel, in-solution, TCA and acetone precipitation digest protocols, TMT labelling, high pH chromatographic fractionation and label free quantification.
• LC-MS/MS nanoUHPLC data acquisition, evaluation, and processing of raw data.
• Communication of results in collaboration.
Other typical activities may include:
• Collaborating with other lab members on/Assisting other lab members with/ research projects.
• Providing experimental or technical support to other lab members.
• Providing technical expertise/ input for the development, refinement and troubleshooting of novel methodologies.
• Participating in academic activities, including group meetings and journal clubs, seminars
Find out what benefits the Crick has to offer:
For more information on our great pay and benefits package please click here: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/pay-and-benefits
Equality, Diversity & Inclusion:
We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.
Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.
The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.
Read more on our website: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/equality-diversity-and-inclusion