Total 10 Junior Executive level Science / R&D / Research job vacancies in Oxford, OX14

To help organise and facilitate co-design workshops with community groups and individuals with lived experience of psychosis from Bangladeshi, Black African, and Black Caribbean backgrounds. Screening and recruitment of patients diagnosed with psychosis and patients at ultra high risk pf psychosis. This will involve speaking to referrers regularly, attending clinical team meetings, visiting community mental health teams, hospital wards, as well as home based treatment teams. There will be monthly recruitment targets for all studies. The post-holder will be joining a team of research assistants to help meet these targets. Completing eligibility screening assessments and seeking informed consent from patients. Carrying out the assessments for the trials. The trial patients will be assessed on a range of measures at a number of time points for each study. You will need to arrange these interviews and administer clinical interviews, assessment tasks, and self-report questionnaires. Participants will be seen in clinic settings or at home across a large geographical area. Patients are seen in multiple NHS trusts including: Oxford Health, Northamptonshire Healthcare, Berkshire Healthcare, and Central Northwest London (Milton Keynes). Assessments will be carried out blind (i.e. you should not know which condition thepatients have been randomised to). You will need to remind staff and patients not to tell you the allocation. And you will need to report if you have become unblinded. It will be crucial to maintain very high follow-up rates for the trial participants, meaning you will need excellent engagement skills. Good record-keeping will be needed, including updating medical records with trial progress and managing recruitment databases. Follow standard operational procedures for the trial and NHS Trust policy regarding safeguarding of vulnerable adults and children. Produce regular reports on the recruitment process and assessment Please refer to the job description attached for a comprehensive list of duties

Responsible for the management and Coordination of the Hydroxychloroquine (HCQ) research study across the Thames Valley and UK wide Co-ordinate recruitment of participants while incorporating collection of confidential patient information and samples to be dispatched to the genetic laboratory Liaise with the Chief Investigator (C.I) and assigned Research Nurse Ensure all paper and electronic study documentation, including regulatory and approval documents, contracts and finance, staff certification, training and case report forms, are filed in the trial master files (TMF) The TMF being kept up to date at all times for monitoring and audit purposes. Work at all times in accordance with The International Conference on Harmonisation Good Clinical Practice Guidelines (ICH-GCP).

This post is central to the successful delivery of major new research trials. Screening and recruitment of patients diagnosed with psychosis and patients at ultra high risk pf psychosis. This will involve speaking to referrers regularly, attending clinical team meetings, visiting community mental health teams, hospital wards, as well as home based treatment teams. There will be monthly recruitment targets for all studies. The post-holder will be joining a team of research assistants to help meet these targets. Completing eligibility screening assessments and seeking informed consent from patients. Carrying out the assessments for the trials. The trial patients will be assessed on a range of measures at a number pf time points for each study. You will need to arrange these interviews and administer clinical interviews, assessment tasks, and self-report questionnaires. Participants will be seen in clinic settings or at home across a large geographical area. Patients are seen in multiple NHS trusts including: Oxford Health, Northamptonshire Healthcare, Berkshire Healthcare, and Central Northwest London (Milton Keynes). Although some assessments may take place remotely, it is likely there will be extensive travel which would be facilitated by having valid driving licence, and access to own or other independent means of transport. Assessments will be carried out blind (i.e. you should not know which condition the patients have been randomised to). You will need to remind staff and patients not to tell you the allocation. And you will need to report if you have become unblinded. It will be crucial to maintain very high follow-up rates for the trial participants, meaning you will need excellent engagement skills. Good record-keeping will be needed, including updating medical records with trial progress and managing recruitment databases. You will need to follow standard operational procedures for the trial and NHS Trust policy regarding safeguarding of vulnerable adults and children. You will need to produce regular reports on the recruitment process and assessments. Brief clinical reports will need to be written based on the trial assessments. Any adverse events will need to be reported to the team. You need to regularly enter and check data in the electronic databases. Attendance at supervision will be expected, and at appropriate research team meetings. There are a number of experimental and clinical trials being run in the research team. The postholder will be expected to contribute as appropriate. There will also be opportunities to assist clinical psychologists in elements of clinical work. Administrative duties related to the project. Other duties appropriate to the grade as directed by the grant-holders. Work within the guidelines set out by the Data Protection Act, the Code of Ethics, and with full understanding of confidentiality issues. Contribute towards consistent and safe practices by being aware of and adhering to all the relevant Trust policies and procedures. Please see the job description and person specification attached to this advert for more information on the job role.

Collect and maintain data and study documentation (including site files), where appropriate in a systematic manner and ensure accurate data entry in accordance with the legislation and guidelines governing research in the UK, ensuring the confidential storage of data at all times Provide written reports regarding the progress of the research to the research team.

We are seeking to appoint a Research Assistant with computational skills and the biological understanding of cancer-causing pathogens to work on computational analysis at the Ludwig Institute for Cancer Research, University of Oxford

In this role your duties will include provide statistical analysis plans for studies and handle day-to-day planning to keep the work on track and efficient and the performance of integrative analysis of single-cell RNA and ATAC seq data. To support the research endeavours effectively, you will develop or customize analytical tools and resources in collaboration with other team members and attend to scientific seminars, meetings and training as appropriate.

It is essential that you hold a degree in a life science or computational subject, together with demonstrable experience and ability in biostatistics or bioinformatics. You will also have previous experience in a laboratory research setting, and use of techniques including but not limited to PCR, qPCR, gel electrophoresis, western blots, and cell culture. The ability to organise and prioritise work efficiently whilst delivering results to the required standard and to an agreed schedule is also essential in this role.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 12 months and is funded by the Ludwig.

Only applications received before 12 midday on Monday 12 August 2024 will be considered. Please quote 172112 on all correspondence.

Full-time, Fixed term until 03 July 2027

Applications are invited for a Research Assistant neuronal cell biologist to work on a project to target calcium channels in Parkinson’s disease. The project, funded by the Michael J Fox Foundation and in collaboration with Lario Therapeutics, represents an exciting opportunity to undertake translation work at the interface between academic research and pharmaceutical target and drug discovery in an exceptional setting. This work will develop new inhibitors of calcium channels as a neuroprotective strategy to protect vulnerable dopamine neurons in Parkinson’s working with induced pluripotent stem cell (iPSC)-derived dopamine neurons generated from Parkinson’s patients.

Duties will include undertaking laboratory experiments; biochemistry, immunocytochemistry, cell and molecular biology; growth and differentiation of iPSC lines; interpretation of data; imaging analysis; and preparation of data for publication. You will have excellent practical experience of working with neuronal cell cultures and good knowledge of cellular models of neurodegenerative disease. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is essential.

Applicants must hold, or be near completion of, a BSc/MSc in a relevant area of research and have experience in cellular neuroscience or molecular cell biology relevant to analysis of neuronal phenotypes.

The post is available immediately and runs until 03 July 2027. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, South Parks Road, Oxford, OX1 3QU

Informal enquiries may be directed Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk).

Closing date for applications is midday on Monday 12th August 2024. Interviews are likely to be held in the week commencing 26th August 2024.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

We, as a Department and Community, will be considerate and welcoming of all people, regardless of age, disability, gender reassignment, marriage and civil partnership, pregnancy and maternity, race, religion or belief, sex, sexual orientation, gender identity, and socio-economic background. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion

Full-time, Fixed-term until 30th April 2027

Applications are invited for a Research Assistant to work on a highly collaborative and interdisciplinary project to develop transgenic rodent models of Parkinson’s disease. The work will support projects seeking to use rodent models of disease to understand the earliest stage of neurodegeneration at a point in which neuronal dysfunction precedes neuronal loss, offering an early therapeutic window for therapy. The post will be based in the Laboratory of Molecular Neurodegeneration in the Department of Physiology, Anatomy and Genetics, and is supported by the Wellcome Trust and an international consortium funded by an Aligning Science Across Parkinson’s (ASAP) grant.

Duties include colony management, breeding and maintenance of lines of transgenic rodents; collection of brain tissue for gene expression analysis; general laboratory management, preparation of data for publication; contributions to wider project planning and determine the most appropriate methodologies to test hypotheses. You will have a good working knowledge of molecular and cellular biology, excellent practical experience of working with animal models and an interest in pre-clinical in vivo models of neurological disease. Previous experience of the management and maintenance of transgenic rodent lines would be an advantage. The ability to innovate, trouble-shoot technical problems, be meticulous in practical work and in record keeping is also essential.

Applicants must hold a BSc/MSc in a relevant area of research and will have excellent practical experience of working with animal models.

The fixed-term post is available immediately and until 30th April 2027. The post will be based in the Laboratory of Molecular Neurodegeneration, Kavli Institute for Nanoscience Discovery, New Biochemistry, Phase 2, Parks Road, Oxford. Informal enquiries may be directed to Professor Richard Wade-Martins (richard.wade-martins@dpag.ox.ac.uk). Closing date for applications is midday on Wednesday 31st July 2024. Interviews are likely to be held in the week commencing 12th July 2024.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion.

We have an exciting opportunity to recruit a Research Assistant in Vaccine Development to support the fantastic work of the Bioprocess and Analytical Development group here at the Jenner Institute, Nuffield Department of Medicine.

This role provides an opportunity to work with a team of scientists developing vaccines (adenovirus vectored, recombinant protein, VLP-based, etc) and advancing knowledge on a range of infections, including rabies, COVID-19 and Epstein-Barr virus (EBV).

As Research Assistant, you will develop your skills in experimental design, planning and analysis, while making a meaningful contribution to global health through developing new vaccines. You will be responsible for producing high quality data using a range of modern laboratory techniques, such as cell culture (mammalian and microbial), chromatographic protein purification, ELISA, digital PCR, DNA cloning, flow cytometry and viral culture. You will also be responsible for developing, following, and adapting experimental protocols for a range of experimental techniques, such as DNA cloning, mammalian and microbial cell culture, qPCR, ELISA, flow cytometry, viral culture, chromatographic protein purification and filtration processes (TFF, depth filtration, etc).

To be successful in this role, you will hold a BSc degree in medical science or a related discipline along with practical experience of biology, medical science or similar laboratory work. You will have knowledge of vaccinology, infectious disease, and/or molecular biology and the ability to work within established research programmes, with the potential to contribute ideas for new and improved experiments. You will have excellent communication skills, including the ability to maintain clear laboratory records, write for publication, and represent the group at meetings and conferences as well as good interpersonal skills and ability to work effectively with others.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and
experience.

This position is offered full time on a fixed term contract for 2 years and is funded by the Department and SpyBiotech.

Only applications received before 12 midday on Thursday 18 July 2024 will be considered. Please quote 173115 on all correspondence.

An opportunity for a full-time Finance Assistant has arisen in the Department, reporting to the Computer Science Senior Finance Officer - GL. This post is primarily financial administration, ensuring financial transactions are recorded and processed accurately in line with financial controls.

We are seeking applicants with experience of working in a financial environment who have a good level of numerical accuracy, who are committed to achieving both individual and team goals through excellent team working and communication skills. Applicants should have the ability to work methodically, generating high volumes of accurate work with meticulous attention to detail. You will be educated to GCSE standard or equivalent, and be a competent user of Microsoft Excel. Previous experience of working in an accounting environment, within a higher education or research establishment and experience of the University’s Oracle financial system is desirable.

Applications for this vacancy are to be made online. You will be required to upload a supporting statement as part of your online application. The supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

The post is a full time permanent contract.

The closing date for applications is 12 noon on 22nd April 2024. Interviews are expected to be held in late April or early May.

We are a Stonewall Top 100 Employer, Living Wage, holding an Athena Swan Bronze Award, HR excellence in Research and Race Equality Charter Bronze Award.

Our staff and students come from all over the world and we proudly promote a friendly and inclusive culture. Diversity is positively encouraged, through diversity groups and champions, for example http://www.cs.ox.ac.uk/aboutus/women-cs-oxford/index.html , as well as a number of family-friendly policies, such as the right to apply for flexible working and support for staff returning from periods of extended absence, for example shared parental leave.

Demonstrating a commitment to provide equality of opportunity. We would particularly welcome applications from women and black and minority ethnic applicants who are currently under-represented within the Computer Science Department. All applicants will be judged on merit, according to the selection criteria.

Full-time, Fixed-term until 18 April 2025

The Cragg Group at the University of Oxford are seeking a Research Assistant to join a project funded by the MRC to explore the role of astrocytes in the regulation of dopamine function in health and parkinsonism.

The successful candidate will become a member of the Cragg group and will assist with studies to elucidate dopamine transmission, its regulation by astrocytes and related signaling molecules in mouse brain, in models of Parkinson’s disease. The candidate will have the opportunity to collaborate on projects with the Cragg Group’s internal and external partners and when appropriate, give advice and guidance to other members of the Group. The candidate will have responsibility for conducting, analyzing and interpreting scientific data generated from experiments, ensuring that the data are of the highest quality.

In addition to having, or nearing completion of, a first degree in a relevant science, candidates should have laboratory experience and some knowledge of the field of neuroscience. The candidate should also be able to manage their own research and administrative activities. The candidate needs experience of following and adapting protocols and selecting appropriate experimental methodologies. Experience of working with mice is desirable.

The post holder will work in the Group led by Professor Stephanie Cragg, and will be based at the Department of Physiology, Anatomy and Genetics, Sherrington Building, Parks Road, Oxford, OX1 3PT.

Closing date for applications is midday on Monday 15th January.

Interviews are likely to be held on the week beginning 29nd January.

Applications are particularly welcome from women, black and minority ethnic candidates who are under-represented in academic posts in Oxford.

While this is a full-time role, we welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

We, as a Department and Community, will be considerate and welcoming of all people, regardless of race, ethnicity, religion, disability, sexual orientation and gender identity. We acknowledge societal inequalities and how these impact us, and those around us, personally and professionally. – DPAG Statement of Inclusion