Total 20 science rd research job vacancies in Portsmouth, Hampshire, PO61SZ

A Research Technician position is available in the Centre for Cancer Immunology at Southampton General Hospital. This is a newly constructed, dedicated research building that is the result of a significant fund-raising campaign. It builds on a 40 year history of pioneering immunology and cancer research at Southampton, and represents the first dedicated cancer immunology centre in the UK. The activities in this centre span from pioneering discovery science to applied research and preclinical modelling and, crucially, onto first-in-human clinical trials and beyond. The centre houses world-class research facilities, including state-of-the-art scientific laboratories and a clinical trials unit.

The position is associated with the laboratory of Professors Ward and Ober. Their interdisciplinary research program is dedicated to the development of novel antibody-based therapeutics for the treatment of cancer and autoimmunity. This research has led to several therapeutics that are currently in advanced clinical trials or approved for clinical use. The group also develops advanced microscopy techniques for the evaluation of novel therapeutics in cellular environments. Their research is supported by major grants from the Welcome Trust, Cancer Research UK and support from collaborating biopharma companies.

The appointee will be highly motivated and excited by the challenges involved in supporting a dynamic, interdisciplinary group of researchers. The appointee’s role will be to provide support with the day-to-day running of the laboratory by providing technical support for the experimental work of post-doctoral fellows, research scientists and graduate students, combined with the ordering and maintenance of laboratory instrumentation and supplies. The position holder will be expected to be familiar with biosafety and other regulatory processes and follow these procedures as necessary.

It is essential to have a skill level equivalent to achievement of HNC, A-Level, NVQ3 with proven work experience acquired in relevant technical support roles and job-related training. The role requires the ability to plan and organise your workload, work well under pressure and communicate effectively and professionally with other laboratory members. A scientific knowledge in a biological field equivalent to B.Sc. level is extremely desirable.

The post-holders will possess relevant academic qualifications and work experience as well as good IT skills.

The position is for two years until 28/06/2026. Availability of funds for a period beyond the two-year timeframe is anticipated.

Informal enquiries should be directed to Professor Sally Ward (e.s.ward@soton.ac.uk).

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton! (University of Southampton | jobs.ac.uk)

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

The University is a signatory of the Technician Commitment and a partner affiliate of the National Technician Development Centre (NTDC). We are committed to supporting our technical staff and offer a wide range of opportunities including networking, mentoring, training, professional registration and career development. We really value all our technical staff and recognise the broad range of skills they have in support of education, research and enterprise activities. By joining you will be part of a bigger technical community, offering support and guidance.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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We are currently recruiting for Assistant Finance & Contracts Managers which is a pivotal role that helps to ensure the effective delivery of the finance and contracts service within our National Institute of Health and Care Research (NIHR) co-ordinating centre.

Who are we?

The NIHR funds, enables and delivers world-leading health and social care research that improves people's health and wellbeing and promotes economic growth. Our research helps turn discoveries into new or improved treatments, diagnostics, medical technologies and services. It provides those working in the NHS, public health, global health and social care with the evidence they need to better support patients, the public and people who need care.

Further information on the NIHR can be found at: www.nihr.ac.uk. In particular, you are encouraged to review our operational priorities and to watch this introductory video.

What will you be doing?

Working within the Finance and Contracts team you will be supporting the Finance Managers with the financial and contractual administration of research programmes. Some of the key tasks of the role are:

Reviewing and approving contracts and contract variation documentation
Reviewing projects financial reconciliation statements and proceeding tasks associated with financial assurance
Releasing, monitoring and reprofiling project payments
Providing support and advice on financial processes and procedures
Who are we looking for?

We are looking for candidates with a keen interest in the work we do and are highly numerate. We appreciate this is quite a unique finance role and we are able to offer training to ensure you are able to undertake all elements of the role. Some of the key skills we look for in a candidate are:

Comfortable with working with numbers
Ability to organise and prioritise your own workload
Be analytical and self-motivated
Able to work independently and problem solve as well as contributing to the wider team
Good communication skills both verbal and written
Proficient in the use of Microsoft office especially Excel
What can we offer you?

We recognise that our staff are at the heart of what we do so we make sure we look after you! As well as a generous benefits package (full details can be found here!), as an organisation we prioritise your wellbeing as reflected in the Mind Workplace Wellbeing awards, where we have achieved Gold for the fifth year in a row!

Our hybrid working approach helps you with your work life balance and offers you the chance to split your time between office and home working. We strive for cohesive and collaborative teams so our expectation is you spend around 20% of your time in the office. We also know that personal development is important and have a range of ways to support you with this.

For further information or an informal discussion, please contact Lindsay Mead: L.k.mead@soton.ac.uk

**Please note when in post the job title will be Assistant Research Awards Manager.

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We are seeking motivated postdoctoral scholars with a passion for flexible bioelectronics and medical robotics to join our dynamic research team. This project focuses on developing a smart bioelectronic system that seamlessly integrates therapeutic functions with continuous monitoring capabilities. The system incorporates cutting-edge technologies in bioelectronics, soft robotics, and materials science, leveraging advanced materials and fabrication technologies. If you are excited about groundbreaking research and innovative technology in healthcare engineering, this opportunity is perfect for you.

As a member of the Multiscale Intelligent Biodevices Lab (MIB), led by Dr. Rujie Sun at the University of Southampton, you will lead efforts to develop innovative bioelectronic systems that integrate real-time monitoring and therapeutic functions. Your primary focus will be designing and fabricating flexible bioelectronics that can interface seamlessly with biological tissues, combining soft robotic techniques to enhance personalized treatment. This role offers a unique opportunity to work on interdisciplinary projects, pushing the frontiers of personalized medicine and health management. In this project, you will collaborate with Inha University and have access to a broad network of academic partners, including Imperial College London, University of Oxford, University of Bristol, and University of Liverpool. Additionally, we work closely with industrial and clinical collaborators, providing opportunities for fostering new partnerships and expanding your professional network.

The successful applicant should have required qualifications and experience

Education: PhD in Biomedical Engineering, Electronic Engineering, Mechanical Engineering, Materials Science, or related disciplines with a strong academic record (Or working towards or nearing completion of a relevant PhD).
Research Interests: Demonstrated enthusiasm for research in flexible bioelectronics, soft medical robotics, or related fields.
Skills: Extensive experience in microfabrication techniques for bioelectronics or soft robotics, as well as expertise in biomaterials for medical tools. Strong collaboration skills, with the ability to work effectively in multidisciplinary teams, and excellent communication skills.
The University of Southampton is a global leader in research and innovation, among the top 1% of universities globally. Our electronic engineering programme was rated the best in the UK by the 2022 Guardian University Guide, and we were ranked 4th nationally for engineering in the 2021 Research Excellence Framework (REF). By joining us, you will be part of a supportive and vibrant academic community, with access to cutting-edge facilities and world-class research opportunities. This is an ideal environment for advancing your career while making significant contributions to the future of technology.

The post will be full time for 18 months with the possibility of further extension.

If you are interested, please submit your CV and a cover letter detailing how your skills and experience align with this role. For further inquiries, we encourage you to contact Dr. Rujie Sun at rujie.sun@soton.ac.uk.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

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You will work on the development of small uncrewed aircraft in the area of closely-coupled rotor research. This is part of the £1.2M Closely-Coupled Rotors EPSRC-funded research project in collaboration with colleagues in Aeronautics, Aeroacoustics and ISVR.

https://www.southampton.ac.uk/research/projects/aerodynamics-aeroacoustics-of-closely-coupled-rotors

The project will develop new methods and tools to design a new generation of urban unmanned aircraft. The project is specifically developed around a long-standing industrial challenge: reducing noise disruption caused by small multi-rotor uncrewed aircraft. The focus of the work at Southampton will consist of developing VTOL aerial platforms which can safely, reliably and quietly fly into urban cities to undertake servicing and delivery tasks. To enable this, new thinking is required in propulsion technology, particularly around the design of the propeller.

The project will contribute to:

Improved aerial operations in the urban environment.
Reduce noise disruption caused by urban servicing and delivery operations.
New thinking on flight within congested and cluttered environments.
Lobbying the regulation bodies, such as the CAA and EASA for relaxation of rules and permissions to operate in urban areas.
It is essential that you have a PhD or equivalent professional qualifications and experience in Unmanned Systems and have an excellent research track record. Further experience of designing, building and operating small multi-rotor aircraft would be advantageous.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

The University of Southampton is in the top one per cent of world universities and one of the UK’s top 15 research-intensive universities. We have an international reputation for research, teaching and enterprise activities. The successful candidate will join one of the UK’s most dynamic centres for engineering research and education, rated highly in the UK for research power in REF 2021.

Recent Publications from the group:

Analytical investigation of propeller-wing interaction noise
Deepak Akiwate, Anthony Parry, Phillip Joseph, & Chaitanya C. Paruchuri , 2022
DOI: 10.2514/6.2022-2877
Type: Conference

On the effect of inflow distortions of propeller noise
Federico Petricelli, Sergi Palleja Cabre, Chaitanya Paruchuri, Phillip Joseph, Amin Karimian, Stefano Meloni, & Roberto Camussi, 2022
DOI: 10.2514/6.2022-2938
Type: Conference

Investigation into the mechanisms of propeller-wing interaction noise
Chaitanya Paruchuri, Deepak Akiwate, Sergi Palleja Cabre, Amin Karimian, Phillip Joseph, & Anthony B. Parry, 2022
DOI: 10.2514/6.2022-2936
Type: Conference

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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We are seeking a full-time Research Fellow to support the NIHR ARC Wessex project FORTH – FORecasting Turbulence in Hospitals for a fixed term of 17 months. It is an exciting opportunity to be involved in interdisciplinary research that will underpin innovative solutions for healthcare management.

The Applied Research Collaboration (ARC) Wessex is an organisation funded by the National Institute of Health Research (NIHR) with a remit to support applied health and care research that responds to, and meets, the needs of local populations and local health and care systems. The NIHR ARC Wessex is one of 15 ARCs across England, which aims to improve the health and care of patients and the public within and beyond the Wessex region.

Our ARC conducts applied health research to improve patient outcomes; quality, delivery and efficiency of health and care services; increase the sustainability of health and care systems through collaborative partnership. We have a close relationship with regional stakeholders, including NHS organisations, universities, charities, local authorities and others.

FORTH aims to understand how demand surges for acute hospitals lead to slower and chaotic patient flow, a phenomenon we call turbulence, which affects the hospital's ability to deliver quality care. We will analyse a large dataset containing Electronic Health Records, aiming to define and understand the causes of turbulence. We will then create models for short-term prediction of turbulence, to help hospitals develop proactive demand management plans.

The successful candidate will to work with the team to achieve the objectives and be responsible for the technical work regarding data analysis and implementation of various models, which will require programming proficiency. For example, you will use artificial intelligence (machine learning) to predict the remainder of a patient's spell at a hospital, given their characteristics and the activities carried out in the current stay. You will also develop models that combine individual patient's predictions and future demand to predict short-term turbulence, with the goal of informing proactive demand management strategies. You will be part of an interdisciplinary team across the Business School, Health Sciences and Engineering who will work and collaborate closely with stakeholders from acute hospitals in the region.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

Education and skills required

- PhD in Operational Research, Mathematics, Statistics, Engineering or Computer Science (or equivalent).

- Detailed understanding and knowledge of programming languages, ideally C/C++ and Python or R.

- Solid background in machine learning predictive models, including theory and implementation.

- Working knowledge of stochastic modelling and Markov models.

- Experience with computational implementation of operational research or network optimisation models using appropriate software tools.

Salary and relevant information:

This is a full time post based at Southampton Business School, with salary compatible with a Level 4 Post-Doctoral Research position.

The employing organisation is the University of Southampton, which offers a competitive salary, pension scheme and other benefits.

For an informal discussion about the post, please contact Edilson Arruda, e.f.arruda@southampton.ac.uk.

As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. With a generous holiday allowance as well as additional university closure days we are committed to supporting our staff and students and open to a flexible working approach.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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The MarEA Project (Maritime Endangered Archaeology in the Middle East and North Africa) is a collaborative initiative led by the University of Southampton and Ulster University, in partnership with Oxford University. Our mission is to document and preserve the rich maritime archaeology of the coastal regions across the Middle East and North Africa (MENA).

We are seeking a motivated and skilled Researcher to join our team. In this role, you will contribute to the project’s success by conducting remote sensing research, collecting and analysing data across the MENA region, and supporting field surveys and training programs. This position will be based at the University of Southampton but will also require occasional travel to the MENA region.

Key responsibilities for the job are: 1) conduct research using remote sensing techniques and data collection methods across the MENA region, under the guidance of the project director; 2) Participate in ground surveys and contribute to training programs in selected countries within the project area; 3) Support the Principal Investigators (PIs) in achieving the project’s deliverables and advancing its objectives; 4) collaborate with an international team to ensure successful project outcomes.

Essential qualifications & skills we are looking for are: 1) extensive work experience in the MENA region; 2) proficiency in using GIS (Geographic Information Systems) for archaeological research; 3) strong organizational skills and the ability to manage multiple tasks effectively and 4) excellent communication skills, both written and verbal, to engage with diverse stakeholders.

The role will be primarily office-based at the University of Southampton, but flexibility is required, as overseas travel to the MENA region may be necessary.

This is an exciting opportunity for someone passionate about maritime archaeology and eager to make a meaningful impact in preserving the region’s cultural heritage.

If you are a proactive researcher with interest in the MENA region's archaeology and the required technical skills, we encourage you to apply.

Apply by uploading your CV and a cover letter detailing how your skills and experience match the requirements of the role.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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Research Fellow in Smart Fibre Optic High-Power Photonics (HiPPo): Development of the Digital Fibre Laser

About HiPPo

Standard multi-kW fibre lasers are now routinely used in the most advanced production lines for cutting, welding, 3D printing, and marking of a myriad of materials from glass to steel. The ability to precisely control the properties of the laser beam and focus it on the workpiece makes high-power fibre lasers (HPFLs) indispensable to modern manufacturing. As we enter the Digital Manufacturing/Industry 4.0 era however, new challenges and opportunities for HPFLs are emerging.

The primary objective of the HiPPo project (Smart Fibre Optic High-Power Photonics, www.hippo-laser.co.uk) is to move beyond the “fixed” fibre lasers that are currently used in manufacturing, and towards “smart” fibre lasers that are automatically reconfigured and optimised in real-time depending on the application. This ambitious objective requires research breakthroughs across the spectrum of fibre laser development, from the development of new fibre core materials, to addressing limits imposed by SBS and TMI, to high-speed beam and polarisation shaping, to multi-channel kW level energy delivery, and finally using deep learning to solve the complexity challenge associated with coherent beam combination.

The role

Within HiPPo, your specific task will be to develop a ‘digital fibre laser’, through the neural-network control of a tiled array of fibre lasers in a coherent beam combination architecture, for unlocking novel power scaling and beam shaping capabilities in real-time. You will work at the Optoelectronics Research Centre (www.southampton.ac.uk/about/faculties-schools-departments/optoelectronics-research-centre) in a project team of eight PDRAs focused on delivering the next generation of HPFLs. You will have access to our state-of-the-art cleanroom facilities (www.zeplerinstitute.com/facilities), and be led by a team of world leading experts in the fibre laser and deep learning domains.

About you

You will have a PhD or equivalent professional qualifications and experience in an experimental discipline, ideally with experience in fibre optics and low-noise lasers and optical amplifiers, along with their practical implementation. Applications are also welcome from candidates nearing completion of a relevant PhD qualification. Whilst this is a laser development project, awareness of deep learning techniques is beneficial as you will be working closely with deep learning specialists.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

What we offer

The University of Southampton is in the top 1% of world universities and in the top 10 of the UK’s research-intensive universities. We are committed to sustainability and being a globally responsible university. We have recently been awarded the Platinum EcoAward, and strive to embed sustainability into all aspects of our individual and collective work. We aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. With a generous holiday allowance, we are committed to supporting our staff and are open to flexible working.

To informally discuss the position, contact Prof Johan Nilsson (jn@orc.soton.ac.uk) or Dr Ben Mills (bm602@orc.soton.ac.uk). Please quote the advert reference on all correspondence.

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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Section
Civil, Maritime & Environmental Engineering
Location:
Southampton Science Park, Chilworth
Salary
£34,980 to £42,978
Full Time Fixed Term (until 30/04/2025)
Closing Date:
Monday 16 September 2024
Reference
2850624DA
Research Technician
A research technician with expertise in fermentation and biofilm is sought to work on the development of biofilm for acid fermentation using waste hydrolysate. The post is funded as part of a PoC project on biomass waste to chemicals with CO2 fixation, aiming for negative carbon emissions in biorefinery. The main focus will be utilising the natural flocculation capability of a specific pure strain to form biofilm for platform acid fermentation, enabling sugar-rich hydrolysate-based fermentation possible for acid production and carbon fixation. The project will involve biofilm assays, fermentation, and inventory establishment for preliminary life cycle assessment. Developing bio-based platform chemicals from waste to replace or complement petroleum-derived chemicals is critical to moving towards a circular economy. The utilisation of CO2 as a co-substrate in this project will further support the transition to net zero.

Essential requirements

PhD in Bioengineering, (Bio)chemical Engineering, Biotechnology or a closely related discipline, or equivalent research, industrial or commercial experience

Expertise and experience in fermentation using monoculture (using anaerobic or facultative monoculture preferred)

Capability of working under your own initiative while collaborating with the project members

The following knowledge, skills & experience is desirable:

Detailed understanding and knowledge of industrial fermentation

Detailed understanding and knowledge of biomass hydrolysis

Practical experience with fermentation in bioreactors

Further Information

The post is a fixed-term contract for 6.5 months from 14 October 2024 to 30 April 2025.

Full details of the role and the skills, knowledge and experience required can be found in the Job Description document, via the above ‘Apply’ button.

Should you require any further details on the role please contact: Dr Yongqiang Liu – Y.Liu@soton.ac.uk

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This multi-disciplinary project offers an exciting opportunity for a postdoctoral researcher with a strong interest in exploring the interactions of microbial cells with each other and their environment.

The post holder will develop innovative approaches to define the mechanisms of chemical and physical interactions between cells that result in changes in gene expression, metabolism, cell morphology or even inhibition of competing populations. Findings will be both fundamentally important and provide insights into e.g., the filamentous/invasive growth of pathogenic yeast, novel microbial strategies to suppress spoilage organisms in foods and beverages, or opportunities to disrupt the impact of vector insects such as the pest Drosophila suzukii fruit fly.

The post holder will join the lab of Prof Vladimir Jiranek that recently relocated to the University of Southampton (Prof V Jiranek | Uni Soton), and have the opportunity to interact with several PhD students working on related topics in the context of a diverse and successful School of Biological Sciences (https://www.southampton.ac.uk/about/faculties-schools-departments/school-of-biological-sciences). The Jiranek lab also works extensively with international yeast biotechnology companies, thereby offering a vital industrial perspective on the work and the potential for future joint funding or employment opportunities.

Based in the Life Sciences Building at the University’s Highfield Campus, the post is ERE level 4, full time and available for 2 years in the first instance. The term may be extended subject to the success of funding applications.

Southampton, and nearby Winchester, are great cities to live in and are <1.5 hr train journey from London and near international airports linking you to the world.

Applicants should have a PhD or equivalent professional qualification and experience in microbiology, biotechnology or a related field.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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We have an exciting opportunity for a Principal Research Fellow to work across all the research themes comprising ARC Wessex. You will work closely with the ARC research theme and project leads, taking responsibility for advice and consultancy on statistical matters relating to project design, and will also be responsible for statistical analysis or statistical mentoring for quantitative researchers, as required by a given project.

Candidates are expected to have a PhD which contains a significant use of applied statistical methods.

In addition, candidates should possess strong programming skills in at least two major statistical software languages, with a willingness and flexibility to learn to program in other statistical software packages, as required. You should have good communication skills, possess initiative, and be able to work effectively within teams of different sizes, disciplines and which potentially comprise team members from a range of organisations (e.g. academic, NHS, funding bodies). The ability to engage with clients in a statistical consulting scenario is essential.

The Applied Research Collaboration (ARC) Wessex is an organisation funded by the National Institute of Health Research (NIHR) with a remit to support applied health and care research that responds to, and meets, the needs of local populations and local health and care systems. The NIHR ARC Wessex is one of 15 ARCs across England, part of a £135 million investment by the NIHR to improve the health and care of patients and the public within and beyond the Wessex region.

Our ARC conducts applied health research with the aims to improve outcomes for patients and public; improve quality, delivery and efficiency of health and care services; increase the sustainability of health and care systems locally and nationally, through collaborative partnership. We have a close relationship with our stakeholders within the region, which include a wide range of NHS organisations, local universities, charities, local authorities and others.

The successful applicant should be willing to travel within the Wessex area, as required, and occasionally further afield within the UK.

The employing organisation is the University of Southampton which offers a competitive salary, pension scheme and other benefits.

For informal discussions please contact Richard Trowbridge (R.M.Trowbridge@soton.ac.uk).

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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The School of Geography and Environmental Science seeks to appoint a Research Fellow to work on a UKRI-funded project led by Dr Zoë Thomas, entitled “The View from the South: New approaches for understanding mechanisms and impacts of climate tipping points”. This project will pioneer the development of new proxies of wind strength and temperature records from the South Atlantic, using the latest technologies and interdisciplinary techniques.

The project aims to identify the relationships between southern hemisphere atmospheric circulation shifts and global climate tipping points. The Research Fellow will work on several tasks: (1) undertake laboratory work to generate new palaeoclimate records from South Atlantic peat sediments, (2) assemble and chronologically align datasets from the Atlantic Basin, and (3) undertake statistical and time series analysis to explore the latitudinal propagation of climate signals.

The post holder will have the opportunity, subject to starting date and travel restrictions, to undertake fieldwork in the South Atlantic during the post tenure.

The post is tenable from 1st October 2024 and is fixed term for 3.5 years.

The post will be based at the University of Southampton. You will be working with Dr Zoë Thomas in the School of Geography and Environmental Science, Dr Gordon Inglis in the School of Ocean and Earth Science, and a team of PhD students, postdocs and other collaborators based in the UK and overseas. The team is friendly, collaborative, and inclusive and any candidate will be welcomed as an equal member of the community.

Job criteria:

PhD or equivalent professional qualification and experience in palaeoclimate reconstruction from sediment archives.
Detailed understanding and knowledge of the reconstruction of palaeoclimate from Quaternary sedimentary deposits using biomarkers and other multiple proxies.
Knowledge and experience of palaeoclimate laboratory methods for reconstructing climate from sediment cores using organic geochemistry.
Evidence of experience and aptitude in statistical methods for time series analysis and data syntheses methods.
Excellent written and oral communication skills and time management skills
The University of Southampton is in the top 1% of world Universities and one of the UK’s top 10 research-intensive universities. We have an international reputation for research, teaching and enterprise activities. The School of Geography and Environmental Science at the University of Southampton is committed to creating an environment where everyone can thrive, and we aim to be proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. We are a signatory to the Concordat to Support the Career Development of Researchers and can provide opportunities for career development and mentoring.

Equality, Diversity and Inclusion | University of Southampton

Working at the University of Southampton:

Check out the staff benefits and why you should join us at The University of Southampton!

For further enquiries please contact Dr Zoë Thomas (z.thomas@soton.ac.uk).

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

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Autistic adolescents have 3 - 6 times higher risks compared to typical adolescents to develop Mental Health Disorders (MHD). The aim of the European Commission and UKRI funded ETHEREAL project is to develop an AI tool that will help them to reduce that risk.

Recent research established a central role played by epigenetic-genetic-metabolomic interaction processes in determining mental health throughout the life particularly in genetically predisposed individuals. These findings lead to the following hypothesis and aims of ETHEREAL:

Hypothesis: Quantitative modelling of the Epigenetic – Genetic/metabolomic – Mental health (EGM) cascades will identify 1) the precise environmental factors causally responsible for transition of mental state of an autistic adolescent to MHD, and 2) their possible control mechanisms, and thereby 3) will provide a set of formal neurobiologically informed selection criteria of the most appropriate adolescent-centric evidence based intervention in autistic adolescents.

Vision: Designing an ecosystem to prevent MHD in adolescents with ASD by 1) empowering them to self-control their personal environmental risk factors whilst, 2) accessing proper evidence based interventions seamlessly in their “Personal Natural Environment” (PNE) improving their Quality of Life and independent living.

Aim: Quantitative characterisation of the EGM cascades and its integration into a personalised, flexible, single service delivery model for seamless access to care service in the PNE of an autistic adolescent empowering them to take preventive actions against MHDs. This will be done through the following four activities:

1: Identification of the environmental factors in the PNE of an autistic adolescent which instigate transition of their “mental health” to MHD (Model 1).

2: Quantitative modelling of the EGM process chain in autistic adolescents for designing control strategies based on their PNE, historical and current states (Model 2).

3: Integration of the Models 1 and 2 in the form of a Personalized Digital Nurse (PDN) mobile app, that will empower autistic adolescents to self-control the epigenetic influence of the factors present in their PNE.

4: Integration of the PDN with their PNE and the community care services and evaluation of the complete system informing the design of a personalized service delivery model (Model 3) based on Implementation Science principles for rapid uptake.

We are seeking highly motivated individuals who already have a PhD degree or are about to submit/have submitted their doctoral thesis to join ETHEREAL project to work on the Model 1 and 2. You should have worked in the area of dynamic system modelling with knowledge of signal processing and machine learning as all three areas are essential to achieve the aims. You should have a proven track record in at least one of these areas and are motivated to learn the other areas as per the requirement of the project. You will work in a team of electronics and computer scientists, clinicians, biologists and software developers. Very good interpersonal communication skill is essential.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

We are committed to equality, diversity and inclusion and welcome applicants who support our mission of inclusivity.

Apply by 11.59 pm GMT on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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We are looking for a motivated Post-Doctoral Research Fellow to work with Amrit Mudher and Phil Williamson developing methods to investigate how the cellular milieu influences the folding, structure and function of large molecular complexes including amyloid fibre structure and integral membrane proteins. This Leverhulme Trust funded project will combine the powerful genetic tractability of Drosophila melanogaster with the molecular resolving power of modern sensitive solid-state NMR experiments to report on the structure, dynamics, and function of these assemblies in-vivo.

The project will build on preliminary studies that have demonstrated that modern proton detected ultra-high field solid-state NMR methods can provide the necessary resolution and sensitivity to study the structure and dynamics of large molecular complexes in-situ in the model organism Drosophila melanogaster. The project seeks to establish workflow that will enable the induced expression and labelling of macromolecular complexes and a range of NMR methodologies that permit the characterization of their structure and dynamics as well as interactions with other cellular components.

Ideally applicants should possess a PhD in biochemistry (or related descipline) and ideally experience in either Drosophila research and/or solid-state NMR. The position will be based in the School of Biolgical Sciences, which provides state of the art facilities for invertebrate research and solid-state NMR research (both locally and through the UK National Research Facility). To discuss the position, please don’t hesitate to contact Prof Amrit Mudher (A.Mudher@soton.ac.uk) or Prof Phil Williamson (P.T.Williamson@soton.ac.uk).

*Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

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As a university we aim to create an environment where everyone can thrive and are proactive in fostering a culture of inclusion, respect and equality of opportunity. We believe that we can only truly meet our objectives if we are reflective of society, so we are passionate about creating a working environment in which you are free to bring your whole self to work. With a generous holiday allowance as well as additional university closure days we are committed to supporting our staff and students and open to a flexible working approach.

This role does not qualify for Skilled Worker Visa sponsorship. To explore alternative UK visas, see gov.uk.

Apply by midnight on the closing date. For assistance contact Recruitment on +44(0)2380 592750 or recruitment@soton.ac.uk quoting the job number.

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Location: Southampton General Hospital
Salary: £34,980 to £39,347 per annum
Full Time Fixed Term for 18 months
Closing Date: Thursday 18 April 2024
Interview Date: To be confirmed
Reference: 2665024CM
Postdoctoral Fellow in Cancer Immunology

Antibody and Vaccine Group, Centre for Cancer Immunology, University of Southampton, Faculty of Medicine, School of Cancer Sciences

Monoclonal antibodies (mAb) are now established as effective treatments for cancer, albeit with considerable potential for further improvement. The Antibody and Vaccine Group based in the Centre for Cancer Immunology in Southampton has a strong track-record in basic and translational immunology relating to developing therapeutic mAb for clinical examination.

We are currently running an extensive programme of research led by Profs Mark Cragg, Stephen Beers, Bjorn Frendeus and Sean Lim to develop new and more effective antibody reagents for cancer patients. The current opportunity is for a research fellow to join the team to help dissect mechanisms of action for mAb capable of manipulating immune and tumour cells to elicit powerful anti-tumour responses, with the potential for a direct impact on clinical development.

You will be motivated, educated in a relevant subject area and have practical laboratory experience of antibody biology and in vivo methodology.

Informal queries should be directed to Professor Mark Cragg (msc@soton.ac.uk)

Details about the Antibody and Vaccine Group, Cancer Sciences and Centre for Cancer Immunology can be found at https://www.southampton.ac.uk/research/institutes-centres/antibody-vaccine-group; https://www.southampton.ac.uk/research/groups/cancer-sciences; https://www.southampton.ac.uk/research/institutes-centres/centre-for-cancer-immunology

Applications will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification. The title of Research Fellow will be applied upon completion of PhD. Prior to the qualification being awarded the title of Senior Research Assistant will be given.

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The Retinal Cell Biology Lab at the University of Southampton seeks to recruit a capable and highly motivated postdoctoral researcher for a 3 year project at the intersection of basic and translational research. The successful candidate will join the multidisciplinary Faculty of Medicine’s Vision Group, composed of both basic scientists and clinicians, providing a rich environment for exciting professional and personal development.

Taking advantage of human ESC derived retinal organoid cultures the post holder will work on a collaborative project seeking to understand photoreceptor physiology.

Candidates should have a PhD (or about to be awarded) in a relevant life sciences area and a BSc/MSc in a related subject (e.g. developmental cell biology/genetics). Knowledge of mammalian cellular and developmental biology is essential. The candidate will have robust skills in molecular biology techniques as well as robust experience in pluripotent stem cell culture, organoid differentiation, histology, flow cytometry and confocal microscopy. Experience with using the programming language R is desirable. The candidate must have excellent organisational, communication and problem solving skills.

A successful track-record in research, as evidenced by having published at least one primary research article in the past five years in a peer-reviewed journal, is required.

Applications for Research Fellow positions will be considered from candidates who are working towards or nearing completion of a relevant PhD qualification if the above requirements are met. The title of Research Fellow will be applied upon successful completion of the PhD. Prior to the qualification being awarded the title Senior Research Assistant will be given.

Previously unsuccessful applicants need not apply.

For further information please contact: Dr Jörn Lakowski (j.lakowski@soton.ac.uk)

Application Procedure

The application deadline is midnight on the closing date stated above. If you need assistance, call Recruitment on +44 (0) 23 8059 2750, or email recruitment@soton.ac.uk. Quote the advert reference 2606624FC-R on all correspondence.

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