Total 41 Science / R&D / Research job vacancies in Peterborough, Cambridgeshire, PE3 9PY

We are seeking a research assistant to work within the Group of Dr Clémence Blouet at the Institute of Metabolic Science, within a programme aimed at understanding the mechanisms through which brain nutrient sensing contributes to appetite, metabolism and body weight regulation.

This position offers an ideal opportunity for motivated scientists wishing to develop their research skills in neurobiology within a world-class research environment.

In this role, you will undertake laboratory-based work and support research on mouse models. Applicants need to have the ability to use standard histological techniques, use confocal microscopy and perform image analysis. Applicants also need to have the ability to work with mouse models.

You will be expected to:

Routinely prepare samples for histological analysis
Image histology samples and perform image analysis
Develop and validate new histological, imaging and quantification protocols
Use an electronic lab book to record your lab log,
Ensure the research is carried out in accordance with good practice and in compliance with local polices and legal requirements
Contribute to laboratory-wide discussions on developments within the field
Assist in training students and other members of the laboratory.
Contribute to basic mouse assessments and colony management
Overview general laboratory management (ordering, instrument calibration, sample/reagent inventories, etc..)
To be considered for this position, you must:

Possess a BSc degree or equivalent in neuroscience, biochemistry, physiology, or a related field
Have skills in working independently to solve experimental problems.
Be self-motivated, creative, and curious
Possess excellent record-keeping, organizational, communication, and interpersonal skills
Hold a personal license from the home office
You should have experience with:

Basic molecular biology techniques
Basic mouse husbandry techniques
Basic mouse dosing procedures
Histology and imaging
Applicants should also be eligible for a Home Office Personal License

Fixed-term: The funds for this post are available until 9 January 2026 in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check, a health assessment and a security check.

We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date: 1st August 2024

Date of interview: First Week in September

What skills and experience we're looking for



Required for September 2024 or sooner, a well-qualified and enthusiastic Teacher of Mathematics to join a successful and well-resourced curriculum area.



What the school offers its staff



The school provides an exceptional in-house CPD programme to enhance career development. If you want to truly make a difference to the lives and aspirations of our students we look forward to hearing from you.



Further details about the role



Maths GCSE results are among the best in the school. 4+ 74% and 5+ 50%, Progress score 0.37, Maths and Further Maths are popular subjects post-16 and results are consistently high.



The successful candidate will be required to teach Key Stage 3, Key Stage 4



and potentially Key Stage 5. Courses offered are AQA GCSE,



AQA ‘A’ Level and Further Mathematics.



Commitment to safeguarding

Our organisation is committed to safeguarding and promoting the welfare of children, young people and vulnerable adults. We expect all staff, volunteers and trustees to share this commitment. Our recruitment process follows the keeping children safe in education guidance. Offers of employment may be subject to the following checks (where relevant): childcare disqualification Disclosure and Barring Service (DBS) medical online and social media prohibition from teaching right to work satisfactory references suitability to work with children You must tell us about any unspent conviction, cautions, reprimands or warnings under the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975.

What skills and experience we're looking for

Arthur Mellows is located in the village of Glinton on the outskirts of Peterborough. The school is very successful and over-subscribed. Behaviour is excellent and students are keen to learn.

We are looking for a Science Technician to join our highly successful team where student outcomes are paramount. Working in the Science Prep room you will provide apparatus and materials for teaching staff to enable them to deliver Science lessons

What the school offers its staff

This friendly team work closely together to support the large Science Department. Consistent and effective communication are required together with the ability to use own initiative.

Commitment to safeguarding

Our organisation is committed to safeguarding and promoting the welfare of children, young people and vulnerable adults. We expect all staff, volunteers and trustees to share this commitment. Our recruitment process follows the keeping children safe in education guidance. Offers of employment may be subject to the following checks (where relevant): childcare disqualification Disclosure and Barring Service (DBS) medical online and social media prohibition from teaching right to work satisfactory references suitability to work with children You must tell us about any unspent conviction, cautions, reprimands or warnings under the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975.

The Opportunity

Due to exponential growth, we are looking for four new Actuarial Analysts to join our Change and Transformation team to support with the delivery of several transformation projects across our clients. This involves providing requirement analysis, modelling and testing of product calculations and other responsibilities.

This is a fantastic opportunity for those looking to develop their career and skills within Actuary, with continuing support from us to complete your examinations, as well as providing opportunities to progress to more senior positions.

Locations: Peterborough and Bristol, but other locations considered

You'll be:

• Interpreting actuarial and product information to ensure accuracy of calculations.
• Responsible for the analysis, identification and collation of static data required for calculations.
• Responsible for the specification of Expects Results (ERs), and test conditions to test calculations.
• Owning the resolution of issues and liaising with actuarial, IT developers, product experts, TCS BaNCS and clients to drive solution outcomes.
• Applying data analysis methods and techniques to investigate and validate complex calculation models.

You should apply if you are:

• Working towards IFoA qualification exams.
• Experienced working within the Life and Pensions sector.
• Able to analyse vast quantities of data under time constraints.
• Proficient in Microsoft Excel.
• Systematic, disciplines and analytical in your problem-solving approach.

The Perks

• 25 days holidays + 8 bank holidays
• Discretionary annual bonus
• Company pension scheme membership
• Gain professional accreditation on completion at no extra cost through our bespoke 24/7 professionally accredited online learning and development tools
• Access to our Confidential Helpline is available to be used by you and your family
• Develop your career through a wider global organisation of the TCS family

TEACHER OF SCIENCE


Required for September 2024 an enthusiastic science teacher to join a successful and well-resourced curriculum area.
Applications are welcomed from newly qualified teachers and experienced teachers.

The successful candidate will be required to teach both Key Stage 3 and
Key Stage 4 Science, as well as your specialist area at KS5.

Separate Science GCSE results are among the best in the school.
The Sciences are popular subjects post-16.
We are looking for teachers who are enthusiastic and passionate about teaching and determined to make a difference to the lives of our students.

Jack Hunt is an oversubscribed 11-18 vibrant, multi ethnic co-educational,
comprehensive school with outstanding community cohesion.

The school provides an exceptional in-house CPD programme to enhance
career development. If you want to truly make a difference to the lives and aspirations
of our students we look forward to hearing from you.

The Governing Body of Jack Hunt School and the Board of Trustees are committed to safeguarding and promoting the welfare of children and young people.

For further details and to complete an online application visit www.PKAT.co.uk/vacancies



Closing date: Monday 13 May 2024 at 9.00 am

Please see detailed Job Description and Person Specification for more information regarding this role.

Applications are invited for a Research Nurse to join the ACED Clinic Team at the Early Cancer Institute (https://www.earlycancer.cam.ac.uk/), Department of Oncology. The Institute's goal is to develop, validate and establish novel, highly effective early cancer diagnostic and intervention methodologies. The Research Nurse will perform and manage translational research studies for the Cambridge International Alliance for Cancer Early Detection (ACED) Clinic Team. They will be responsible for a number of cross-disciplinary research studies in a clinical environment, including recruiting participants to the ACED cohort bioresource. Applicants must have a professional nursing qualification and post-registration research experience in performing clinical studies. The post holder should demonstrate flexibility and adaptability to help meet the responsibilities of the role. Knowledge of research methodology, ethics and research governance of clinical studies is also essential. Experience in clinical research studies for the early detection of cancer would be an advantage.

This post is available immediately.

Informal enquiries about this post may be directed to Alice Groves, Oncology Department, Email:ag2188@cam.ac.uk Tel: 01223 763353

Fixed-term: The funds for this post are available for 1 year in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a Disclosure and Barring Service check (enhanced with children and adults' barred lists). This appointment also requires NMC Registration and a Research Passport application.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

This is an integrated appointment between the University and Cambridge University Hospitals NHS Foundation Trust ("NHS Trust"). You will therefore also be issued with an Honorary Research Contract by the NHS Trust. You should be aware that if your contract with the NHS Trust is terminated your employment with the University will be terminated, and vice versa.

Please ensure that you upload a covering letter, CV and a completed Additional Information for Allied Health Professionals form in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date: 28th April 2024
Date of interview: To be confirmed

The Opportunity

Due to exponential growth, we are looking for four new Actuarial Analysts to join our Change and Transformation team to support with the delivery of several transformation projects across our clients. This involves providing requirement analysis, modelling and testing of product calculations and other responsibilities.

This is a fantastic opportunity for those looking to develop their career and skills within Actuary, with continuing support from us to complete your examinations, as well as providing opportunities to progress to more senior positions.

Locations: Peterborough and Bristol, but other locations considered

You'll be:

• Interpreting actuarial and product information to ensure accuracy of calculations.
• Responsible for the analysis, identification and collation of static data required for calculations.
• Responsible for the specification of Expects Results (ERs), and test conditions to test calculations.
• Owning the resolution of issues and liaising with actuarial, IT developers, product experts, TCS BaNCS and clients to drive solution outcomes.
• Applying data analysis methods and techniques to investigate and validate complex calculation models.

You should apply if you are:

• Working towards IFoA qualification exams.
• Experienced working within the Life and Pensions sector.
• Able to analyse vast quantities of data under time constraints.
• Proficient in Microsoft Excel.
• Systematic, disciplines and analytical in your problem-solving approach.

The Perks

• 25 days holidays + 8 bank holidays
• Discretionary annual bonus
• Company pension scheme membership
• Gain professional accreditation on completion at no extra cost through our bespoke 24/7 professionally accredited online learning and development tools
• Access to our Confidential Helpline is available to be used by you and your family
• Develop your career through a wider global organisation of the TCS family

Tissue Diagnostic Science Manager

12 Month Fixed Term Contract or Secondment

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us.

With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing ground breaking science with the latest technology to achieve breakthroughs. Backed by investment, we are seeking to deliver 6 new molecular entities by 2025.

A place built on courage, curiosity and collaboration - we make results-oriented decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team.

Pioneers of collaborative research we have built an outstanding scientific community both internally and externally. Fusing academia and industry, we have united some of the world's foremost medical centres.

Have the opportunity to build an exciting and meaningful career as part of the team committed to improving the lives of millions with cancer.

Precision Medicine and BioSamples within AstraZeneca focuses on matching medicines to those patients who will benefit from them most and delivers companion or complementary diagnostic assays that align with the drug development process and enable personalised healthcare approaches within our clinical portfolio.

As a Manager, Tissue Diagnostics Science you will use your knowledge of tissue based diagnostic assays including immuno-histochemistry (IHC), in situ hybridization (ISH) and other ground breaking technologies and approaches (multiplexing, multi-immunofluorescence, Digital pathology and artificial intelligence etc.) to provide scientific and technical expertise to deliver innovative tissue diagnostic approaches to AstraZeneca's clinical portfolio, through strategic partnerships with leading diagnostic companies.

If successful, you would be part of multidisciplinary teams implementing and delivering diagnostic tests to match the right patients to the right drugs. Specifically, you would be:

• Delivering diagnostic testing to clinical studies as agreed with project leaders including tissue (IHC, ISH assays) diagnostic test establishment in partner laboratories, establish innovative diagnostic tests (e.g. tests relying on machine learning/AI), monitor diagnostic test data for quality control, provide scientific troubleshooting when necessary and preparation of study reports with presentation at appropriate meetings.
• Accountable for the operational, scientific and regulatory aspects of establishing and controlling diagnostic tests used to identify patients who are eligible to enter drug clinical trials.
• Performing technical due diligence of potential external partners (e.g. start-up companies, diagnostic manufacturers, laboratories) in scientific area(s) of expertise.
• Leading projects across internal and external partners in a global multi-disciplinary environment, applying scientific, technical and operational expertise.
• Accountable to scout and evaluate emerging technologies in your area of expertise aligned with mid and long term strategic priorities of Precision Medicine.
• Identify opportunities, propose solutions and work across boundaries in the scientific area(s) of expertise that will enable drug development projects and diagnostics labelling.
• Generating scientific evidence from a variety of data-types (e.g. images, real-world evidence, clinical trial data) to enable companion diagnostic test selection, regulatory submissions and diagnostic test life-cycle management.
• Delivering diagnostic data work packages to enable regulatory submission and approval inclusive of studies to enable market adoption and life cycle management, including statistical data analysis.
• Building and maintaining a knowledge of current and emerging diagnostic technologies in area of expertise.
• Accountable for the delivery of scientific evidence enabling the development of new diagnostic tests, their regulatory submissions and commercial launches.
• Driving continuous improvement in the scientific area(s) of expertise, aligned to Precision Medicine strategic objectives of increasing project success, adding value to projects and delivering better medicines to patients.
• Being accountable for the time and quality of agreed work.
• Providing updates on the progress, risks and opportunities of the agreed work to the appropriate governance bodies for review, challenge and issue resolution.
• Taking on small supervisory or skills transfer / training roles

Essential Minimum

• BSc or equivalent experience in relevant subject
• Experience of working in collaborative or multi-functional initiatives
• Excellent verbal and written communication skills
• Knowledge of tissue-based biomarker assays, such as immunohistochemistry (IHC) and/or in situ hybridisation (ISH), including troubleshooting and QC
• Operational experience of clinical trial set up, documentation and QC / monitoring of tissue testing

Desirable

• Advance degree or equivalent experience in a relevant area
• An understanding of clinical and diagnostic development and commercialisation.
• Knowledge of clinical testing procedures and applicable laboratory testing regulations such as Good Clinical Practice, CAP/CLIA, Good Clinical Practice and Quality Systems Regulation.

Why we love it

If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be. Here we truly understand science and apply it every day to strengthen and grow our pipeline.

This role can sit at our UK, Cambridge or Poland, Warsaw locations

Cambridge Biomedical Campus (1 position); Warsaw, Poland (1 position)

Competitive Salary & Benefits

Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

***Please note we are only able to accept applications from those with a live UK NMC registration as we are unable to support OSCE at this time***

Have you considered applying your research skills and knowledge in practice?

Our research team is welcoming to a Registered Nurse/Practitioner to join the research projects spanning across the Emergency Medicine and Surgical Divisions. These divisions cover a range of specialities and therefore applicants are welcome from a broad range of specialities within these divisions. You will be based at Peterborough City Hospital with cross-site working at Hinchingbrooke Hospital.

Your research skills and knowledge acquired through proven continuous personal and professional development will add great value to our research team formed of Nurses, Practitioners, Clinical Trials assistants, R&D Office staff, local clinicians, and relevant research networks aiming to develop and deliver high quality research activity across the Trust services.

As a Research Nurse/Practitioner, you will assist with participant identification and recruitment, obtaining informed consent from patients, organise patient visits, completion of case report forms and maintenance of study documentation according to good clinical practice.

You will demonstrate excellent communication, organisational, and time management skills.

Applicants from all specialties are welcome. If you are passionate about innovation and change, join us at North West Anglia NHS Trust!

You will be working effectively within our clinical research team across the Trust supporting the staff, manage caseload of patients.

You will maintain effective communication with patients, carers and professionals to ensure service delivery. You will provide research information to patients and their relatives, and act as a resource and support to them, explaining practical aspects of clinical research.

Patients’ consent in research is very important. Therefore, you facilitate the informed consent process, in compliance with Good Clinical Practice (GCP), ensuring that the patient and relatives fully understand the nature of the research.

A main responsibility of your role will be ensuring that the study-specific investigations are undertaken as required by the research protocol, to ensure safety of study participants safety to enter the study.

As part of your research duties, you will monitor treatment toxicity/side effects and ensure changes to treatment as required by the research protocol. You will arrange collection of blood and any other research samples required as part of the clinical research, and ensure safe and appropriate storage of specimens in conjunction with local clinical and nursing teams, phlebotomy and laboratory staff.

We are strongly encouraging you to contact Susan O'Sullivan, Senior Research Nurse on 01733 676981 or email s.osullivan1@nhs.net for an informal chat about the role or to arrange a visit to learn more about what the role would involve.

We are committed to ensure a work-life balance to all our staff by offering full time and part time roles, flexible working hours on a shift pattern to fit around your family life.
We welcome and encourage applications from people of all backgrounds. We particularly encourage applications from disabled, Black, Asian and Minority Ethnic (BAME) and candidates form our local communities.
Benefits to you
• 27 days annual leave for new starters, rising to 29 days after five years of service and 33 days after 10 years of service, plus 8 Bank Holidays (pro-rata for part time staff);
• NHS Pension Scheme:
• Flexible working opportunities;
• Increased hourly rates for unsociable hours e.g. night shifts, weekends, bank holidays;
• Career development and training;
• Wellbeing support and activities;
• In-house physiotherapy Service;
• On-site canteens with subsidised meals;
• Subsidised staff parking (currently free).
• Free Stagecoach Bus Travel to and from work within Cambridgeshire and Peterborough

The post holder will assist with participant identification and recruitment, obtaining informed consent from patients and will have responsibility for organising patient visits, collection and processing of patient samples, completion of case report forms and maintenance of study documentation according to Good Clinical Practice (ICH -GCP).

You will have experience working in either the Surgical or EMED divisions and ideally be familiar with their systems. Clinical research experience within the NHS is desirable but full training and mentoring will be provided.

The post holder will assist with participant identification and recruitment, obtaining informed consent from patients and will have responsibility for organising patient visits, collection and processing of patient samples, completion of case report forms and maintenance of study documentation according to Good Clinical Practice (ICH -GCP).



Please see attached Job Description and Person Specification for further details.


This advert closes on Wednesday 17 Jan 2024

Job Title: Senior Research Associate - Synergy

Location: Cambridge, UK

Salary: £35,000 p/a

contract: 12 month FTC

A highly motivated Senior Research Associate (SRA) in protein biochemistry and molecular assays. The SRA will be responsible for the production of condensate-forming proteins and carry out compound screening using our proprietary microfluidic platform, activities that are critically important to the success of our drug-discovery program.

This role will require a good knowledge of problem-solving capability to successfully express and purify challenging protein systems from heterologous hosts. The candidate should demonstrate expertise and technical proficiency in molecular biology and protein chromatography methods. Comprehensive training will be provided for the operation of our specialized screening technologies.

Synergy, part of SRG, offer a range of scientific solutions to different Clients in the Life Sciences sector. We can offer a competitive salary, a range of excellent benefits and access to training & development opportunities within the role.

Responsibilities:

· Express and purify recombinant proteins, including cloning and construct generation.

· Problem solve and innovate to produce proteins in large scales from heterologous expression systems including insect and bacterial cells.

· Analyse data, troubleshoot technical difficulties, implement solutions, and present results regularly at team meetings.

· Maintain and implement laboratory practices to a high standard, including accurate record keeping using electronic laboratory notebook systems.

· Work effectively and collaboratively with cross-disciplinary teams to contribute to the vision, strategy, and tactics of the organization.

Requirements:

· BSc/MSc in Biochemistry, Biophysics, or a related field, or sufficient industry experience.

· Solid industry experience, working in protein biochemistry, molecular biology, or related disciplines (2-3 years).

· A demonstrated ability to design and execute recombinant protein expression and purification strategies using mammalian, insect, yeast, ba

Carbon60, Lorien & SRG - The Impellam Group STEM Portfolio are acting as an Employment Business in relation to this vacancy.