ROLE SUMMARY:  

Although rare, Multiple Myeloma is the second most common hematologic malignancy worldwide, with a 5 year survival rate of 54% and high rate of relapse on therapies currently considered Standard of Care. The current Multiple Myeloma marketplace has an estimated value of ~ $32B in most major markets by ‘2024. B-cell maturation antigen (BCMA) is a novel target that is highly active in MM, with multiple recently approved medications across different modalities. This role provides a unique opportunity to join Pfizer’s Elrexfio team as we bring this breakthrough to patients. 

Elrexfio (elranatamab) is approved across 6 global markets including in the US and EU, for Relapsed/Refractory Multiple Myeloma in the Triple Class Exposed setting. Additional approvals and launches in this indication are expected throughout 2024, and there are 4 Phase 3 trials of Elrexfio currently enrolling, which investigate use earlier in MM treatment.

The Global Marketing Director, Elrexfio will report to the Global Marketing Lead, Elrexfio, and will be responsible for leading HCP marketing and brand strategy to maximize the brand opportunity across the lifecycle. Key areas of responsibility will include driving HCP strategies and execution to differentiate Elrexfio currently and in future indications within an increasingly crowded and dynamic MM market, optimizing the omnichannel mix, overseeing CI and competitive insights, and supporting regional and local pull through.   

ROLE RESPONSIBILITIES:  

With minimal supervision responsibilities will include but are not limited to: 

Lead and manage the brand value proposition 

• In partnership with Business Insights and ensuring a diversity of sources, conduct market research to inform Patient Journey, Competitive Landscape and Positioning, with particular attention to future indications 

• Work closely with the Global Governance Team to own and evolve the core brand strategy and positioning for future indications 

• Optimize overall differentiation message relative to SoC and competition for HCPs and align to value proposition for other stakeholders, including market access, patients, regulators and policy

• Lead scenario planning in earlier lines and evolve brand positioning to pull through differentiation in future indications

Content/Brand development (cross-stakeholder) 

• Responsible for executing Core Content package for HCPs

• Liaise with key global cross functional stakeholders involved in the development and approval of the content including but not limited to legal, regulatory, and medical colleagues 

• Develop global guidance to optimize omnichannel execution in market and strategically allocate resources to maximize the value of globally-developed materials and channels (e.g., congress, training, speaker training) 

Ensure continued value proposition of Multiple Myeloma Franchise  

• Partner with Pfizer Competitive Intelligence team and cross-functional CI team to monitor competitive landscape across current and future indications, continuously driving alignment on implications, while projecting and tracking key catalysts, including competitive timelines 

• Lead team in leveraging CI to inform brand strategy, optimize differentiation, and develop competitive scenarios 

• Build and refine target product profiles to align with key stakeholder needs and incorporate clinical, regulatory, medical, and market access considerations 

• Integrate latest data and evidence into promotion working with the markets to optimize approach to messaging on maturing pivotal endpoints, real-world evidence, key sub-analyses, and quality of life 

• Drive HCP advisory boards/panels, and KOL stakeholder engagements through coordination with the Hematology KOL Strategy Lead 

Team leadership  

• Based on HCP stakeholder needs, ensure alignment of Elrexfio commercial strategy with clinical program, regulatory strategy and label, and real-world data plan to support key claims 

• Mentor and indirectly manage 2 global senior managers and 1 manager supporting HCP tactical execution 

• Support the annual operating plan process, long range forecasting, and oversee tactical plan development and budgeting 

• Manage key agency and vendor relationships to drive effective execution 

• Conduct all activities and make all decisions in accordance with Company policies & SOPs, Pfizer Values & global regulatory guidelines 

QUALIFICATIONS:  

We are seeking an experienced, world-class marketer with experience launching or growing brands in highly competitive environments. An ideal candidate will be fast learning and highly motivated, proactive and take personal accountability for work quality. The candidate must work well in a self-directed team environment, with minimal instruction needed, assume increasing levels of responsibility, take accountability for decisions and outcomes, and lead/mentor others.  

• BA/BS - degree required. Advanced degree preferred 

• Oncology experience, particularly in hematology or Multiple Myeloma, desirable 

• Minimum 10 years of business experience, fewer with advanced degree, including pharmaceutical industry or consulting experience in marketing, strategy or new product launch 

• Demonstrated experience in HCP marketing strategy and execution, including developing marketing campaigns and messaging 

• Proven ability to manage day to day planning and operational activities including strong project, time management and organizational skills 

• Demonstrated ability to identify priorities and exercise sound judgment in accomplishing work in appropriate priority order to ensure deadlines are met and leaders are prepared 

• Must demonstrate Courage, Excellence to work alongside a matrixed team for a breakthrough medicine in a mature multiple myeloma market 

• Exceptional communication skills, ability to infuse enthusiasm, energy, confidence into teams and drive change 

• Ability to move fast in response to what is happening in the external marketplace 

• Mature, self-driven colleague, with exceptional learning agility and a high degree of comfort with ambiguity. Ability to make and execute decisions independently. 

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Potential for international travel up to 25%.

Work Location Assignment: NYC Headquarter or Collegeville, PA

• Last date to apply for Job: March 27, 2024.

Relocation assistance may be available based on business needs and/or eligibility.

ROLE SUMMARY

• The clinician medical monitor may contribute towards providing medical and scientific expertise and oversight for Clinical Trials.

• The clinician medical monitor may be required to design a development strategy for multiple protocols designed to obtain worldwide approval for a compound or group of compounds.

ROLE RESPONSIBILITIES

Accountable for safety across the study:

• Provide study team with medical advice for all medical issues during risk assessment and mitigation planning to enable quality, compliance and patient safety at the trial, site and patient level.
• Ensures development of and adherence to the Safety Surveillance Review Plan (SSRP). Consistent with the SSRP, performs and documents regular review of individual subject safety data, and performs review of cumulative safety data with the safety risk lead. As appropriate, the clinician medical monitor may delegate these responsibilities to the study clinician scientist identified in the SSRP. The specific components of safety data review are detailed in the appropriate SOPs and the “Safety Data Review Guide – for Clinicians.”
• Monitor study safety issues and provide input to serious adverse events (SAEs) reports. Provides appropriate medical context in terms of risk factors, medical history and other important medical factors required to put the SAE or AE into appropriate medical context.
• Participates in the Safety Review Team to evaluate medical benefits/risks to support targeted clinical indications.
• Reviews literature as needed to respond to safety questions or those posed by the Safety Review Team, Data Monitoring Committee (DMC) or other individuals or bodies involved with the study.
• Communicates safety information to sites across the study and provides responses to questions on safety.

Protocol design and strategy:

• Contributes towards the medical input during protocol development and updates to the clinical development plan.
• Work closely with other medical monitors to ensure that documents (protocol, Informed Consent Document [ICD], etc.) meet regulatory requirements and company policy and has been reviewed by IRB/IECs.
• Provides medical input into country feasibility.

Support study team

• With supervision of medical monitor (director/Sr director) provides clinical input to protocol/study team for monitoring guidelines, statistics analysis plans, ICDs, clinical review forms, data edit checks, data quality planning, as needed
• Contributes to contract research organization / vendor selection to ensure study is conducted consistent with protocol requirements, clinical plan expectations, and study timelines; this includes ensuring medical/technical requirements for data integrity are applied.
• Works with study team to ensure high quality of data e.g. appropriate patient population, adequacy of clinical assessments as study is ongoing.
• Contributes to medical review and interpretation of efficacy and safety data from clinical trials; this includes delivery of top-line report in collaboration with study statistician, and delivery of clinical study report in collaboration with medical writer and accountable for overall quality and timeliness of analysis and reporting.
• Provides protocol specific training to study team, investigators, clinical research associate, and others.
• Interacts with healthcare professionals at sites during the conduct of the study to enable quality, compliance and patient safety at the trial, site and patient level.
• Interacts with DMCs and steering committees as required.
• Notifies appropriate study team personnel of the need to inform investigators of any changes in research activity and any significant new adverse events.
• Monitor investigator compliance with protocol and regulatory requirements.
• Support study team in issues resolution, study closeout, audit responses, inspection readiness, etc.

• Supports the program team:
• Under supervision (director/Sr director) authors clinical sections of regulatory documents (Investigator Brochure, Annual Reports, Investigational New Drug sections, clinical study report).
• May co-author abstracts, posters, presentations and publications.
• May contribute budget execution of protocols.

Interact with regulatory authorities, key opinion leaders, and principal investigators:

• May support Clinical Regulatory Authority interactions accountable for providing responses.
• Liaise with Key Opinion Leaders and Principal Investigators in countries to build a Key Opinion Leaders /Principal Investigators network for new trials.

BASIC QUALIFICATIONS

• Licensed by a health authority to prescribe medicines (independent of supervision) for at least one year (post "intern/houseman" year) and has utilized the license to prescribe medicines in a patient care setting for an aggregate duration of at least one year.
• Possesses the ability to critically evaluate medical/scientific information.
• Excellent written an oral communication.
• Understands the design, development, and execution of clinical programs and studies.
• Capacity to adapt to a fast pace and changing environment

PREFERRED QUALIFICATIONS

• Medical degree (M.D./D.O. or equivalent).
• Documented work experience/knowledge of statistics
• Training and experience in infectious diseases and/or infection control in the hospital setting is preferred.
• Experience with investigational clinical trials is preferred.
• No pharmaceutical industry experience required

 
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Work Location Assignment: On Premise Relocation eligible

Relocation assistance may be available based on business needs and/or eligibility.

Why Patients Need You

Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is innovative and customer oriented. Whether you are involved in manufacturing, testing, or compliance, your contribution will directly impact patients.

What You Will Achieve

The PGS Learning Technology & Solutions (LT&S) Lead is responsible for leading a team of individual contributors who provide global expertise to the PGS network focused on Learning Management System (LMS) and related technology. The LT&S Team Lead serves as the overall PGS business owner / representative for the Pfizer LMS, partnering with key stakeholders to ensure the effective implementation and optimization of the global PGS LMS. The LT&S Lead represents PGS on the Enterprise Technology Steering Committee and sponsors the PGS global LMS forum (CoP) to drive excellence and compliance, including effective adoption of best practices.

The LT&S Team is an integral part of the PGS Personnel and Training Management Process Center of Excellence (COE) and partners with sites and functions to establish, manage and execute a digital learning roadmap for PGS. In addition, the LT&S team ensures global training programs/solutions are developed to support colleague readiness and that appropriate learning methods and technologies are used for delivery. To enable the Learning Vision, the LT&S team conducts external benchmarking, evaluates business trends, and works with Pfizer digital partners to determine innovative systems and tools that meeting PGS’ evolving needs.

How You Will Achieve It

Serve as the Business Owner for the PGS Learning Management System:

• Serve as the PGS business owner for the Pfizer LMS, partnering with the Enterprise Process Owner to assure the enterprise strategy effectively represents PGS needs.

• Partner with Digital, Quality, Compliance, and the sites to ensure an effective continuous improvement strategy of the LMS system and technologies.

• Actively support Regulatory and internal audits and can effectively represent the PGS LMS system.

• Represent PGS on system upgrades, assuring input to / review of user requirements, evaluation of new features / functions, execution of testing, and development of training materials.

• Sponsor the PGS PLA Community of Practice (CoP) that drives collaboration and adoption of best practices and solves system issues. Guides the team on proper escalation to CoE (center of Excellence) when support is warranted.

• Communicates with LPOs and system administrators about issues with and changes to the LMS.

• Review / approve Enterprise requests for PGS Security Roles.

• Serve as the PGS Change Network Lead for Growth & Development Learning Platform.

Build and maintain an LMS and technology strategy and roadmap that is fit for purpose:

• Partners with CoE and stakeholders to establish, manage and execute a digital learning roadmap for PGS. Puts forward business cases that support the roadmap and channels investments wisely.

• Define and implement network strategies, methods, and tools to promote effective and efficient learning solutions and technology.

• Sponsor or lead use cases/pilots for new methods and tools that improve delivery and effectiveness of training.

Provide leadership, coaching and support for the Learning Solutions and Technology team:

• Leads the group to ensure that appropriate eLearning is developed using good instructional design principles and fit for purpose tools that promote speed and efficiencies. Ensures appropriate training modalities.

• Provides guidance, support, development, prioritization and coaching to direct reports to ensure the team is delivering on objectives with high impact.

• Engages and promotes agile ways of working by looking for opportunities to cross-train within the team and more broadly in the network.

• Builds a high performing team that works synergistically with the larger QSOC team.

• Shares expertise of solutions and technology with Personnel and Training Management COE to increase knowledge of available technologies and influence direction.

Qualifications

Must-Have

• Bachelor’s Degree in education, training and development, instructional design or related fields.

• Minimum of 5 years of experience in training and development and instructional design, using multiple technologies.

• Knowledge of pharmaceutical manufacturing and regulatory compliance needed.

• From 10 to 15 years of experience leading a high performing and engaged team that is aligned to business goals/KPIs and demonstrates value.

• Ability to identify risks and need for escalation.

• Can communicate and influence at senior director or VP level.

• Demonstrated critical thinking skills and through data analytics and trends, takes an informed position.

• Continuous improvement mindset and challenges status quo.

Nice-to-Have

• Master’s Degree preferred.

  
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
 

Physical/Mental Requirements

• Ability to stand / sit for extended periods of time. 

Non-Standard Work Schedule, Travel, or Environment Requirements

• Travel up to 10% of the time; flexibility to work off hours as needed to support all regions. 

• Work Location Assignment: On Premise.

Other job details

• Last day to apply: March 29, 2024.

• Relocation assistance: No.

Relocation assistance may be available based on business needs and/or eligibility.