Total 76 Science / R&D / Research job vacancies in Cambridge, CB2 1QA

Role Summary

Pfizer’s Machine Learning Hub is seeking a passionate, creative, and experienced machine learning researcher to design and implement new machine learning tools to accelerate drug discovery. As a member of our Machine Learning Research team, you will design new approaches to derive insights from Pfizer’s proprietary data and external datasets to generate testable hypotheses across the drug discovery continuum with a focus on extracting biological knowledge. The individual will also design, establish, and manage internal and external collaborations to advance Pfizer’s ML capabilities. The ideal candidate should have an outstanding scientific reputation in the field of machine learning research for computational biology and a demonstrated passion for solving biological problems relevant to drug discovery. Our team is located in Cambridge, MA, USA and Berlin, Germany and this role can accommodate an exceptional candidate in either location.

Role Responsibilities

Principal downstream application domains include indication expansion, target identification, disease mechanism elucidation, and partnering with practitioners in these areas to advance the state-of-the-art.

• Development and implementation of advanced machine learning models specifically designed for analyzing heterogeneous biological data. This includes data from genomics, proteomics, metabolomics, and other biological sources.
• Advance the internal machine learning tech stack to cope with spurious correlation, obscuring variation and inherent multimodality of biomedical, chemical, and ‘omics data
• Research, design and implement learning algorithms for analysis problems related to drug discovery
• Be an active member of a highly interdisciplinary team
• Conceive, execute and evaluate studies and experiments, interpret the results and present them to scientist in other functions
• Strengthen external visibility and scientific excellence through publishing / presenting work in reputed journals and conference/workshop venues and engaging with the scientific community

Qualifications

• Formal training in Biology, Computational Biology, Statistics, Machine Learning, or a related technical discipline
• PhD and 2+ years of relevant research experience in developing machine/deep learning-based solutions and a sincere interest for computational life sciences
• Hands-on experience in handling, processing, integrating, and analyzing large heterogenous biological data sets related to industrial drug discovery research (e.g., sc/snRNAseq, ATAC-seq, genomics, proteomics, etc.)
• Proven expertise in developing machine learning for computational biology
• Highly creative person with outstanding problem-solving skills to tackle complex analysis tasks in a timely fashion
• Strong publication record and demonstrated contributions to the field
• Solid expertise with ML libraries such as PyTorch, Lightning is mandatory! Programming skills in Python must be top-notch. Experience with relevant libraries of the Python scientific stack is a big plus.
• Familiarity with GPU computing both on-premises and on cloud platforms
• Fluency with common version control tools and collaborative coding
• Passion and curiosity for data and proven ability to take ideas from prototype to production
• Strong interpersonal skills, distinct collaborative attitude, excellent written and verbal communication

PHYSICAL/MENTAL REQUIREMENTS

Ability to perform mathematical calculations and ability to perform complex data analysis. Relocation support available.

The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Information & Business Tech

Disclaimer:

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this classification. They are not intended to be construed as an exhaustive list of all responsibilities, duties and skills required of employees assigned to this position. Avantor is proud to be an equal opportunity employer.

Dare to go further in your career. Join our global team of 14,000+ associates whose passion for discovery and determination to overcome challenges relentlessly advances life-changing science.
 
The work we do changes people's lives for the better. It brings new patient treatments and therapies to market, giving a cancer survivor the chance to walk his daughter down the aisle. It enables medical devices that help a little boy hear his mom's voice for the first time. Outcomes such as these create unlimited opportunities for you to contribute your talents, learn new skills and grow your career at Avantor.
 
We are committed to helping you on this journey through our diverse, equitable and inclusive culture which includes learning experiences to support your career growth and success. At Avantor, dare to go further and see how the impact of your contributions set science in motion to create a better world. Apply today!

EEO Statement:

We are an Equal Employment/Affirmative Action employer and VEVRAA Federal Contractor. We do not discriminate in hiring on the basis of sex, gender identity, sexual orientation, race, color, religious creed, national origin, physical or mental disability, protected Veteran status, or any other characteristic protected by federal, state/province, or local law.

If you need a reasonable accommodation for any part of the employment process, please contact us by email at recruiting@avantorsciences.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

We will use the personal information that you have submitted to us in order to consider your application for the relevant role.
 

Your privacy is important to us. Please click here for our Privacy Policy which explains the purposes for which we will use your personal information and the ways in which we will handle and retain your information. It also explains the rights you have in relation to your information, and how to contact us with any queries or requests.

3rd Party Non-Solicitation Policy:

By submitting candidates without having been formally assigned on and contracted for a specific job requisition by Avantor, or by failing to comply with the Avantor recruitment process, you forfeit any fee on the submitted candidates, regardless of your usual terms and conditions. Avantor works with a preferred supplier list and will take the initiative to engage with recruitment agencies based on its needs and will not be accepting any form of solicitation.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on 24th March 2024 Interviews are due to be held on 8th April 2024 Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases alternative working hours will be considered. We welcome applications from the Armed Forces.

ROLE SUMMARY

The Internal Medicine Research Unit (IMRU) is committed to finding cures for metabolic diseases and related complications. Our goal is to build a research team of driven scientists focused on developing a deep mechanistic understanding of the metabolic pathways driving obesity, cardiovascular disease, diabetes, and renal disease. Apply scientific and technical expertise to drug discovery programs to impact the future of new drug candidate development. The aim is to recruit a scientifically and technically strong research scientist proficient in in vivo and in vitro metabolic research models, with the ultimate goal of developing effective therapies.
 

ROLE RESPONSIBILITIES

• Conceptualize and design experiments.

• Organize and conduct in vitro/ in vivo/ ex vivo studies independently (including preparation, data collection, interpretation, and presentation).

• Maintain awareness of scientific and technical developments in the field.

• Author manuscripts for quality publications in top-tier journals.

• Interface with an interdisciplinary team of scientists in the Internal Medicine Research Unit and engage in both target exploration and driving established projects in our portfolio.

• Quantify and translate experimental results to advance the understanding of how metabolic pathways and complex physiological systems are altered by diseases and how they respond to therapeutic interventions.

• Maintenance of laboratory notebook records and adherence to safety policies is strictly required.

QUALIFICATIONS

• PhD with a minimum of 2 years of post-doc experience.

• Experience in obesity-related physiology is required (examples, CNS regulation of energy balance, muscle or adipose metabolism/function).

• Expertise in cell biology and physiology with emphasis on metabolism and signaling pathways is essential.

• Experience working with GPCRs and associated pathways is a plus but not required.

• A successful track record of scientific achievements through scientific publications and presentations.

• Candidate should be able to review literature to formulate new ideas and have the ability to work independently as well as with an interdisciplinary team of scientists in a highly collaborative environment.

• The candidate will have daily interactions with a team of creative and innovative scientists in a supportive environment.

• Excellent communication and interpersonal skills are essential.

  
PHYSICAL/MENTAL REQUIREMENTS

In vivo vivarium work

Relocation support available

Work Location Assignment: On Premise

The annual base salary for this position ranges from $88,300.00 to $147,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Research and Development

ROLE SUMMARY

The purpose of the Senior Director of Clinical Research role is to coordinate and lead the development of first in man (FIH), proof of mechanism (POM), proof of clinical activity (SoCA) and proof of concept (PoC) and dose ranging studies for novel biological and small molecule therapies in Neurology focused programs. 

• The Senior Director of Clinical Research will be responsible for the Phase 2, PoM and SoCA trial designs and implementation of the study in collaboration with Pfizer development operations and the project team to meet enrollment and study delivery timelines.  The clinical study lead will be the primary liaison for investigators who have enrollment or extraordinary protocol issues that require escalation and may need to conduct study site visits to ensure timely delivery of the study.
• The individual will be involved with a focus on clinical drug activities from discovery research through PoM, SoCA and PoC studies. They will be a key member on project teams to collaborate with Early Clinical Development (ECD) and ensure seamless transition of the new asset to the Pfizer Global Product Development (GPD) for Ph3 development.

ROLE RESPONSIBILITIES

The Senior Director of Clinical Research will develop a disease specific global network of potential investigators and key opinion leaders (KoL) for the new therapeutic before PoM, SoCA or POC trial conception to assist in trial design, as well as management and recruitment of study, analysis, interpretation and presentation of results. Design PoM, SoCA or POC studies in consultation with KOLs and Pfizer project team members (Stats, Clin Pharm, Regulatory, Operations, etc.).

• Develop the primary and secondary endpoints for efficacy and safety and contribute to the precision medicine and biomarker strategy as well as to the biostatistics analytic plan that is aligned with the transition target product profile.
• Sit on project teams from FIH/POM/SOCA through POC trial completion to ensure that clinical development strategies are in place, being implemented and are contributing to key development milestones, e.g., start-up and delivery of PoM, SOCA and PoC trials.
   
• Accountable for safety across the study, including regular review of safety data (including but not limited to serious adverse events) and response to safety issues.
• Provide leadership to the clinical function in preparation of critical documents, including but not limited to clinical protocol, clinical development plan, investigator brochure, statistical analysis plan and regulatory documents.
• Expand the culture of collaboration between the clinical team and partners in the Inflammation and Immunology Research Unit (I&I RU) (Discovery, Pre-clinical and Systems Immunology), Clinical Pharmacology and Bioanalytics, Statistics, and Research and Developments (PRD) teams by maintaining open communications and ensuring successful program transitions. Foster a transparent environment that encourages strong trust between teams, sub-teams, and leaders.
   
• Sit on project teams from FIH/POM/SOCA through POC trial completion to ensure that clinical development strategies are in place, being implemented and are contributing to key development milestones, e.g., start-up and delivery of PoM, SOCA and PoC trials.
   
• Accountable for safety across the study, including regular review of safety data (including but not limited to serious adverse events) and response to safety issues.

• Provide leadership to the clinical function in preparation of critical documents, including but not limited to clinical protocol, clinical development plan, investigator brochure, statistical analysis plan and regulatory documents. Expand the culture of collaboration between the clinical team and partners in the I&I RU and PRD by maintaining open communications between the two groups and ensuring successful program transitions.

• Foster a transparent environment that encourages strong partnerships and mutual trust between teams, sub-teams, and leaders.
   

• Coordinate with other clinical research activities in the I&I RU and greater PRD organization.

• Maintain up-to-date knowledge of scientific and clinical published literature in relevant therapeutic areas including the key clinical development issues.
   

Develop effective collaborations with research project leaders and projects team members, including biostatistics, regulatory affairs, clinical pharmacology, clinical scientists and development operations.
Develop effective collaborations with key PRD partners in design of POC studies and develop target clinical goals to benchmark success of POC and SoCA studies. 

Work on transition team with Late-stage development colleagues to analyze and interpret final POC clinical data in achieving study objectives and develop the phase 3 clinical strategy to support seamless transfer of the asset to the respective Phase3 team.

Establish relationships with external experts, consultants, opinion leaders, regulators and disease specific investigator networks.

The applicant will have the opportunity to participate in strategic assessment of I&I RU portfolio, and Business Development activities.

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

QUALIFICATIONS

Education: Requires MD or MD/PhD, neurology specialty required, but other specialists with experience in neurology clinical trials will be considered.

Technical Skills: Experience in generating hypothesis-driven research investigations.

Five or more years of experience in biopharmaceutical sponsored clinical research, with a minimum of two in neurology. Biopharmaceutical experience as a medical monitor and clinical lead across therapeutic areas is desirable.

Good understanding of relevant areas such as biostatistics, regulatory, clinical pharmacology, pre-clinical toxicology, pharmacogenomics and biomarker-based approaches.

Ability to analyze and interpret complex datasets.

Ability to operate with a sense of pace and urgency in matrixed project teams.

Exercises initiative in meeting goals and drives innovation in projects.
 

Demonstrated scientific productivity (publications, abstracts, etc.).

Good communication and presentation skills as well as proven scientific writing skills.

This role is relocation eligible.

The annual base salary for this position ranges from $253,800.00 to $423,000.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Medical

The Role:

We are seeking a talented and experienced Director to lead our in vivo pharmacology research team. The successful candidate will play an integral role across our oncology research groups, overseeing the development of relevant in vivo animal and cell models, and the design and execution of pharmacology studies to propel our pre-clinical research and early development oncology pipeline in addition to Translational initiatives, such as in vivo combination evaluations. The Director will manage all internal and/ or external in vivo workflows, collaborating with various teams within Moderna, including Cancer Vaccine Research, Immuno-Oncology Research, and Research Operations. The ideal candidate will be a proven and effective team leader and people manager, highly collaborative team player, possess excellent communication skills, have a proven track record of independent research achievements, and bring innovative approaches to further our mission.

Here’s What You’ll do:

• Direct the execution and analysis of in vivo pharmacology studies that support oncology programs and platform initiatives

• Develop and refine in vivo murine tumor models and study protocols, ensuring compliance with regulatory, ethical, and quality standards; including serving as Principal Investigator on internal in vivo pharmacology protocols

• Identify new tumor models and new techniques that will further advance mRNA therapies

• Work closely with internal teams to optimize in vivo study designs and oversee their execution, whether conducted in-house or through external partners

• Establish and maintain partnerships with Contract Research Organizations (CROs), industry partners and academic institutions for all in vivo studies

• Manage the analysis, review, and summary of in vivo pharmacology data to ensure robustness as well as integration into big picture considerations

• Contribute to and co-author scientific reports for inclusion in regulatory submissions, internal and external presentations

• Lead and allocate team resources and timelines to ensure the efficient progression of studies and achievement of objectives across multiple programs and oncology-focused teams

Here’s What You’ll Bring to the Table:

• Advanced degree in Pharmacology, Oncology, or a related scientific field, with a PhD or DVM and at least 9+ years relevant experience

• Demonstrated expertise in in vivo pharmacology within oncology drug discovery and early development, preferably with a focus on nucleic acid therapeutics and vaccines

• Deep knowledge of immuno-oncology including current and emerging standards of care to inform forward translational studies

• Experienced in the creation and use of diverse in vivo cancer models for efficacy and PK/PD studies, including advanced local, systemic, disseminated, and orthotopic syngeneic, xenograft and genetically engineered murine models

• Knowledge in overseeing relevant cell model development to be deployed in vivo

• Highly experienced in in vivo study management, including pharmacological agent administration via IV, IP, SC, iTu, IM, and PO dosing routes including vaccination protocols; regular health and tumor growth monitoring; bioluminescence/fluorescence imaging using IVIS systems; necropsy and tissue collections

• Experienced in authoring, implementing and ensuring compliance to study protocols under IACUC guidelines

• Ability to mentor and develop junior scientists and research associates, and guide teams to successfully conduct in vivo studies, trouble shoot, and grow technically and scientifically

• Skilled in outsourcing studies and fostering productive relationships with CROs and/or academic collaborators

Additional Preferred Qualifications:

• Experience with cell line engineering, humanized models, or surgical/ resection models  

• Familiarity with regulatory guidelines and Good Laboratory Practice (GLP) standards

• Experience with bioinformatics tools relevant to pharmacology and oncology research

•  Facility with data analysis software tools such as GraphPad Prism

• Exceptional organizational abilities, attention to detail, scientific adaptability, and a results-driven approach

• Superior written and verbal communication skills, with the capacity to effectively engage with multiple teams

• A respectful, inclusive, and collaborative mindset, complemented by boldness, creativity, curiosity, and relentlessness

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at leavesandaccommodations@modernatx.com.  (EEO/AAP Employer) 

#LI-MBB1

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Reporting to CSO, External Research Ventures of Moderna, the Senior Director (SD) of Pulmonary Research is responsible for overseeing our therapeutic pulmonary research projects as well as leading and managing our external pulmonary research collaborations.  The SD of Pulmonary Research will be responsible for building our internal pulmonary capabilities and expertise, overseeing mRNA drug discovery projects into preclinical development, and driving the strategy for this emerging therapeutic area.  The SD will work closely with multiple internal stakeholders across functions including Platform, Nonclinical Sciences, Translational, Clinical Development, and R&D Strategy in addition to key external stakeholders involved in our external collaborations.  This is a superb opportunity for a highly motivated leader with pulmonary drug discovery expertise to join our dynamic team and impact our early pipeline.

Here’s What You’ll Do:

• Build and establish internal pulmonary capabilities and expertise to enable the inhaled pulmonary modality and therapeutics area
• Lead and direct a range of internal pulmonary therapeutic research projects.  Define objectives for research projects and ensure high-quality execution of these projects, including oversight of assays, study designs, and data
• Advance pulmonary therapeutic research projects into early development
• Oversee and manage relationships with external partners and collaborators.  Serve as Program Lead for external collaboration, effectively managing a large cross-functional internal team and working closely with external stakeholders to scientifically direct collaborations
• Mentor and have direct management responsibilities for the pulmonary research team
• Stay up-to-date with the latest scientific advances in pulmonary research and identify opportunities to incorporate new research methods and technologies
• Promote cross-functional collaboration across the organization
• Effectively communicate research progress, challenges and results to a variety of stakeholders, including teams across R&D organizations

Here’s What You’ll Bring to the Table:

• Ph.D. in pulmonary pharmacology, respiratory medicine, or related field with 12 years of relevant experience in pulmonary research in industry setting
• Strong pulmonary physiology and pharmacology experience
• Excellent leadership and team building skills.
• Strong track record driving discovery projects into early development and leading successful research teams and projects
• Proven ability to oversee and manage strategic partnerships and collaborations.
• Deep understanding of the scientific aspects of drug discovery and development
• Excellent leadership and team building skills.
• Strong written and oral communication skills scaling through all levels of the organization, including senior management.
• Strong leadership skills and an ability to collaborate productively across multiple cross-functional project teams are paramount.
• Ability to thrive in a fast-paced environment; ability to adapt to changes with demonstrated flexibility to pivot as warranted and needed.
• Acts with urgency with the understanding that actions today compound lives saved tomorrow.
• Acts like an owner, obsesses over learning, questions convention, and strives to push past possible.
• Scientific rigor & commitment to excellence and innovation.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at leavesandaccommodations@modernatx.com.  (EEO/AAP Employer) 

#LI-MBB1

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The Role

Moderna continues to leverage its novel mRNA platform to expand the R&D portfolio and open new therapeutic applications for mRNA across diseases and therapeutic areas. R&D Strategy plays a crucial role for Moderna to achieve its mission to deliver the greatest possible impact to people through mRNA medicines by supporting critical research and development decisions.

The R&D Strategy team operates across research and development to provide analysis and guidance from discovery through development. The team executes a portfolio of strategy projects comprised of:

• Discovery strategy to provide a scientific and business assessment of discovery concepts and novel applications of mRNA

• Program strategy to drive research, preclinical and clinical development decision-making for specific programs

• Portfolio strategy to set R&D priorities and objectives 

The Senior Director, R&D Strategy will be responsible for a collection of strategy projects focused around one or more key pillars of R&D and enterprise strategy (e.g., respiratory vaccines, cancer vaccines, rare metabolic therapies, next generation pipeline and platform). This person will act as a critical integrator across the R&D portfolio to identify and drive towards R&D value catalysts through prioritization and sequencing of programs and resources.

Here’s What You’ll Do

• Generate, prioritize and advance an agenda of discovery, program and portfolio strategy projects: deliver and action the most complex and cross-functional R&D questions

• Discovery Strategy: In partnership with research leadership, identify novel mRNA applications and modalities through integrated assessment of biological, clinical and market factors

• Program Strategy: In collaboration with program leadership, drive integrated discovery, preclinical, early-development and development strategy. Influence program strategy to align with the integrated R&D Strategy; identify and advance portfolio value catalysts

• Portfolio Strategy: Integrate portfolio and program perspectives into enterprise strategy, contributing to long-range planning, objective setting, and portfolio prioritization

• Be a trusted advisor and thought partner for Program Leadership and the R&D Leadership Team

• Maintain an enterprise view across research, development, manufacturing and commercial

• Additional duties as may be assigned from time to time

Here’s What You’ll Need (Minimum Qualifications)

• 12+ years of experience working for a clinical- or commercial-stage pharmaceutical/biotech company in strategy or corporate development, or similar experience in a professional services or investment capacity (e.g., management or strategy consulting, investment banking, or venture capital)

• PhD, MD, or PharmD preferred, with an understanding of drug development and value creation in the biopharmaceutical industry, and commitment to learn about the science behind our platform technology

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Ability to perform and synthesize in-depth analyses of indications, products, and therapeutic areas, to integrate analysis and broader context into a recommendation, and to defend recommendation in a respectful, objective manner

• Advanced verbal and written communication skills to deliver a compelling narrative/message to senior stakeholders in the organization

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes 
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  •    Vacation, sick time and holidays
  •    Volunteer time to participate within your community
  •    Discretionary year-end shutdown
  •    Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. 

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at leavesandaccommodations@modernatx.com.  (EEO/AAP Employer) 

#LI-MBB1

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Job Title

R&D Senior Software Architect - Medical Device / Motion Control (Cambridge, MA)

Job Description

R&D Senior Software Architect – Medical Device / Motion Control (Cambridge, MA)

Breakthrough Innovation Teams (BRITE) are the embodiment of Philips' approach to driving breakthrough innovation by accelerating innovation to nurture nascent projects from early innovation stage to full ability to scale.

Your role: 

• Work on a collaborative, interdisciplinary, and experienced medical robotics R&D team, tasked with inventing and launching the next generation of medical solutions for Philips’ Image Guided Therapies business.

• Architect and implement clinical-quality software solutions for a novel medical robot system in a medical-regulated environment with focus on requirements and feature definition, design, implementation, and use of robot software frameworks and multi-arm robot control algorithms; and integration in an Image Guided System.

• Participate in or lead software design discussions and code reviews (both internal and multi-functional) for robotic solutions and workflows; and follow quality & regulatory processes (ISO13485, IEC 62304).

• Join our Robotics team in our state-of-the-art R&D labs located at the Philips Innovation Campus in Cambridge, Massachusetts. 

You're the right fit if:  

• You’ve acquired 10+ years of professional experience developing software for medical devices and preferably for medical robots, as an individual contributor and a team lead with experience in robotic (HW/SW) control system design, integration, debugging, verification, and testing.

• Your skills include expert proficiency in C++, Python, Linux/Windows/RT Oses and experience with common frameworks and libraries (DDS, OpenCV, ROS, QT, WPF, QNX).  You have extensive experience in hands-on design and development and troubleshooting of embedded software and hardware-integrated systems; and relevant design patterns, data structures and architectures for distributed and multi-process RTOS applications.

• You have a MS, or PhD, in Computer Science, Computer Engineering, Electrical Engineering, or equivalent

• You are a self-motivated individual with good organizational and time management skills; and a strong desire to learn and adapt to new technologies and challenges.  You enjoy a high-paced professional environment but also can excel in individual contributions, as well as team collaboration using agile methodologies.

• You must be able to successfully perform the following minimum Physical, Cognitive and Environmental job requirements with or without accommodation for this position.  

Additional Information 

US work authorization is a precondition of employment. The company will not consider candidates who require sponsorship for a work-authorized visa, now or in the future. 

About Philips 

We are a health technology company. We built our entire company around the belief that every human matters, and we won't stop until everybody everywhere has access to the quality healthcare that we all deserve. Do the work of your life to help improve the lives of others.  

• Learn more about our business.  

• Discover our rich and exciting history.  

• Learn more about our purpose.  

• Read more about our employee benefits.  

If you’re interested in this role and have many, but not all, of the experiences needed, we encourage you to apply. You may still be the right candidate for this or other opportunities at Philips. Learn more about our commitment to diversity and inclusion here. 

#LI-PH1

#LI-Hybrid

Philips is an Equal Employment and Opportunity Employer/Disabled/Veteran and maintains a drug-free workplace.

Statistical Science Associate Director (Principal level) - Late Oncology

Location: Macclesfield, UK

Competitive salary and benefits

We are open to discussing working part-time (min 0.8FTE)

Do you have expertise in, and passion for, Biostatistics? Would you like to apply your skills to impact the early phases of drug development and regulatory interactions, in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious disease. But we're more than one of the world's leading pharmaceutical companies.

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us. With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing cutting-edge science with the latest technology to achieve breakthroughs. Backed by investment, we are aiming to deliver 6 new molecular entities by 2025.

We work on some of the most complex and interesting challenges. A fast-paced and agile team, we are empowered and trusted to innovate and experiment. With access to our extensive capabilities and comprehensive pipeline, you'll be involved in countless submissions and a wide range of engaging projects along the complete drug development process.

What you will do:

You will be expected to:

• Take a leadership role and drive statistical thinking in cross-functional team projects, within an international environment
• Contribute to strategic planning and quantitative decision making in early clinical development programmes
• Lead the delivery and oversight on drug project(s) and/or studies to time, quality and standards, including partnering with CROs and with Programming
• Participate in applying, adapting and/or developing statistical methodology
• Contribute to development of new procedures and standards to increase quality, efficiency, and effectiveness
  

Depending on your experience, the role may also include:

• Interactions to influence key stakeholders and governance
• Acting as a technical expert in interactions with external providers and collaborators
• Mentoring and coaching junior staff and supporting them with education and training in statistics
• Working with regulatory agencies, e.g. attending meetings, answering questions

We offer the chance to influence drug development and the opportunity to gain experience across a range of challenging and exciting projects.

Essential in the role:

• MSc/PhD in Statistics or Mathematics (containing a substantial statistical component) with experience in pharma/healthcare or other relevant area
• Knowledge of the technical and regulatory requirements related to the role
• Leadership capabilities to be able to lead and direct project work
• Experience of data analysis and interpretation in a relevant area
• Strong knowledge of programming in R and/or SAS
• Excellent written and spoken English. Excellent communication skills (including communicating with non-statisticians) and ability to build strong relationships
• Excellent collaboration skills required - the energy to work across global & functional boundaries, both internally and externally
• Ability to apply statistical expertise to complex problems, problem solving and quality focus

Desirable in the role, dependent on experience:

• Experience of programme and study design
• Experience in the relevant therapeutic area
• Experience of regulatory interactions

Why AstraZeneca?

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare.

So, what's next?

• Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.
• Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours.

Where can I find out more?

• Our Social Media, Follow AstraZeneca on LinkedIhttps://www.linkedin.com/company/1603/
• Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
• Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
• Our dedicated Biometrics page https://careers.astrazeneca.com/biometrics

Date role opened: 8th January 2024

Date role closed: 8th February 2024

A Vacancy at Cambridge University Hospitals NHS Foundation Trust.


We are looking for an experienced and enthusiastic communications and engagement manager to join the R&D Communications team.

You will be leading on communications and engagement projects related to the use of health data in research, with particular responsibility for delivery of communications aspects of the East of England Secure Data Environment project.

This role can either be office based (Barton House) or combined office/home based.

Produce content related to the EoE SDE and contribute to content on a variety of health-data and/or research related projects through R&D.

Identify and develop links with other health data research projects taking place on the Cambridge Biomedical Campus.

Support the development of internal and external communications, where required, by regular contact with partners, stakeholders and the R&D communications team.

Develop outputs including text, images, video and audio to reach target audiences and increase visibility with prospective followers.

Monitor new trends across the health data and translational research spaces, responding as appropriate to manage reputations.

Support the development and delivery of public engagement events, in collaboration with our partners.

Our Trust

Cambridge University Hospitals (CUH) NHS Foundation Trust comprises Addenbrooke’s Hospital and the Rosie Hospital in Cambridge. With over 11000 staff and over 1100 beds the priorities of the Trust focus on a quality service which is all about people – patients, staff and partners. Recognised as providing ‘outstanding’ care to our patients and rated ‘Good’ overall by the Care Quality Commissioner, is testament to the skill and dedication of the people who work here. CUH’s values – Together - Safe, Kind, Excellent – are at the heart of patient care, defining the way all staff work and behave. The Trust provides accessible high-quality healthcare for the local people of Cambridge, together with specialist services, dealing with rare or complex conditions for a regional, national and international population.

CUH is committed to promoting a diverse and inclusive community - a place where we can all be ourselves. We value our differences and fully advocate and support an inclusive working environment where every individual can fulfil their potential. We want to ensure our people are truly representative of all the communities that we serve. We welcome applications for all positions in the organisation irrespective of people’s age, disability, ethnicity, race, nationality, gender identity, sex, sexual orientation, religion or belief, marriage and civil partnership status, or pregnancy and maternity status or social economic background.

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities.

This vacancy will close at midnight on the 4th January 2024.

Interviews will be in the week commencing 12th January 2024.

Benefits to you

We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel.

Informal discussions about the post are welcome using the details below.

We welcome applications from the Armed Forces.


This advert closes on Thursday 4 Jan 2024

Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities. This vacancy will close at midnight on the 4th January 2024. Interviews will be in the week commencing 12th January 2024. Benefits to you We offer development opportunities and a wide range of benefits including on-site leisure facilities, shopping concourse, day nurseries and access to a great transport system with easy access to airports and rail travel. Informal discussions about the post are welcome using the details below. We welcome applications from the Armed Forces.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

On this page you will find a Role Profile which provides information about the hospital and full details about the role. We recommend that you review this and refer to it as you complete your application. Please include how you will meet the Trust Values Compassion, Excellence and Collaboration. If you would like more information about the role or working at Royal Papworth Hospital, please get in touch with the contact for this role.

Statistical Science Associate Director (Principal level) - Late Oncology

Location: Macclesfield, UK

Competitive salary and benefits

We are open to discussing working part-time (min 0.8FTE)

Do you have expertise in, and passion for, Biostatistics? Would you like to apply your skills to impact the early phases of drug development and regulatory interactions, in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world's most serious disease. But we're more than one of the world's leading pharmaceutical companies.

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It's our big vision that unites and inspires us. With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing cutting-edge science with the latest technology to achieve breakthroughs. Backed by investment, we are aiming to deliver 6 new molecular entities by 2025.

We work on some of the most complex and interesting challenges. A fast-paced and agile team, we are empowered and trusted to innovate and experiment. With access to our extensive capabilities and comprehensive pipeline, you'll be involved in countless submissions and a wide range of engaging projects along the complete drug development process.

What you will do:

You will be expected to:

• Take a leadership role and drive statistical thinking in cross-functional team projects, within an international environment
• Contribute to strategic planning and quantitative decision making in early clinical development programmes
• Lead the delivery and oversight on drug project(s) and/or studies to time, quality and standards, including partnering with CROs and with Programming
• Participate in applying, adapting and/or developing statistical methodology
• Contribute to development of new procedures and standards to increase quality, efficiency, and effectiveness
  

Depending on your experience, the role may also include:

• Interactions to influence key stakeholders and governance
• Acting as a technical expert in interactions with external providers and collaborators
• Mentoring and coaching junior staff and supporting them with education and training in statistics
• Working with regulatory agencies, e.g. attending meetings, answering questions

We offer the chance to influence drug development and the opportunity to gain experience across a range of challenging and exciting projects.

Essential in the role:

• MSc/PhD in Statistics or Mathematics (containing a substantial statistical component) with experience in pharma/healthcare or other relevant area
• Knowledge of the technical and regulatory requirements related to the role
• Leadership capabilities to be able to lead and direct project work
• Experience of data analysis and interpretation in a relevant area
• Strong knowledge of programming in R and/or SAS
• Excellent written and spoken English. Excellent communication skills (including communicating with non-statisticians) and ability to build strong relationships
• Excellent collaboration skills required - the energy to work across global & functional boundaries, both internally and externally
• Ability to apply statistical expertise to complex problems, problem solving and quality focus

Desirable in the role, dependent on experience:

• Experience of programme and study design
• Experience in the relevant therapeutic area
• Experience of regulatory interactions

Why AstraZeneca?

At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We're on an exciting journey to pioneer the future of healthcare.

So, what's next?

• Are you already imagining yourself joining our team? Good, because we can't wait to hear from you.
• Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours.

Where can I find out more?

• Our Social Media, Follow AstraZeneca on LinkedIhttps://www.linkedin.com/company/1603/
• Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
• Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
• Our dedicated Biometrics page https://careers.astrazeneca.com/biometrics

Date role opened: 11th December 2023

Date role closed: 8th January 2024