Total 3 Manager level Science / R&D / Research job vacancies in CB2 1UA

Tissue Diagnostic Science Manager

12 Month Fixed Term Contract or Secondment

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us.

With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing ground breaking science with the latest technology to achieve breakthroughs. Backed by investment, we are seeking to deliver 6 new molecular entities by 2025.

A place built on courage, curiosity and collaboration - we make results-oriented decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team.

Pioneers of collaborative research we have built an outstanding scientific community both internally and externally. Fusing academia and industry, we have united some of the world's foremost medical centres.

Have the opportunity to build an exciting and meaningful career as part of the team committed to improving the lives of millions with cancer.

Precision Medicine and BioSamples within AstraZeneca focuses on matching medicines to those patients who will benefit from them most and delivers companion or complementary diagnostic assays that align with the drug development process and enable personalised healthcare approaches within our clinical portfolio.

As a Manager, Tissue Diagnostics Science you will use your knowledge of tissue based diagnostic assays including immuno-histochemistry (IHC), in situ hybridization (ISH) and other ground breaking technologies and approaches (multiplexing, multi-immunofluorescence, Digital pathology and artificial intelligence etc.) to provide scientific and technical expertise to deliver innovative tissue diagnostic approaches to AstraZeneca's clinical portfolio, through strategic partnerships with leading diagnostic companies.

If successful, you would be part of multidisciplinary teams implementing and delivering diagnostic tests to match the right patients to the right drugs. Specifically, you would be:

• Delivering diagnostic testing to clinical studies as agreed with project leaders including tissue (IHC, ISH assays) diagnostic test establishment in partner laboratories, establish innovative diagnostic tests (e.g. tests relying on machine learning/AI), monitor diagnostic test data for quality control, provide scientific troubleshooting when necessary and preparation of study reports with presentation at appropriate meetings.
• Accountable for the operational, scientific and regulatory aspects of establishing and controlling diagnostic tests used to identify patients who are eligible to enter drug clinical trials.
• Performing technical due diligence of potential external partners (e.g. start-up companies, diagnostic manufacturers, laboratories) in scientific area(s) of expertise.
• Leading projects across internal and external partners in a global multi-disciplinary environment, applying scientific, technical and operational expertise.
• Accountable to scout and evaluate emerging technologies in your area of expertise aligned with mid and long term strategic priorities of Precision Medicine.
• Identify opportunities, propose solutions and work across boundaries in the scientific area(s) of expertise that will enable drug development projects and diagnostics labelling.
• Generating scientific evidence from a variety of data-types (e.g. images, real-world evidence, clinical trial data) to enable companion diagnostic test selection, regulatory submissions and diagnostic test life-cycle management.
• Delivering diagnostic data work packages to enable regulatory submission and approval inclusive of studies to enable market adoption and life cycle management, including statistical data analysis.
• Building and maintaining a knowledge of current and emerging diagnostic technologies in area of expertise.
• Accountable for the delivery of scientific evidence enabling the development of new diagnostic tests, their regulatory submissions and commercial launches.
• Driving continuous improvement in the scientific area(s) of expertise, aligned to Precision Medicine strategic objectives of increasing project success, adding value to projects and delivering better medicines to patients.
• Being accountable for the time and quality of agreed work.
• Providing updates on the progress, risks and opportunities of the agreed work to the appropriate governance bodies for review, challenge and issue resolution.
• Taking on small supervisory or skills transfer / training roles

Essential Minimum

• BSc or equivalent experience in relevant subject
• Experience of working in collaborative or multi-functional initiatives
• Excellent verbal and written communication skills
• Knowledge of tissue-based biomarker assays, such as immunohistochemistry (IHC) and/or in situ hybridisation (ISH), including troubleshooting and QC
• Operational experience of clinical trial set up, documentation and QC / monitoring of tissue testing

Desirable

• Advance degree or equivalent experience in a relevant area
• An understanding of clinical and diagnostic development and commercialisation.
• Knowledge of clinical testing procedures and applicable laboratory testing regulations such as Good Clinical Practice, CAP/CLIA, Good Clinical Practice and Quality Systems Regulation.

Why we love it

If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Here we truly understand science and apply it every day to strengthen and grow our pipeline.

This role can sit at our UK, Cambridge or Poland, Warsaw locations

Cambridge Biomedical Campus (1 position); Warsaw, Poland (1 position)

Competitive Salary & Benefits

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


We are looking for an experienced and enthusiastic communications and engagement manager to join the R&D Communications team.

You will be leading on communications and engagement projects related to the use of health data in research, with particular responsibility for delivery of communications aspects of the East of England Secure Data Environment project.

This role can either be office based (Barton House) or combined office/home based.

Produce content related to the EoE SDE and contribute to content on a variety of health-data and/or research related projects through R&D.

Identify and develop links with other health data research projects taking place on the Cambridge Biomedical Campus.

Support the development of internal and external communications, where required, by regular contact with partners, stakeholders and the R&D communications team.

Develop outputs including text, images, video and audio to reach target audiences and increase visibility with prospective followers.

Monitor new trends across the health data and translational research spaces, responding as appropriate to manage reputations.

Support the development and delivery of public engagement events, in collaboration with our partners.

Our Trust

Cambridge University Hospitals (CUH) NHS Foundation Trust comprises Addenbrooke’s Hospital and the Rosie Hospital in Cambridge. With over 11000 staff and over 1100 beds the priorities of the Trust focus on a quality service which is all about people – patients, staff and partners. Recognised as providing ‘outstanding’ care to our patients and rated ‘Good’ overall by the Care Quality Commissioner, is testament to the skill and dedication of the people who work here. CUH’s values – Together - Safe, Kind, Excellent – are at the heart of patient care, defining the way all staff work and behave. The Trust provides accessible high-quality healthcare for the local people of Cambridge, together with specialist services, dealing with rare or complex conditions for a regional, national and international population.

CUH is committed to promoting a diverse and inclusive community - a place where we can all be ourselves. We value our differences and fully advocate and support an inclusive working environment where every individual can fulfil their potential. We want to ensure our people are truly representative of all the communities that we serve. We welcome applications for all positions in the organisation irrespective of people’s age, disability, ethnicity, race, nationality, gender identity, sex, sexual orientation, religion or belief, marriage and civil partnership status, or pregnancy and maternity status or social economic background.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities.

This vacancy will close at midnight on the 4th January 2024.

Interviews will be in the week commencing 12th January 2024.

Benefits to you

We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel.

Informal discussions about the post are welcome using the details below.

We welcome applications from the Armed Forces.


This advert closes on Thursday 4 Jan 2024

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on the 4th January 2024. Interviews will be in the week commencing 12th January 2024. Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Informal discussions about the post are welcome using the details below. We welcome applications from the Armed Forces.