Total 10 Senior Executive level Education / Training job vacancies in Cambridgeshire, CB2 0QQ

Cambridge University Hospitals NHS Foundation Trust has an international reputation for high quality patient care, education and research. It plays a key role in in the Anglian region Cancer Research Network, and partners with CRUK-CI and University of Cambridge. Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


Applications are invited for a Clinical Research Fellow (ST6+/Senior) in Oncology (Gynaecologic Medical Oncology) with Cambridge University Hospitals NHS Foundation Trust.

This post is available to commence ASAP for 12 months in the first instance.

This is an exciting opportunity for a Physician with Oncology experience wishing to extend and deepen knowledge of Gynae Medical Oncology and clinical trials. Extensive experience will be gained in trial design and the management of phase I to III clinical trials, and in the facilitation of translational research at the Cancer Research UK Cambridge Institute. We run a diverse trials portfolio spanning the entire range of systemic treatment options (cytotoxic chemotherapy, targeted, biological and immunotherapy agents and viral based cancer therapies).

The post is set up to support both research and clinical duties. In order to maintain clinical experience, post holder will be expected to attend outpatient clinics, sub-specialty meetings, and ward rounds as well as support delivery of care to patients receiving treatment in clinical trials.

This post is suitable for Trainees after specialist Oncology training (or equivalent) with PhD (or equivalent).

This post would ideally suit applicants who have CCT in Clinical or Medical Oncology specialist training with evidence of participation in clinical or translational research and post-graduate research degree (PhD or equivalent).

Please note that this post does not carry Postgraduate Dean’s approval or training recognition.

Full Registration and a Licence to Practice with the General Medical Council at point of application is required.

The applicant must have demonstrable skills in listening, reading, writing and speaking in English that enable effective communication about medical topics with patients and colleagues, as set out in the GMC’s Good Medical Practice (2013).

Applications from job seekers who require skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website.

It is a requirement for skilled worker applicants, applying for entry clearance into the UK, to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) will also be subject to this requirement.

Cambridge University Hospitals NHS Foundation Trust is an Equal Opportunities Employer.

Cambridge University Hospitals NHS Foundation Trust has an international reputation for high quality patient care, education and research. It plays a key role in in the Anglian region Cancer Research Network, and partners with CRUK-CI and University of Cambridge.

Please refer to the Job description and Person specification attached for further details on the main responsibilities and duties for this post.


This advert closes on Sunday 1 Dec 2024

Your new company
You will be joining a world leading research institute based in the Cambridge area - who have a wide range of partnerships within academia and pharmaceutical & biotech companies - focusing on research within cancer.
The institution has invested heavily in equipment and lab upgrades and fosters a highly collaborative and friendly work environment, where you will be working with leading experts within cancer and biological research.They also offer very generous benefits, a flexible approach to working and make significant investment into the training and development of their staff, so there will be a number of opportunities to develop new and advance existing skills.


Your new role
You will be joining a prestigious research group working with some of the leading scientists in the genetics field carrying out research work to identify new approaches to tackle cancer.
Main responsibilities will include:

• Lead innovative research in molecular biology to uncover fundamental mechanisms related to genetic and protein functions in cancer.
• Investigate interactions between modified bases and proteins, focusing on their impact on genome functions like transcription and chromatin organisation.
• Develop new techniques to study the dynamics of modified bases and their binding proteins, utilising chemical and genetic approaches.
• Analyse genetic/genomic and other omics data sets to provide insights and use these to design future experiments.
• Explore genetic targets for synthetic lethality opportunities in cancer.
• Manage your own research projects while collaborating with others, ensuring meticulous record-keeping and resource management.
• Share your findings through presentations and publications, and help to mentor PhD students.

What you'll need to succeed
As well as strong communication and organisational skills, you should have:

• A PhD (or be nearing completion) in molecular biology, biochemistry, cancer genomics, or related fields, or significant equivalent experience
• Proficiency in molecular biology techniques, including RNA/DNA analysis, PCR, protein analysis, and western blotting.
• Advanced cloning skills, with experience in genetic engineering, vector construction, and CRISPR/Cas9 systems.
• Expertise in recombinant protein design and expression, utilising systems like E. coli, along with purification methods such as FPLC and mass spectrometry.
• Familiarity with genomic technologies like ChIP-seq, RNA-seq, and single-cell methods, preferably within oncology research, though this is not essential.

It would be an advantage to have good data analysis skills and experience using programming / scripting languages such as Python and/or R, along with tools like MATLAB and Bioconductor, however training can be provided.

What you'll get in return
An exciting opportunity to work with one of the leading research institutes in the country, excellent career and skills development, a great working atmosphere and the chance to make a real impact on cancer research.


What you need to do now
If you're interested in this role, click 'apply now' to forward an up-to-date copy of your CV, or call me on 0203 465 0057.
If this job isn't quite right for you but you are looking for a new position, please contact us for a confidential discussion on your career.

Keywords: biology, biologist, molecular, cell, gene, expression, editing, CRISPR, Cas9, recombinant, protein, NGS, genetic, genomic, cancer, cloning, vector, RNAseq, ChIPseq, research, science, pharmaceutical, biotech, drug, discovery, development, R&D, R, python

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. If you require sponsorship for a Visa to work in the UK, to avoid disappointment, please check you are not applying from a Red list country - Code of practice for the international recruitment of health and social care personnel in England - GOV.UK (www.gov.uk) This vacancy will close at midnight on 17 September 2024 Interviews are due to be held on 2 October 2024 Benefits to you At Cambridge University Hospitals, we want to do all we can to support good working days. We offer development opportunities and a wide range of benefits, including on-site leisure facilities, shopping concourse and day nurseries. Our good work programme currently includes providing reduced cost Stagecoach bus travel to and from Cambridge University Hospital site. Park and Ride bus journeys between Babraham Road and Trumpington sites are free, as is the route to and from Cambridge train station and our hospitals. We also subsidise the cost of parking on site for eligible staff. On CUH campus, hot food is available 24/7 and at a reduced cost for colleagues. Recently we launched the first of our staff pod break spaces. Located in the Deakin Centre, we have a purpose-created colleague-only caf, with free tea and coffee, a break space and private outside area for colleagues to rest, refuel and recharge. Just one of the ways we are working hard to support good working days at CUH. CUH is committed to assisting employees in achieving a good work-life balance irrespective of role or personal circumstances. Flexible arrangements may include, but are not limited to, part-time working, job-share, term-time working and flexible start and finish times. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on 25th August 2024 Interview date:- To be confirmed Due to Home Office immigration rules, a full time permanent vacancy cannot be filled by individuals on a Student visa. Therefore, please be advised that if you are a Student visa holder, we will not be able to offer you a full time permanent contract unless you have:- applied for a Graduate visa- or you will have successfully completed your course and have applied for a Graduate visa before the anticipated start date of your employment- or the Trust has agreed that they will Sponsor you as a Skilled Worker and you will complete your studies within 3 months of the anticipated start date of employment Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on 4th July 2024 Interview date:- To be confirmed Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered. We welcome applications from the Armed Forces.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

Job Title: Senior Research Associate - Synergy

Location: Cambridge, UK

Salary: £35,000 p/a

contract: 12 month FTC

A highly motivated Senior Research Associate (SRA) in protein biochemistry and molecular assays. The SRA will be responsible for the production of condensate-forming proteins and carry out compound screening using our proprietary microfluidic platform, activities that are critically important to the success of our drug-discovery program.

This role will require a good knowledge of problem-solving capability to successfully express and purify challenging protein systems from heterologous hosts. The candidate should demonstrate expertise and technical proficiency in molecular biology and protein chromatography methods. Comprehensive training will be provided for the operation of our specialized screening technologies.

Synergy, part of SRG, offer a range of scientific solutions to different Clients in the Life Sciences sector. We can offer a competitive salary, a range of excellent benefits and access to training & development opportunities within the role.

Responsibilities:

· Express and purify recombinant proteins, including cloning and construct generation.

· Problem solve and innovate to produce proteins in large scales from heterologous expression systems including insect and bacterial cells.

· Analyse data, troubleshoot technical difficulties, implement solutions, and present results regularly at team meetings.

· Maintain and implement laboratory practices to a high standard, including accurate record keeping using electronic laboratory notebook systems.

· Work effectively and collaboratively with cross-disciplinary teams to contribute to the vision, strategy, and tactics of the organization.

Requirements:

· BSc/MSc in Biochemistry, Biophysics, or a related field, or sufficient industry experience.

· Solid industry experience, working in protein biochemistry, molecular biology, or related disciplines (2-3 years).

· A demonstrated ability to design and execute recombinant protein expression and purification strategies using mammalian, insect, yeast, ba

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.